Bromhexine
Bromhexine is mucolytic agent used for a variety of respiratory conditions associated with increased mucus secretion. It is derived from the Adhatoda vasica plant and aids in the clearance of excess mucus, improving breathing and reducing cough
General
Chemical_Nomenclature : 2,4-dibromo-6-[[cyclohexyl(methyl)amino]methyl]aniline
Canonical SMILES : CN(CC1=C(C(=CC(=C1)Br)Br)N)C2CCCCC2
InChI : InChI=1S\/C14H20Br2N2\/c1-18(12-5-3-2-4-6-12)9-10-7-11(15)8-13(16)14(10)17\/h7-8,12H,2-6,9,17H2,1H3
InChIKey : OJGDCBLYJGHCIH-UHFFFAOYSA-N
Other name(s) : Benzenemethanamine, 2-amino-3,5-dibromo-N-cyclohexyl-N-methyl- || Bromhexina || Bromhexinum || Fluibron
MW : 376.13
Formula : C14H20Br2N2
CAS_number : 3572-43-8
PubChem : 2442
UniChem : OJGDCBLYJGHCIH-UHFFFAOYSA-N
Target
Families : Bromhexine ligand of proteins in family
Pancreatic_lipase
Protein :
human-PNLIP
References (9)
| Title : Combining kinetics and in silico approaches to evaluate bromhexine as an anti-pancreatic lipase agent for obesity management - Gholami_2025_Sci.Rep_15_18420 |
| Author(s) : Gholami A , Minai-Tehrani D , Eriksson LA |
| Ref : Sci Rep , 15 :18420 , 2025 |
| Abstract : |
| PubMedSearch : Gholami_2025_Sci.Rep_15_18420 |
| PubMedID: 40419556 |
| Title : Combining kinetics and in silico approaches to evaluate bromhexine as an anti-pancreatic lipase agent for obesity management - Gholami_2025_Sci.Rep_15_18420 |
| Author(s) : Gholami A , Minai-Tehrani D , Eriksson LA |
| Ref : Sci Rep , 15 :18420 , 2025 |
| Abstract : |
| PubMedSearch : Gholami_2025_Sci.Rep_15_18420 |
| PubMedID: 40419556 |
| Title : Combining kinetics and in silico approaches to evaluate bromhexine as an anti-pancreatic lipase agent for obesity management - Gholami_2025_Sci.Rep_15_18420 |
| Author(s) : Gholami A , Minai-Tehrani D , Eriksson LA |
| Ref : Sci Rep , 15 :18420 , 2025 |
| Abstract : |
| PubMedSearch : Gholami_2025_Sci.Rep_15_18420 |
| PubMedID: 40419556 |
| Title : Discovery of novel inhibitors for Pseudomonas aeruginosa lipase enzyme from in silico and in vitro studies - Gholami_2024_J.Biomol.Struct.Dyn_42_2197 |
| Author(s) : Gholami A , Minai-Tehrani D , Farewell A , Eriksson LA |
| Ref : J Biomol Struct Dyn , 42 :2197 , 2024 |
| Abstract : |
| PubMedSearch : Gholami_2024_J.Biomol.Struct.Dyn_42_2197 |
| PubMedID: 37098781 |
| Title : Discovery of novel inhibitors for Pseudomonas aeruginosa lipase enzyme from in silico and in vitro studies - Gholami_2024_J.Biomol.Struct.Dyn_42_2197 |
| Author(s) : Gholami A , Minai-Tehrani D , Farewell A , Eriksson LA |
| Ref : J Biomol Struct Dyn , 42 :2197 , 2024 |
| Abstract : |
| PubMedSearch : Gholami_2024_J.Biomol.Struct.Dyn_42_2197 |
| PubMedID: 37098781 |
| Title : Discovery of novel inhibitors for Pseudomonas aeruginosa lipase enzyme from in silico and in vitro studies - Gholami_2024_J.Biomol.Struct.Dyn_42_2197 |
| Author(s) : Gholami A , Minai-Tehrani D , Farewell A , Eriksson LA |
| Ref : J Biomol Struct Dyn , 42 :2197 , 2024 |
| Abstract : |
| PubMedSearch : Gholami_2024_J.Biomol.Struct.Dyn_42_2197 |
| PubMedID: 37098781 |
| Title : Bromhexine and its inhibitory effect on lipase - kinetics and structural study - Gholami_2020_Arch.Physiol.Biochem__1 |
| Author(s) : Gholami A , Minai-Tehrani D , Eftekhar F |
| Ref : Arch Physiol Biochem , :1 , 2020 |
| Abstract : |
| PubMedSearch : Gholami_2020_Arch.Physiol.Biochem__1 |
| PubMedID: 32633559 |
| Title : Bromhexine and its inhibitory effect on lipase - kinetics and structural study - Gholami_2020_Arch.Physiol.Biochem__1 |
| Author(s) : Gholami A , Minai-Tehrani D , Eftekhar F |
| Ref : Arch Physiol Biochem , :1 , 2020 |
| Abstract : |
| PubMedSearch : Gholami_2020_Arch.Physiol.Biochem__1 |
| PubMedID: 32633559 |
| Title : Bromhexine and its inhibitory effect on lipase - kinetics and structural study - Gholami_2020_Arch.Physiol.Biochem__1 |
| Author(s) : Gholami A , Minai-Tehrani D , Eftekhar F |
| Ref : Arch Physiol Biochem , :1 , 2020 |
| Abstract : |
| PubMedSearch : Gholami_2020_Arch.Physiol.Biochem__1 |
| PubMedID: 32633559 |