Bromopyrazolo-pyrimidine-carbonitrile
IC50 for eleel AChE 43.75 +/- 6.29 (nM); IC50 for horse BChE 175.00 +/- 4.11 (nM)
General
Type : Pyrimidine, Pyrazol, Cyanide
Chemical_Nomenclature : 6-bromopyrazolo[1,5-a]pyrimidine-3-carbonitrile
Canonical SMILES : C1=C(C=NC2=C(C=NN21)C#N)Br
InChI : InChI=1S\/C7H3BrN4\/c8-6-3-10-7-5(1-9)2-11-12(7)4-6\/h2-4H
InChIKey : IDYCEZBYNPADDN-UHFFFAOYSA-N
Other name(s) : DTXSID20346710 || RefChem:541269 || Compound 1 || SCHEMBL1991834
MW : 223.03
Formula : C7H3BrN4
CAS_number : 352637-44-6
PubChem : 614285
UniChem : IDYCEZBYNPADDN-UHFFFAOYSA-N
Target
Families : Bromopyrazolo-pyrimidine-carbonitrile ligand of proteins in family
ACHE
Protein :
human-ACHE
References (1)
| Title : Evaluation of pyrimidine-based compounds as AChE and BChE inhibitors: in vitro inhibition, molecular modeling, and statistical evaluation - Alim_2026_Naunyn.Schmiedebergs.Arch.Pharmacol__ |
| Author(s) : Alim Z , Demir Y |
| Ref : Naunyn Schmiedebergs Arch Pharmacol , : , 2026 |
| Abstract : |
| PubMedSearch : Alim_2026_Naunyn.Schmiedebergs.Arch.Pharmacol__ |
| PubMedID: 42024241 |