Carvacrol-triazole-selanyl-naphthalen-Cpd18e
AChE IC50 75nM
General
Type : Carvacrol-Thymol, Organoselenium, Triazol, Naphthalen
Chemical_Nomenclature : 4-((5-isopropyl-2-methylphenoxy)methyl)-1-((naphthalen-2-ylselanyl)methyl)-1H-1,2,3-triazole
Canonical SMILES : C1(=CC(=CC=C1C)C(C)C)OCC4=C[N](C[Se]C2=CC=C3C(=C2)C=CC=C3)N=N4
InChI : InChI=1S\/C24H25N3OSe\/c1-17(2)20-9-8-18(3)24(13-20)28-15-22-14-27(26-25-22)16-29-23-11-10-19-6-4-5-7-21(19)12-23\/h4-14,17H,15-16H2,1-3H3
InChIKey : DQVUMCXVBRRTGA-UHFFFAOYSA-N
Other name(s) : Compound 18e
Target
Families : Carvacrol-triazole-selanyl-naphthalen-Cpd18e ligand of proteins in family
ACHE
Protein :
human-ACHE
References (1)
| Title : Multifunctional Carvacrol-based Organoselenium hybrids as anticholinesterase and antioxidant candidates for Alzheimer's therapy - Gomes_2025_Bioorg.Med.Chem_132_118447 |
| Author(s) : Gomes LS , Schuler M , Giannini GB , Zapp E , de Oliveira AS , Nascimento V |
| Ref : Bioorganic & Medicinal Chemistry , 132 :118447 , 2025 |
| Abstract : |
| PubMedSearch : Gomes_2025_Bioorg.Med.Chem_132_118447 |
| PubMedID: 41166828 |