Compound-48.80

Compound 48/80 is a polymer produced by the condensation of N-methyl-p-methoxyphenethylamine with formaldehyde. It promotes histamine release, and in biochemical research, compound 48/80 is used to promote mast cell degranulation

General

Type : Polymer

Chemical_Nomenclature : Poly({2-methoxy-5-[2-(methylamino)ethyl]-1,3-phenylene}methylene)

Canonical SMILES :

InChI :

InChIKey :

Other name(s) : Compound 48\/80


MW :

Formula : (C11H15NO)n

CAS_number :

PubChem :

UniChem :

Target

Families : Compound-48.80 ligand of proteins in family
Duf_900

Protein :
barbk-a1usj6

References (9)

Title : Porin A and alpha\/beta-hydrolase are necessary and sufficient for hemolysis induced by Bartonella bacilliformis - Dichter_2025_Nat.Commun_16_10809
Author(s) : Dichter AA , Winklmeier F , Munteh D , Ballhorn W , Becker SA , Averhoff B , Bonig H , Goldman A , Garcia-Quintanilla M , Solis Cayo L , Tsukayama P , Kempf VAJ
Ref : Nat Commun , 16 :10809 , 2025
Abstract :
PubMedSearch : Dichter_2025_Nat.Commun_16_10809
PubMedID: 41315277
Gene_locus related to this paper: barbk-a1usj6

Title : Porin A and alpha\/beta-hydrolase are necessary and sufficient for hemolysis induced by Bartonella bacilliformis - Dichter_2025_Nat.Commun_16_10809
Author(s) : Dichter AA , Winklmeier F , Munteh D , Ballhorn W , Becker SA , Averhoff B , Bonig H , Goldman A , Garcia-Quintanilla M , Solis Cayo L , Tsukayama P , Kempf VAJ
Ref : Nat Commun , 16 :10809 , 2025
Abstract :
PubMedSearch : Dichter_2025_Nat.Commun_16_10809
PubMedID: 41315277
Gene_locus related to this paper: barbk-a1usj6

Title : Porin A and alpha\/beta-hydrolase are necessary and sufficient for hemolysis induced by Bartonella bacilliformis - Dichter_2025_Nat.Commun_16_10809
Author(s) : Dichter AA , Winklmeier F , Munteh D , Ballhorn W , Becker SA , Averhoff B , Bonig H , Goldman A , Garcia-Quintanilla M , Solis Cayo L , Tsukayama P , Kempf VAJ
Ref : Nat Commun , 16 :10809 , 2025
Abstract :
PubMedSearch : Dichter_2025_Nat.Commun_16_10809
PubMedID: 41315277
Gene_locus related to this paper: barbk-a1usj6

Title : Compound 48\/80 is a potent inhibitor of phospholipase C and a dual modulator of phospholipase A2 from human platelet - Bronner_1987_Biochim.Biophys.Acta_920_301
Author(s) : Bronner C , Wiggins C , Monte D , Marki F , Capron A , Landry Y , Franson RC
Ref : Biochimica & Biophysica Acta , 920 :301 , 1987
Abstract :
PubMedSearch : Bronner_1987_Biochim.Biophys.Acta_920_301
PubMedID: 3607084

Title : Compound 48\/80 is a potent inhibitor of phospholipase C and a dual modulator of phospholipase A2 from human platelet - Bronner_1987_Biochim.Biophys.Acta_920_301
Author(s) : Bronner C , Wiggins C , Monte D , Marki F , Capron A , Landry Y , Franson RC
Ref : Biochimica & Biophysica Acta , 920 :301 , 1987
Abstract :
PubMedSearch : Bronner_1987_Biochim.Biophys.Acta_920_301
PubMedID: 3607084

Title : Compound 48\/80 is a potent inhibitor of phospholipase C and a dual modulator of phospholipase A2 from human platelet - Bronner_1987_Biochim.Biophys.Acta_920_301
Author(s) : Bronner C , Wiggins C , Monte D , Marki F , Capron A , Landry Y , Franson RC
Ref : Biochimica & Biophysica Acta , 920 :301 , 1987
Abstract :
PubMedSearch : Bronner_1987_Biochim.Biophys.Acta_920_301
PubMedID: 3607084

Title : Molecular weight studies on the active constituents of compound 48-80 -
Author(s) : Read GW , Lenney JF
Ref : Journal of Medicinal Chemistry , 15 :320 , 1972
PubMedID: 5059219

Title : Molecular weight studies on the active constituents of compound 48-80 -
Author(s) : Read GW , Lenney JF
Ref : Journal of Medicinal Chemistry , 15 :320 , 1972
PubMedID: 5059219

Title : Molecular weight studies on the active constituents of compound 48-80 -
Author(s) : Read GW , Lenney JF
Ref : Journal of Medicinal Chemistry , 15 :320 , 1972
PubMedID: 5059219