CHEMBL1088377
BChE IC50 1.8 microM; NMDA receptor IC50 1.8 microM; AChE IC50 86 microM
General
Type : beta-carboline, Multitarget
Chemical_Nomenclature : 2-[12-(9H-pyrido[3,4-b]indol-2-ium-2-yl)dodecyl]-9H-pyrido[3,4-b]indol-2-ium
Canonical SMILES : C1=CC=C2C(=C1)C3=C(N2)C=[N+](C=C3)CCCCCCCCCCCC[N+]4=CC5=C(C=C4)C6=CC=CC=C6N5
InChI : InChI=1S\/C34H38N4\/c1(3-5-7-13-21-37-23-19-29-27-15-9-11-17-31(27)35-33(29)25-37)2-4-6-8-14-22-38-24-20-30-28-16-10-12-18-32(28)36-34(30)26-38\/h9-12,15-20,23-26H,1-8,13-14,21-22H2\/p+2
InChIKey : VCJGRMVHAYBWRI-UHFFFAOYSA-P
Other name(s) : CHEMBL1198993 || BDBM50317182 || 2-[12-(beta-Carboline-2-ium-2-yl)dodecyl]-beta-carboline-2-ium dibromide
MW : 504.7g\/mol
Formula : C34H40N4+2
CAS_number :
PubChem : 46222895\
UniChem : VCJGRMVHAYBWRI-UHFFFAOYSA-P
Target
References (1)
| Title : beta-Carboline as a Privileged Scaffold for Multitarget Strategies in Alzheimer's Disease Therapy - Beato_2021_J.Med.Chem__ |
| Author(s) : Beato A , Gori A , Boucherle B , Peuchmaur M , Haudecoeur R |
| Ref : Journal of Medicinal Chemistry , : , 2021 |
| Abstract : |
| PubMedSearch : Beato_2021_J.Med.Chem__ |
| PubMedID: 33528252 |