Coumarin-glycinate-Cpd9
AChE IC50 0.50 +/- 0.01 microM
General
Chemical_Nomenclature : 4-Methyl-2-oxo-2H-chromen-7-yl(2,5-dihydroxy-1H-pyrrole-1-carbonyl)glycinate
Canonical SMILES : [N]3(C(NCC(OC1=CC=C2C(=C1)OC(C=C2C)=O)=O)=O)C(=CC=C3O)O
InChI : InChI=1S\/C17H14N2O7\/c1-9-6-15(22)26-12-7-10(2-3-11(9)12)25-16(23)8-18-17(24)19-13(20)4-5-14(19)21\/h2-7,20-21H,8H2,1H3,(H,18,24)
InChIKey : DBUDHZCVUCTBTO-UHFFFAOYSA-N
Other name(s) : Compound 5h
Target
Families : Coumarin-glycinate-Cpd9 ligand of proteins in family
ACHE
Protein :
human-ACHE
References (1)
| Title : Neuroprotective potential of synthesized coumarin-based glycinate and heterocyclic amide derivatives: an acetylcholinesterase inhibition study - Farag_2026_Sci.Rep_16_26684 |
| Author(s) : Farag B , Shehab WS , Aly HF , Kiwan HS , Mousa SM , El-Bassyouni GT , Elsayed DA |
| Ref : Sci Rep , 16 :26684 , 2026 |
| Abstract : |
| PubMedSearch : Farag_2026_Sci.Rep_16_26684 |
| PubMedID: 42642505 |