Benzothiazol-chlorophenyl-thiadiazol-thio-acetamide-cpd10b
IC50 AChE 0.050 +/- 0.02 microM
General
Type : Benzothiazol, Thiadiazol, Sulfur Compound
Chemical_Nomenclature : N-(1,3-benzothiazol-2-yl)-[(4-chlorophenyl)-1,3,4-thiadiazol-2-ylthio]ethanamide
Canonical SMILES : C1=CC=CC2=C1N=C(S2)NC(CSC3=NN=C(S3)C4=CC=C(C=C4)Cl)=O
InChI : InChI=1S\/C17H11ClN4OS3\/c18-11-7-5-10(6-8-11)15-21-22-17(26-15)24-9-14(23)20-16-19-12-3-1-2-4-13(12)25-16\/h1-8H,9H2,(H,19,20,23)\
InChIKey : WEOGQXCOCOQFPN-UHFFFAOYSA-N
Other name(s) : Compound 10b || N-(1,3-Benzothiazol-2-yl)[5-(p-chlorophenyl)-1,3,4-thiadiazol-2-ylthio]acetamide
Target
Families : Benzothiazol-chlorophenyl-thiadiazol-thio-acetamide-cpd10b ligand of proteins in family
ACHE
Protein :
human-ACHE
References (1)
| Title : Computational drug design, synthesis, acetylcholinesterase inhibition and kinetic evaluation of novel benzothiazole-thiadiazole\/oxadiazole derivatives - Ambatwar_2026_Future.Med.Chem__1 |
| Author(s) : Ambatwar R , Singh P , Ghosh S , Chandrakar L , Datusalia AK , Khatik GL |
| Ref : Future Med Chem , :1 , 2026 |
| Abstract : |
| PubMedSearch : Ambatwar_2026_Future.Med.Chem__1 |
| PubMedID: 42836360 |