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Thiadiazol

General

Five-membered heterocyclic compounds containing one sulfur and two nitrogen atoms. Building block for many inhibitors of enzymes
Inhibitor Main targeted enzyme families Type Structure
Imidazo-thiadiazole-cpd20aa ACHE Triazol Thiadiazol Sulfur Compound Trifluoro Imidazole
Triazolo-thiadiazole-Cpd4k BCHE ACHE Triazol Thiadiazol Sulfur Compound
AKOS002054853 ACHE Triazol Thiadiazol Sulfur Compound
CHEMBL3338952 BCHE Triazol Thiadiazol Pyridine Sulfur Compound
MTDZ ACHE Sulfur Compound Thiadiazol Sulfonyl
JZP-430 ABHD6-Lip Carbamate Morpholine Sulfur Compound Thiadiazol
JZP-MA-11 ABHD6-Lip Sulfur Compound PET probe Thiadiazol Piperidine Carbamate
Lalistat-alkyne-probe Acidic_Lipase 6_AlphaBeta_hydrolase Cutinase Hormone-sensitive_lipase_like Monoglyceridelipase_lysophospholip Piperidine Lipase inhibitor Sulfur Compound Thiadiazol Alkyne ABPP-Probe
N-dodecyl-pyridinyl-1,3,4-thiadiazol-amine-3t ACHE Sulfur Compound Pyridine Thiadiazol
Fragment-955 Pectinacetylesterase-Notum Fragment inhibitor of Notum Sulfur Compound Thiadiazol
Fragment-276 Pectinacetylesterase-Notum Fragment inhibitor of Notum Sulfur Compound Thiadiazol
TDZD8 Pectinacetylesterase-Notum Not AlphaBeta Hydrolase target GSK-3 kinase inhibitor Thiadiazol Sulfur Compound
Lalistat-1 Acidic_Lipase Hormone-sensitive_lipase_like Monoglyceridelipase_lysophospholip Cutinase 6_AlphaBeta_hydrolase Piperidine Lipase inhibitor Sulfur Compound Thiadiazol
Lalistat-2 Acidic_Lipase Hormone-sensitive_lipase_like Monoglyceridelipase_lysophospholip Cutinase 6_AlphaBeta_hydrolase Piperidine Lipase inhibitor Sulfur Compound Thiadiazol Carbamate
P9-benzothiadiazole Haloalkane_dehalogenase-HLD2 Sulfur Compound Fluorescent Probe Thiadiazol Sulfonyl
Methidathion ACHE Organophosphate Insecticide Sulfur Compound Organothiophosphate Thiadiazol