CHEMBL5429715
3e BChE IC50 77.87 +/- 0.41 microg/mL; AChE IC50 4.41 +/- 0.53 microg/mL
General
Type : Pyrazole, Chromen, Coumarin
Chemical_Nomenclature : 3-(5-methyl-1H-pyrazol-3-yl)-6-nitrochromen-2-one
Canonical SMILES : CC1=CC(=NN1)C2=CC3=C(C=CC(=C3)[N+](=O)[O-])OC2=O
InChI : InChI=1S\/C13H9N3O4\/c1-7-4-11(15-14-7)10-6-8-5-9(16(18)19)2-3-12(8)20-13(10)17\/h2-6H,1H3,(H,14,15)
InChIKey : RHHHFDPVCAXIJX-UHFFFAOYSA-N
Other name(s) : 6-nitro-3-(5-methyl-1H-pyrazol-3-yl)-2H-chromen-2-one || Compound 3e || BDBM50625996
MW : 271.23
Formula : C13H9N3O4
CAS_number :
PubChem : 172462235
UniChem : RHHHFDPVCAXIJX-UHFFFAOYSA-N
Target
References (1)
| Title : New Coumarin-Pyrazole hybrids: Synthesis, Docking studies and Biological evaluation as potential cholinesterase inhibitors - Benazzouz-Touami_2022_J.Mol.Struct_1249_131591 |
| Author(s) : Benazzouz-Touami A , Chouh A , Halit S , Terrachet-Bouaziz S , Makhloufi-Chebli M , Ighil-Ahriz K , Silva AMS |
| Ref : J Mol Struct , 1249 :131591 , 2022 |
| Abstract : |
| PubMedSearch : Benazzouz-Touami_2022_J.Mol.Struct_1249_131591 |
| PubMedID: 35221376 |