Naphthalen

General

Naphthalene is an organic compound with formula C10H8 a fused pair of benzene rings. It is best known as the main ingredient of traditional mothballs. It is the simplest polycyclic aromatic hydrocarbon. Building block for many inhibitors of enzymes

Inhibitor	Main targeted enzyme families	Type
Amylovis-201		Sulfur Compound Naphthalen
Benzothiazole-phenyl-thioacetamide-Cpd30	ACHE	Monoamine-oxidase-inhibitor Multitarget Naphthalen Benzothiazol Sulfur Compound
Duloxetine	BCHE	Drug Multitarget Sodium:neurotransmitter symporter Naphthalen Sulfur Compound Thiophen
MGLL-IN-Cpd34	Monoglyceridelipase_lysophospholip	Piperazine Naphthalen Naphthylamide
CHEMBL4559005	Monoglyceridelipase_lysophospholip	Naphthalen Piperazine Pyrazole Cyanide
Naphthalen-1-yloxymethyl-triazol-thiazol-cpd35a	BCHE	Naphthalen Triazol Thiazole Sulfur Compound
Naphthalen-2-yloxymethyl-triazol-thiazol-cpd37a	BCHE	Naphthalen Triazol Thiazole Sulfur Compound
Hydrazide-Hydrazone-Cpd12	ACHE BCHE	Carbonic anhydrase inhibitor Multitarget Derivative of Nicotine Benzoate Naphthalen
1-Naphtol	Duf_1100-S	Naphthalen
1,3-Dihydroxynaphthalene	Duf_1100-S	Naphthalen
1,3,6,8-Tetrahydroxynaphthalene	Duf_1100-S	Naphthalen
ADS031	ACHE	Histamine-Receptor3-H3-Antagonist Multitarget Piperidine Naphthalen
Amiridine-Admantyl-5d	BCHE	Quinoline Derivative of Tacrine Derivative of Amiridine Adamantyl NMDA-Ligand Multitarget Naphthalen
(R)-BEL		Not AlphaBeta Hydrolase target Naphthalen
C4I-7QHE	BCHE	Acridine Alkyl linked bis-ligand Derivative of Tacrine Carboxamide Derivative of Donepezil Naphthalen Piperidine
Aromatic-tertiary-amine-17c	BCHE	Naphthalen Carboxamide
XM-47	RsbQ-like	Naphthalen Strigolactone receptors ligand
2-methoxy-1-naphthaldehyde	RsbQ-like	Naphthalen Strigolactone receptors ligand
Fragment-714	Pectinacetylesterase-Notum	Fragment inhibitor of Notum Morpholine Naphthalen
1-Naphthalenepentanoic-acid	Pectinacetylesterase-Notum	Fragment inhibitor of Notum Naphthalen
2-(1,2-Dihydroacenaphthylen-5-ylsulfanyl)acetic-acid	Pectinacetylesterase-Notum	Fragment inhibitor of Notum Naphthalen Sulfur Compound
ZINC395065-W9L-4C4Z	Epoxide_hydrolase	Urea derivative Naphthalen
4-Oxo-beta-Lactam-A272	DPP4N_Peptidase_S9	Piperazine beta-Lactam Naphthalen
4-Oxo-beta-Lactam-A272-closed	DPP4N_Peptidase_S9	Piperazine beta-Lactam Naphthalen
6RUA-3a	BCHE	Sulfur Compound Sulfonamide Coumarin Piperidine Carboxamide Naphthalen Chromen
JU5	BCHE	Coumarin Piperidine Carboxamide Naphthalen Sulfur Compound Chromen
JUB	BCHE	Piperidine Piperazine NBD-nitro-benzoxadiazol-fluorescent Benzoxadiazole Sulfur Compound Sulfonamide Naphthalen
CHEMBL4069230	PAF-Acetylhydrolase	Sulfur Compound Naphthalen
CHEMBL4075815	PAF-Acetylhydrolase	Sulfur Compound Cyanide Naphthalen
5LKR-6yc	BCHE	Piperidine Carboxamide Naphthalen Alkyne
5DYT-5hb	BCHE	Piperidine Derivative of Donepezil Sulfonamide Sulfur Compound Naphthalen
5DYY-5hh	BCHE	Piperidine Derivative of Donepezil Sulfonamide Sulfur Compound Naphthalen
dansyl-PEG2-HaloTag	Haloalkane_dehalogenase-HLD2	Polymer Poly-ethylene-glycol Sulfonamide Sulfur Compound HaloTag-ligand Naphthalen
(R)-3-[1]naphthyloxy-propane-1,2-diol	Epoxide_hydrolase	Naphthalen
Naphthalen-2-ylboronic-acid	Carb_B_Arthropoda	Naphthalen Boron compound
5DYW-5hf-C11	BCHE	Piperidine Derivative of Donepezil Sulfur Compound Sulfonamide PET probe Naphthalen
5DYW-5hf	BCHE	Piperidine Derivative of Donepezil Sulfur Compound Sulfonamide Naphthalen
Ala(1-naph)-Pro-CN	Hydrolase_RBBP9_YdeN DPP4N_Peptidase_S9	Peptide Pyrrolidine Naphthalen Cyanide
JW480	Arylacetamide_deacetylase	Carbamate Naphthalen
3F9	BCHE	Piperidine Inden Carboxamide Naphthalen
Chlorotacrine-juglone	ACHE	Multitarget Antioxidant Derivative of Tacrine Acridine Alkyl linked bis-ligand anti-Abeta-aggregation Naphthalen
SB-1436	BCHE ACHE	Pyridine Naphthalen Pyridinium anti-Abeta-aggregation
Mevastatin	Carboxylesterase Carb_B_Chordata	Drug Natural Not AlphaBeta Hydrolase target Naphthalen Antibiotic