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Oxadiazol

General

Building block for many inhibitors of enzymes. (Benzoxadiazole compounds are separated in another type entry)
Inhibitor Main targeted enzyme families Type Structure
Phenyl-phenylpyridin-oxadiazol-cpd5a ACHE BCHE Oxadiazol Multitarget Pyridine
X20348 Thioesterase Oxadiazol Sulfur Compound Sulfonamide
JJ-OX-004 6_AlphaBeta_hydrolase Oxadiazolone Oxadiazol Alkyne
AKOS021877793 Carboxylesterase Carb_B_Chordata Triazol Oxadiazol
IL8 Thioesterase Carboxamide Oxadiazol Azetidin
IKG Thioesterase Carboxamide Cyanide Oxadiazol Azetidin
IJJ Thioesterase Carboxamide Oxadiazol Azetidin
Antibacterial-agent-136 Monoglyceridelipase_lysophospholip Hormone-sensitive_lipase_like 6_AlphaBeta_hydrolase Oxadiazol Carbamate
Antibact-product-Oxadiazolone-cp3 6_AlphaBeta_hydrolase Oxadiazol Carbamate
iBpPPOX A85-Mycolyl-transferase Oxadiazol Phenoxyphenyl
BemPPOX Acidic_Lipase Oxadiazol Phenoxyphenyl
Compound5d-Benzylpiperidine-Phenyl-oxadiazol-thiol ACHE anti-Abeta-aggregation Sulfur Compound BACE1-inhibitor Piperidine Multitarget Carboxamide Oxadiazol Derivative of Donepezil Cyanide
ZINC22029744 ACHE BCHE Multitarget Sulfur Compound Derivative of Donepezil BACE1-inhibitor Piperazine Oxadiazol
Butoxy-methyl-oxadiazol-aniline-4a ACHE Benzimidazole Oxadiazol
Cpd20-Benzimidazol-Oxadiazol BCHE Benzimidazole Oxadiazol Cyanide Carboxamide
S16-1029 BCHE Benzimidazole Oxadiazol Morpholine Carboxamide
Tetrabenzyl-D-glucosamine-oxadiazole-6i ACHE Oxadiazol Carbohydrate Glycoside
Difluorophenyl-pyridin-piperazin-1,3,4-oxadiazole-49 ACHE BCHE Oxadiazol Pyridine Piperazine
4-aminopyridine-1,3,4-oxadiazole-9 ACHE Oxadiazol Pyridine
5-pyrid-3-yl-1,3,4-oxadiazole-5e ACHE BCHE Oxadiazol Pyridine
Fragment-201 Pectinacetylesterase-Notum Fragment inhibitor of Notum Piperidine Oxadiazol
Maybridge_4 Pectinacetylesterase-Notum Fragment inhibitor of Notum Hydrazide Oxadiazol tert-Butyl
6KZ-4CIA Carboxypeptidase_S10 Carboxamide Morpholine Oxadiazol
P1-benzoxadiazole-fluorogenic-ligand Haloalkane_dehalogenase-HLD2 Fluorescent Probe Sulfur Compound Sulfonamide Benzoxadiazole
Fragment-063-notum-screen Pectinacetylesterase-Notum Urea derivative Fragment inhibitor of Notum Benzoxadiazole
S06-1011 BCHE Quinoline Imidazole Oxadiazol Benzimidazole
SCHEMBL21776992 Pectinacetylesterase-Notum Trifluoro Oxadiazolone Oxadiazol
8012-9656 BCHE Quinoline Imidazole Oxadiazol Benzimidazole
JUB BCHE Piperidine Piperazine NBD-nitro-benzoxadiazol-fluorescent Benzoxadiazole Sulfur Compound Sulfonamide Naphthalen
SCHEMBL15589912 Lipoprotein_Lipase Benzothiazol Sulfur Compound Thiazolidine Morpholine Oxadiazol Sulfonyl
