Bis-nitro-oxoindolin-ylidenehydrazine-carbothiohydrazide-cpd1
thiosemicarbazone-based isatin: IC50 AChE 0.20 +/- 0.05 microM
General
Type : Indole, Urea derivative, Sulfur Compound, Isatin
Chemical_Nomenclature : N',2-bis((Z)5-nitro-2-oxoindolin-3-ylidene)hydrazine-1-carbothiohydrazide
Canonical SMILES : N4C1=CC=C([N+](=O)[O-])C=C1C(=N\/NC(NN=C3C2=CC(=CC=C2NC3=O)[N+](=O)[O-])=S)C4=O\
InChI : InChI=1S\/C17H10N8O6S\/c26-15-13(9-5-7(24(28)29)1-3-11(9)18-15)20-22-17(32)23-21-14-10-6-8(25(30)31)2-4-12(10)19-16(14)27\/h1-6H,(H,18,20,26)(H,19,21,27)(H2,22,23,32)
InChIKey : LYZASPARDUBKQC-UHFFFAOYSA-N
Other name(s) :
Target
References (1)
| Title : Synthesis, in vitro bio-evaluation, and molecular docking study of thiosemicarbazone-based isatin\/bis-Schiff base hybrid analogues as effective cholinesterase inhibitors - Khan_2023_J.Mol.Struct_1284_135351 |
| Author(s) : Khan S , Ullah H , Hussain R , Khan Y , Khan MU , Khan M , Sattar A , Khan MS |
| Ref : Journal of Molecular Structure , 1284 :135351 , 2023 |
| Abstract : |
| PubMedSearch : Khan_2023_J.Mol.Struct_1284_135351 |
| PubMedID: |