Banol

. Carbanolate : L. cuprina AChE, IC50 [nM] 162 +/- 13 ; Human AChE, IC50 [nM] 977 +/- 109

General

Type : Carbamate, Organochlorine

Chemical_Nomenclature : (2-chloro-4,5-dimethylphenyl) N-methylcarbamate

Canonical SMILES : CC1=CC(=C(C=C1C)Cl)OC(=O)NC

InChI : InChI=1S\/C10H12ClNO2\/c1-6-4-8(11)9(5-7(6)2)14-10(13)12-3\/h4-5H,1-3H3,(H,12,13)

InChIKey : QRTXZGIQTYDABO-UHFFFAOYSA-N

Other name(s) : Carbonalate  ||  Carbanolate  ||  Chloroxylam  ||  Caswell No. 219  ||  Upjohn U-12,927  ||  Banol Tuco Sok  ||  OMS-174  ||  SCHEMBL119665  ||  SCHEMBL29765595


MW : 213.66

Formula : C10H12ClNO2

CAS_number : 671-04-5

PubChem : 12636,    522251

UniChem : QRTXZGIQTYDABO-UHFFFAOYSA-N

Target

Families : Banol ligand of proteins in family
ACHE

References (2)

Title : The characterization of Lucilia cuprina acetylcholinesterase as a drug target, and the identification of novel inhibitors by high throughput screening - Ilg_2011_Insect.Biochem.Mol.Biol_41_470
Author(s) : Ilg T , Cramer J , Lutz J , Noack S , Schmitt H , Williams H , Newton T
Ref : Insect Biochemistry & Molecular Biology , 41 :470 , 2011
Abstract :
PubMedSearch : Ilg_2011_Insect.Biochem.Mol.Biol_41_470
PubMedID: 21530657

Title : The detection of cholinesterase inhibition in erythrocytes of rats fed low levels of the carbamate Banol -
Author(s) : Casterline JL, Jr. , Williams CH
Ref : Journal of Laboratory & Clinical Medicine , 69 :325 , 1967
PubMedID: 6016627