| Title : Aminoalkoxy-substituted coumarins: Synthesis and evaluation for reactivation of inhibited human acetylcholinesterase - Elsinghorst_2022_Arch.Pharm.(Weinheim)__e2200208 |
| Author(s) : Elsinghorst PW , Wille T , Baric D , Mertens MD , Baumann M , Kuppers J , Gutschow M |
| Ref : Arch Pharm (Weinheim) , :e2200208 , 2022 |
| PubMedID: 35876340 |
| Title : The Chemotype of Chromanones as a Privileged Scaffold for Multineurotarget Anti-Alzheimer Agents - Keuler_2022_ACS.Pharmacol.Transl.Sci_5_1097 |
| Author(s) : Keuler T , Lemke C , Elsinghorst PW , Iriepa I , Chioua M , Martinez-Grau MA , Beadle CD , Vetman T , Lopez-Munoz F , Wille T , Bartz U , Deuther-Conrad W , Marco-Contelles J , Gutschow M |
| Ref : ACS Pharmacol Transl Sci , 5 :1097 , 2022 |
| PubMedID: 36407962 |
| Title : Studies on the affinity of 6-[(n-(cyclo)aminoalkyl)oxy]-4H-chromen-4-ones for sigma 1\/2 receptors - Deuther-Conrad_2021_RSC.Med.Chem_12_1000 |
| Author(s) : Deuther-Conrad W , Diez-Iriepa D , Iriepa I , Lopez-Munoz F , Martinez-Grau MA , Gutschow M , Marco-Contelles J |
| Ref : RSC Med Chem , 12 :1000 , 2021 |
| PubMedID: 34223165 |
| Title : omega-Quinazolinonylalkyl aryl ureas as reversible inhibitors of monoacylglycerol lipase - Dato_2019_Bioorg.Chem__103352 |
| Author(s) : Dato FM , Neudorfl JM , Gutschow M , Goldfuss B , Pietsch M |
| Ref : Bioorg Chem , :103352 , 2019 |
| PubMedID: 31668797 |
| Gene_locus related to this paper: human-MGLL |
| Title : Chromenones as Multineurotargeting Inhibitors of Human Enzymes - Lemke_2019_ACS.Omega_4_22161 |
| Author(s) : Lemke C , Christmann J , Yin J , Alonso JM , Serrano E , Chioua M , Ismaili L , Martinez-Grau MA , Beadle CD , Vetman T , Dato FM , Bartz U , Elsinghorst PW , Pietsch M , Muller CE , Iriepa I , Wille T , Marco-Contelles J , Gutschow M |
| Ref : ACS Omega , 4 :22161 , 2019 |
| PubMedID: 31891098 |
| Title : omega-Phthalimidoalkyl Aryl Ureas as Potent and Selective Inhibitors of Cholesterol Esterase - Dato_2018_ChemMedChem_13_1833 |
| Author(s) : Dato FM , Sheikh M , Uhl RZ , Schuller AW , Steinkruger M , Koch P , Neudorfl JM , Gutschow M , Goldfuss B , Pietsch M |
| Ref : ChemMedChem , 13 :1833 , 2018 |
| PubMedID: 30004170 |
| Title : A novel fluorogenic probe for the investigation of free thiols: Application to kinetic measurements of acetylcholinesterase activity - Mertens_2016_Toxicol.Lett_244_161 |
| Author(s) : Mertens MD , Bierwisch A , Li T , Gutschow M , Thiermann H , Wille T , Elsinghorst PW |
| Ref : Toxicol Lett , 244 :161 , 2016 |
| PubMedID: 26494253 |
| Title : Novel structural hybrids of pyrazolobenzothiazines with benzimidazoles as cholinesterase inhibitors - Aslam_2014_Eur.J.Med.Chem_78C_106 |
| Author(s) : Aslam S , Zaib S , Ahmad M , Gardiner JM , Ahmad A , Hameed A , Furtmann N , Gutschow M , Bajorath J , Iqbal J |
| Ref : Eur Journal of Medicinal Chemistry , 78C :106 , 2014 |
| PubMedID: 24681070 |
| Title : Synthesis and evaluation of 2-(1H-indol-3-yl)-4-phenylquinolines as inhibitors of cholesterol esterase - Muscia_2014_Bioorg.Med.Chem.Lett_24_1545 |
| Author(s) : Muscia GC , Hautmann S , Buldain GY , Asis SE , Gutschow M |
| Ref : Bioorganic & Medicinal Chemistry Lett , 24 :1545 , 2014 |
| PubMedID: 24556381 |
