Butoxy-methyl-oxadiazol-aniline-4a
AChE inhibition IC50 0.0158 microM
General
Type : Benzimidazole, Oxadiazol
Chemical_Nomenclature : 6-butoxy-4-(3-methyl-1,2,4-oxadiazol-5-yl)aniline
Canonical SMILES : C1(=C(C=CC(=C1)C2=NC(=NO2)C)N)OCCCC
InChI : InChI=1S\/C13H17N3O2\/c1-3-4-7-17-12-8-10(5-6-11(12)14)13-15-9(2)16-18-13\/h5-6,8H,3-4,7,14H2,1-2H3
InChIKey : CXVRQICJWIZHEA-UHFFFAOYSA-N
Other name(s) : 4a
Target
Families : Butoxy-methyl-oxadiazol-aniline-4a ligand of proteins in family
ACHE
Protein :
human-ACHE
References (1)
| Title : Design, synthesis, and biological evaluation of 1,2,4-oxadiazole-based derivatives as multitarget anti-Alzheimer agents - Ayoup_2024_RSC.Med.Chem_15_2080 |
| Author(s) : Ayoup MS , Barakat MR , Abdel-Hamid H , Emam E , Al-Faiyz YS , Masoud AA , Ghareeb DA , Sonousi A , Kassab AE |
| Ref : RSC Med Chem , 15 :2080 , 2024 |
| Abstract : |
| PubMedSearch : Ayoup_2024_RSC.Med.Chem_15_2080 |
| PubMedID: 38911158 |