BDBM50138750
IC50 20 nM
General
Type : Triazol, Sulfur Compound, Carboxamide
Chemical_Nomenclature : 3-(4-chlorophenyl)-N,N-dimethyl-5-methylsulfanyl-1,2,4-triazole-1-carboxamide
Canonical SMILES : CN(C)C(=O)N1C(=NC(=N1)C2=CC=C(C=C2)Cl)SC
InChI : InChI=1S\/C12H13ClN4OS\/c1-16(2)12(18)17-11(19-3)14-10(15-17)8-4-6-9(13)7-5-8\/h4-7H,1-3H3
InChIKey : BCRUIWHBJPICOM-UHFFFAOYSA-N
Other name(s) : CHEMBL130098 || Maybridge4_004377 || SCHEMBL5646461 || HMS1533G21 || BDBM50138750
MW : 296.78
Formula : C12H13ClN4OS
CAS_number :
PubChem : 2743222
UniChem : BCRUIWHBJPICOM-UHFFFAOYSA-N
Target
Families : BDBM50138750 ligand of proteins in family
Hormone-sensitive_lipase_like
Protein :
human-LIPE
References (1)
| Title : Synthesis and structure-activity relationship for a novel class of potent and selective carbamoyl-triazole based inhibitors of hormone sensitive lipase - Ebdrup_2004_J.Med.Chem_47_400 |
| Author(s) : Ebdrup S , Sorensen LG , Olsen OH , Jacobsen P |
| Ref : Journal of Medicinal Chemistry , 47 :400 , 2004 |
| Abstract : |
| PubMedSearch : Ebdrup_2004_J.Med.Chem_47_400 |
| PubMedID: 14711311 |
| Gene_locus related to this paper: human-LIPE |