CHEMBL184251
eelAChE IC50 0.33 microM
General
Type :
Chemical_Nomenclature : 11-benzyl-5-[(3,4-dimethoxyphenyl)methyl-methylamino]-4-oxa-8-thia-6,11-diazatricyclo[7.4.0.02,7]trideca-1(9),2(7),5-trien-3-one
Canonical SMILES : CN(CC1=CC(=C(C=C1)OC)OC)C2=NC3=C(C4=C(S3)CN(CC4)CC5=CC=CC=C5)C(=O)O2
InChI : InChI=1S\/C26H27N3O4S\/c1-28(14-18-9-10-20(31-2)21(13-18)32-3)26-27-24-23(25(30)33-26)19-11-12-29(16-22(19)34-24)15-17-7-5-4-6-8-17\/h4-10,13H,11-12,14-16H2,1-3H3
InChIKey : LPYHCNUDPSUTOZ-UHFFFAOYSA-N
Other name(s) : BDBM50179328 || 7-benzyl-5,6,7,8-tetrahydro-2-[N-3,4-dimethoxy-benzyl-N-methyl-amino]-4H-pyrido[4'',3'':4,5]thieno[2,3-d][1,3]oxazin-4-one || Compound 21
MW : 477.6
Formula : C26H27N3O4S
CAS_number :
PubChem : 11648613
UniChem : LPYHCNUDPSUTOZ-UHFFFAOYSA-N
Target
Families : CHEMBL184251 ligand of proteins in family
ACHE
References (1)
| Title : Synthesis of tricyclic 1,3-oxazin-4-ones and kinetic analysis of cholesterol esterase and acetylcholinesterase inhibition - Pietsch_2005_J.Med.Chem_48_8270 |
| Author(s) : Pietsch M , Gutschow M |
| Ref : Journal of Medicinal Chemistry , 48 :8270 , 2005 |
| Abstract : |
| PubMedSearch : Pietsch_2005_J.Med.Chem_48_8270 |
| PubMedID: 16366609 |