NBD-5-acylcholine ACHE Trimethylammonium Analogue of substrate NBD-nitro-benzoxadiazol-fluorescent Benzoxadiazole
CHEMBL1615216 Epoxide_hydrolase Piperidine Urea derivative Cyclopropyl Carboxamide Oxadiazol
Flouroolefin-1 DPP4N_Peptidase_S9 Sulfur Compound Pyrrolidine Cyclopropyl Oxadiazol
Flouroolefin-2 DPP4N_Peptidase_S9 Sulfur Compound Cyclopropyl Oxadiazol Sulfonyl
1,3,4-oxadiazolyl-ketone-18h DPP4N_Peptidase_S9 Pyrrolidine Ketone Oxadiazol tert-Butyl
3TP DPP4N_Peptidase_S9 Pyrrolidine Sulfur Compound Oxadiazol Sulfonyl
6AX1-cp3 Monoglyceridelipase_lysophospholip Halo ketone Trifluoro Carbamate Azetidin Oxadiazol
Ala-Tboda Proline_iminopeptidase Peptide Oxadiazol tert-Butyl
Sar-Tboda Proline_iminopeptidase Peptide Oxadiazol tert-Butyl
Pro-Tboda Proline_iminopeptidase Peptide Pyrrolidine Oxadiazol tert-Butyl
CAY10499 Monoglyceridelipase_lysophospholip Carb_B_Chordata ABHD6-Lip Lipase_3 Hormone-sensitive_lipase_like Carbamate Oxadiazol
CHEMBL1684295 Prolylcarboxypeptidase Pyrrolidine Imidazole Pyridine Oxadiazol Piperidine Benzimidazole
Indol-adamantyl-carbamate-Nitrobenzooxadiazol-Cpd20 DPP4N_Peptidase_S9 Gliptin Adamantyl Carbamate Indole Oxadiazol NBD-nitro-benzoxadiazol-fluorescent Benzoxadiazole
NBD-CP Organophosphate ABPP-Probe NBD-nitro-benzoxadiazol-fluorescent Benzoxadiazole pNP Phenanthrene
NBD-TG Hormone-sensitive_lipase_like Monoglyceridelipase_lysophospholip ABHD11-Acetyl_transferase Triacylglycerol NBD-nitro-benzoxadiazol-fluorescent ABPP-Probe pNP Benzoxadiazole
NBD-HE-HP Hormone-sensitive_lipase_like Carb_B_Chordata Monoglyceridelipase_lysophospholip A85-EsteraseD-FGH ABHD11-Acetyl_transferase LYsophospholipase_carboxylesterase PPase_methylesterase_euk ACPH_Peptidase_S9 CGI-58_ABHD5_ABHD4 Bacterial_lip_FamI.2 Lipase_3 Carb_B_Arthropoda Juvenile_hormone_esterase S9N_PPCE_Peptidase_S9 Organophosphate ABPP-Probe NBD-nitro-benzoxadiazol-fluorescent pNP Benzoxadiazole
NBD-AE-MPF ACHE Organophosphate ABPP-Probe NBD-nitro-benzoxadiazol-fluorescent Benzoxadiazole
NBD-P-MPF ACHE Organophosphate ABPP-Probe NBD-nitro-benzoxadiazol-fluorescent Benzoxadiazole
NBD-AP-MPF ACHE Organophosphate ABPP-Probe NBD-nitro-benzoxadiazol-fluorescent Benzoxadiazole
Compound-9368 Hormone-sensitive_lipase_like Lipase_3 Oxadiazol
MPOX Acidic_Lipase Oxadiazolone Oxadiazol Lipase inhibitor
MpPPOX Acidic_Lipase Oxadiazolone Oxadiazol Lipase inhibitor Phenoxyphenyl
MmPPOX Acidic_Lipase Hormone-sensitive_lipase_like ABHD16 Oxadiazolone Oxadiazol Lipase inhibitor Phenoxyphenyl
Metoxadiazone Acidic_Lipase Oxadiazolone Oxadiazol Lipase inhibitor
DBOX Acidic_Lipase Oxadiazolone Oxadiazol Lipase inhibitor Benzofuran