Pyrazole

General

Pyrazole is an organic compound with the formula C3H3N2H. It is a heterocycle characterized by a 5-membered ring of three carbon atoms and two adjacent nitrogen atoms

Inhibitor	Main targeted enzyme families	Type
Benzylpiperazinephenyl-phenyl-pyrazol-cpd48	BCHE	Multitarget BACE1-inhibitor anti-Abeta-aggregation Piperazin Pyrazole
DPP4-inhibitor-Cpd46	DPP4N_Peptidase_S9	Sulfur Compound Pyrazole Pyrimidine Pyrrolidine
HY-155961	DPP4N_Peptidase_S9	Thiazolidine Sulfur Compound Pyrazole Pyrrolidine
Nitrophenyl-thiophen-morpholinyl-phenyl-pyrazoline-2l	ACHE	Sulfur Compound Pyrazole Morpholine Thiophen
CHEMBL4437989	Monoglyceridelipase_lysophospholip	Piperazine Pyrazole Cyanide
CHEMBL4559005	Monoglyceridelipase_lysophospholip	Naphthalen Piperazine Pyrazole Cyanide
MGLL-IN-Cpd118	Monoglyceridelipase_lysophospholip	Triazol Azaspiro Trifluoro Pyrazole
5ISM-6DG	DPP4N_Peptidase_S9	Pyrimidine Pyrrolidine Pyrazole
Pyrazolopyridine-Cpd37	Monoglyceridelipase_lysophospholip	Pyridine Pyrazole
Cofrogliptin	DPP4N_Peptidase_S9	Gliptin Trifluoro Pyrazole Sulfonamide Sulfur Compound
Diclofenac-derivative-39	ACHE	Monoamine-oxidase-inhibitor Multitarget 5-Lipoxygenase inhibitor Sulfur Compound Sulfonamide Pyrazole
Fragment-863	Pectinacetylesterase-Notum	Fragment inhibitor of Notum Pyrazole
Fragment-886	Pectinacetylesterase-Notum	Fragment inhibitor of Notum Piperidine Pyrazole
Fragment-067	Pectinacetylesterase-Notum	Fragment inhibitor of Notum Pyrimidine Pyrazole
Fragment-174	Pectinacetylesterase-Notum	Fragment inhibitor of Notum Pyrazole
Fragment-193	Pectinacetylesterase-Notum	Fragment inhibitor of Notum Pyrazole
ARUK3003710	Pectinacetylesterase-Notum	Fragment inhibitor of Notum Pyrazole
PTUPB	Epoxide_hydrolase	Multitarget Trifluoro Urea derivative Sulfur Compound Sulfonamide Pyrazole
CHEMBL3233605-S0D-3WK7	Epoxide_hydrolase	Benzimidazole Pyrazole
CHEMBL3402236-49P-4Y2S	Epoxide_hydrolase	Trifluoro Pyrazole
CHEMBL3402239-4A5-4Y2V	Epoxide_hydrolase	Acetate Cyclopropyl Pyrazole
Pyrazolone-27	Carb_B_Chordata	Pyrazole
ABD957	ABHD17-depalmitoylase	Trifluoro Sulfur Compound Sulfonamide Piperazine Pyrazole Azabicyclo
CID155803786	ABHD17-depalmitoylase	Piperazine Trifluoro Sulfur Compound Sulfonamide Morpholine Pyrazole
CID155803792	ABHD17-depalmitoylase LYsophospholipase_carboxylesterase	Piperazine Trifluoro Sulfur Compound Sulfonamide Morpholine Pyrazole
CID155803782	ABHD17-depalmitoylase LYsophospholipase_carboxylesterase	Piperazine Trifluoro Sulfur Compound Sulfonamide Morpholine Pyrazole
CID155803778	ABHD17-depalmitoylase LYsophospholipase_carboxylesterase	Piperazine Sulfur Compound Sulfonamide Pyrazole
Difluoromethyl-ketone-BT7	ACHE	Ketone Pyrazole
CHEMBL3402234	Epoxide_hydrolase	Pyrazole
Anagliptin	DPP4N_Peptidase_S9	Drug Cyanide Pyrrolidine Gliptin Pyrimidine Carboxamide Pyrazole
CHEMBL2147710	DPP4N_Peptidase_S9	Trifluoro Pyrrolidine Thiazolidine Sulfur Compound Pyrazole
PF-06795071	Monoglyceridelipase_lysophospholip	Trifluoro Carbamate PET probe Pyrazole Azabicyclo
CHEMBL1234565	Epoxide_hydrolase	Pyridine Nicotinamide Carboxamide Pyrazole
Teneligliptin	DPP4N_Peptidase_S9	Drug Piperazine Pyrrolidine Gliptin Thiazolidine Sulfur Compound Pyrazole
Flupyrazofos	ACHE	Insecticide Sulfur Compound Organophosphate Pyrazole
MGL-Inhibitor-26	Monoglyceridelipase_lysophospholip	Piperidine Carboxamide Pyrazole
Omarigliptin	DPP4N_Peptidase_S9	Sulfur Compound Gliptin Pyrazole
CHEMBL3145341	Carboxypeptidase_S10	Carboxamide Pyrazole Propionate
CHEMBL2171392	Carboxypeptidase_S10	Carboxamide Pyrazole
QST-0837	Monoglyceridelipase_lysophospholip	PET probe Carbamate Trifluoro Azetidin Pyrazole
Pyraclofos	ACHE	Organophosphate Insecticide Sulfur Compound Pyrazole
hAChE-IN-6	BCHE ACHE	Pyridine Pyrazole GSK-3 kinase inhibitor Multitarget
Pyrazophos	ACHE	Organophosphate Insecticide Sulfur Compound Pyrazole
Pyrazothion	ACHE	Organophosphate Sulfur Compound Organothiophosphate Pyrazole
Pyrazoxon	ACHE	Organophosphate Pyrazole
Pyridaphenthion	ACHE	Organophosphate Insecticide Sulfur Compound Pyridazine Pyrazole