| Title : Hyperbolic mixed-type inhibition of acetylcholinesterase by tetracyclic thienopyrimidines - Tanarro_2011_J.Enzyme.Inhib.Med.Chem_26_350 |
| Author(s) : Tanarro CM , Gutschow M |
| Ref : J Enzyme Inhib Med Chem , 26 :350 , 2011 |
| PubMedID: 20807084 |
| Title : A hydrazide linker strategy for heterobivalent compounds as ortho- and allosteric ligands of acetylcholine-binding proteins - Elsinghorst_2011_Curr.Top.Med.Chem_11_2731 |
| Author(s) : Elsinghorst PW , Hartig W , Gundisch D , Mohr K , Trankle C , Gutschow M |
| Ref : Curr Top Med Chem , 11 :2731 , 2011 |
| PubMedID: 22039876 |
| Title : New cholesterol esterase inhibitors based on rhodanine and thiazolidinedione scaffolds - Heng_2011_Bioorg.Med.Chem_19_7453 |
| Author(s) : Heng S , Tieu W , Hautmann S , Kuan K , Pedersen DS , Pietsch M , Gutschow M , Abell AD |
| Ref : Bioorganic & Medicinal Chemistry , 19 :7453 , 2011 |
| PubMedID: 22075233 |
| Title : In vivo labelling of hippocampal beta-amyloid in triple-transgenic mice with a fluorescent acetylcholinesterase inhibitor released from nanoparticles - Hartig_2010_Eur.J.Neurosci_31_99 |
| Author(s) : Hartig W , Kacza J , Paulke BR , Grosche J , Bauer U , Hoffmann A , Elsinghorst PW , Gutschow M |
| Ref : European Journal of Neuroscience , 31 :99 , 2010 |
| PubMedID: 20092557 |
| Title : Kinetics of inhibition of acetylcholinesterase in the presence of acetonitrile - Pietsch_2009_FEBS.J_276_2292 |
| Author(s) : Pietsch M , Christian L , Inhester T , Petzold S , Gutschow M |
| Ref : Febs J , 276 :2292 , 2009 |
| PubMedID: 19292865 |
| Title : A gorge-spanning, high-affinity cholinesterase inhibitor to explore beta-amyloid plaques - Elsinghorst_2009_Org.Biomol.Chem_7_3940 |
| Author(s) : Elsinghorst PW , Hartig W , Goldhammer S , Grosche J , Gutschow M |
| Ref : Org Biomol Chem , 7 :3940 , 2009 |
| PubMedID: 19763296 |
| Title : Synthesis and elastase-inhibiting activity of 2-pyridinyl-isothiazol-3(2H)-one 1,1-dioxides - Eilfeld_2008_Bioorg.Med.Chem_16_8127 |
| Author(s) : Eilfeld A , Gonzalez Tanarro CM , Frizler M , Sieler J , Schulze B , Gutschow M |
| Ref : Bioorganic & Medicinal Chemistry , 16 :8127 , 2008 |
| PubMedID: 18701300 |
| Title : First gallamine-tacrine hybrid: design and characterization at cholinesterases and the M2 muscarinic receptor - Elsinghorst_2007_J.Med.Chem_50_5685 |
| Author(s) : Elsinghorst PW , Cieslik JS , Mohr K , Trankle C , Gutschow M |
| Ref : Journal of Medicinal Chemistry , 50 :5685 , 2007 |
| PubMedID: 17944454 |
| Title : Novel heterobivalent tacrine derivatives as cholinesterase inhibitors with notable selectivity toward butyrylcholinesterase - Elsinghorst_2006_J.Med.Chem_49_7540 |
| Author(s) : Elsinghorst PW , Tanarro CM , Gutschow M |
| Ref : Journal of Medicinal Chemistry , 49 :7540 , 2006 |
| PubMedID: 17149883 |
| Title : Synthesis of tricyclic 1,3-oxazin-4-ones and kinetic analysis of cholesterol esterase and acetylcholinesterase inhibition - Pietsch_2005_J.Med.Chem_48_8270 |
| Author(s) : Pietsch M , Gutschow M |
| Ref : Journal of Medicinal Chemistry , 48 :8270 , 2005 |
| PubMedID: 16366609 |
| Title : Alternate substrate inhibition of cholesterol esterase by thieno[2,3-d][1,3]oxazin-4-ones - Pietsch_2002_J.Biol.Chem_277_24006 |
| Author(s) : Pietsch M , Gutschow M |
| Ref : Journal of Biological Chemistry , 277 :24006 , 2002 |
| PubMedID: 11959857 |