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Coumarin

General

Coumarin is derived from coumarou, the French word for the tonka bean. Some naturally occurring coumarin derivatives include umbelliferone (7-hydroxycoumarin), aesculetin (6,7-dihydroxycoumarin), herniarin (7-methoxycoumarin), psoralen and imperatorin
Inhibitor Main targeted enzyme families Type Structure
CHEMBL4586480 Triazol Alkyl linked bis-ligand Multitarget Coumarin Chromen
CHEMBL3322160 Acridine Derivative of Tacrine Alkyl linked bis-ligand Multitarget Coumarin Chromen
Diethylamino-chromen-thiazol-acetamide Thiazole Sulfur Compound Coumarin Chromen
AP2238 ACHE Multitarget Coumarin anti-Abeta-aggregation Chromen
Coumarin-phosphazide-Cpd8b ACHE BCHE Multitarget Coumarin anti-Abeta-aggregation Chromen
Coumarin-dimethoxyphenyl-methylpiperidine-carboxamise-cpd3b ACHE Coumarin Piperidine Carboxamide Derivative of Donepezil Chromen
3-aminocoumarin-N-benzylpyridinium-9h ACHE Coumarin Pyridine Chromen
JCP276 Coumarin Urea derivative Chromen
Coumarin-Pyridine-3f ACHE BCHE Coumarin Pyridine Chromen
7QAK-Cpd1 ACHE Monoamine-oxidase-inhibitor Multitarget Coumarin Chromen
7QB4-Cpd2 ACHE Monoamine-oxidase-inhibitor Multitarget Coumarin Chromen Derivative of Donepezil
ABP-JCP251-bT Hormone-sensitive_lipase_like Coumarin Chromen Triazol ABPP-Probe Boron compound Boranuidatricyclo BODIPY-derivative Fluorescent Probe
JCP251 Hormone-sensitive_lipase_like A85-EsteraseD-FGH Coumarin Chromen
PE154 ACHE BCHE Derivative of Tacrine Multitarget Hydrazide Coumarin Chromen
CHEMBL440526 BCHE ACHE Multitarget Carbamate Coumarin Chromen
6RUA-3a BCHE Sulfur Compound Sulfonamide Coumarin Piperidine Carboxamide Naphthalen Chromen
JU5 BCHE Coumarin Piperidine Carboxamide Naphthalen Sulfur Compound Chromen
4-methylumbelliferyl-hexylphosphonate Canar_LipB Hormone-sensitive_lipase_like Organophosphate Coumarin Chromen
3-chloro-7-hydroxy-4-methylcoumarin BCHE ACHE Coumarin
7-hydroxy-4-methylcoumarin Coumarin Chromen Leaving group
Coumarinyl-ethyl-p-trifluoroacetamidophenylmethylphosphonate BCHE Trifluoro Organophosphate Halo ketone Coumarin Chromen
Coralox ACHE Coumarin Anthelmintic Insecticide Organophosphate Chromen
Coumaphos ACHE Coumarin Anthelmintic Insecticide Organophosphate Sulfur Compound Organothiophosphate
Scopoletin Coumarin Natural Chromen
Coumarin Coumarin Chromen
dMUP ACHE Organophosphate Coumarin Chromen
Methyl-DEUP Bacterial_lip_FamI.1 Organophosphate Coumarin Chromen
DEUP Cholesterol_esterase Hormone-sensitive_lipase_like Arylacetamide_deacetylase Carb_B_Arthropoda Organophosphate Coumarin Chromen
EMPC ACHE Organophosphate Coumarin Chromen
Haloxon ACHE Organophosphate Coumarin
EMP-MeCyC ACHE Cyanide Organophosphate Flu-OP Nerve Agent V-series Surrogate OP Coumarin
CMP-MeCyC ACHE Organophosphate Flu-OP Nerve Agent G-series Surrogate OP Coumarin Derivative of Sarin Chromen Cyanide
PMP-MeCyC ACHE Organophosphate Flu-OP Nerve Agent G-series Surrogate OP Coumarin Derivative of Soman Chromen Cyanide
IMP-MeCyC ACHE Organophosphate Flu-OP Nerve Agent G-series Surrogate OP Derivative of Sarin Chromen Coumarin Cyanide
AChE-IN-27 ACHE Coumarin Cyanide Chromen