barbk-a1usj6

Bartonella bacilliformis (strain ATCC 35685 / KC583) Putative lipoprotein

Comment

Carrions disease is endemic to the South American Andes and is characterized by fatal hemolytic anemia caused by Bartonella bacilliformis. Porin A and alpha\/beta-hydrolase (barbk-a1usj6) Duf_900 are necessary and sufficient for hemolysis induced by Bartonella bacilliformis. barbk-a1usj6 is the first protein with a link to function in the Duf_900 family

Relationship

Family : Duf_900

Block : X

Position in NCBI Life Tree : Bartonella bacilliformis

(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.)

> cellular organisms N E > Bacteria N E > Proteobacteria N E > Alphaproteobacteria N E > Rhizobiales N E > Bartonellaceae N E > Bartonella N E > Bartonella bacilliformis N E > cellular organisms N E > Bacteria N E > Proteobacteria N E > Alphaproteobacteria N E > Rhizobiales N E > Bartonellaceae N E > Bartonella N E > Bartonella bacilliformis N E > cellular organisms N E > Bacteria N E > Proteobacteria N E > Alphaproteobacteria N E > Rhizobiales N E > Bartonellaceae N E > Bartonella N E > Bartonella bacilliformis N E

Molecular evidence

No mutation

No structure

No kinetic

No disease

No substrate

Database

Sequence

Peptide

MVRFDGVTVK YITFLKYSVF FICIALLAAC GNKRAVLWHG INATPSMIAV QREVEGGPVL PKAIVPVYVA TSRKMQNNYS QPYGSERSNQ VYYNRVDVGI PQQHVKGKVE TNTYKPTHDK YFAAAALQKY IDKKHFKQKL NAELAKKKKG KREIFLFIHG YNNNFADGTF RAAQFAYDYS LDVVTVHYSW PSAGAIPLYV YDRDSANFAR DGLIELLTVI SETNADQISV IAHSMGNFVI MEAFRTLALQ RKYKPIRRIT SFLMAAPDID IDVFERQLND IKKLPNPTAV LVSRKDKALA VSGRLTGGHS RLGDGLSIEM LRKNGIAVLD VSNVDGGAHN VFASSPTLMT LSREGSLSST IMQGTEFSSS QAMLADSSNV LKETTNFTFY APIHLFSVVD FDP

References (3)

Title : Porin A and alpha\/beta-hydrolase are necessary and sufficient for hemolysis induced by Bartonella bacilliformis - Dichter_2025_Nat.Commun_16_10809
Author(s) : Dichter AA , Winklmeier F , Munteh D , Ballhorn W , Becker SA , Averhoff B , Bonig H , Goldman A , Garcia-Quintanilla M , Solis Cayo L , Tsukayama P , Kempf VAJ
Ref : Nat Commun , 16 :10809 , 2025
Abstract :
PubMedSearch : Dichter_2025_Nat.Commun_16_10809
PubMedID: 41315277
Gene_locus related to this paper: barbk-a1usj6

Title : Porin A and alpha\/beta-hydrolase are necessary and sufficient for hemolysis induced by Bartonella bacilliformis - Dichter_2025_Nat.Commun_16_10809
Author(s) : Dichter AA , Winklmeier F , Munteh D , Ballhorn W , Becker SA , Averhoff B , Bonig H , Goldman A , Garcia-Quintanilla M , Solis Cayo L , Tsukayama P , Kempf VAJ
Ref : Nat Commun , 16 :10809 , 2025
Abstract :
PubMedSearch : Dichter_2025_Nat.Commun_16_10809
PubMedID: 41315277
Gene_locus related to this paper: barbk-a1usj6

Title : Porin A and alpha\/beta-hydrolase are necessary and sufficient for hemolysis induced by Bartonella bacilliformis - Dichter_2025_Nat.Commun_16_10809
Author(s) : Dichter AA , Winklmeier F , Munteh D , Ballhorn W , Becker SA , Averhoff B , Bonig H , Goldman A , Garcia-Quintanilla M , Solis Cayo L , Tsukayama P , Kempf VAJ
Ref : Nat Commun , 16 :10809 , 2025
Abstract :
PubMedSearch : Dichter_2025_Nat.Commun_16_10809
PubMedID: 41315277
Gene_locus related to this paper: barbk-a1usj6