Dichloro-phenylene-bis(phenyl-triazol)acetamide-Cpd4g
Ki nM hCA I 686.40 +/- 94.28; hCA II 239.10 +/- 31.48; AChE 125.90 +/- 13.49
General
Type : Multitarget, Triazol, Carbonic anhydrase inhibitor, Organochlorine
Chemical_Nomenclature : N,N'-(3,5-dichloro-1,2-phenylene)bis(2-(4-phenyl-1H-1,2,3-triazol-1-yl)acetamide)
Canonical SMILES : C1=C(C=C(C(=C1Cl)NC(=O)C[N]2N=NC(=C2)C3=CC=CC=C3)NC(=O)C[N]4C=C(N=N4)C5=CC=CC=C5)Cl
InChI : InChI=1S\/C26H20Cl2N8O2\/c27-19-11-20(28)26(30-25(38)16-36-14-23(32-34-36)18-9-5-2-6-10-18)21(12-19)29-24(37)15-35-13-22(31-33-35)17-7-3-1-4-8-17\/h1-14H,15-16H2,(H,29,37)(H,30,38)
InChIKey : YBNNYDPKBLGCKB-UHFFFAOYSA-N
Other name(s) : Compound 4g
acetamide-Cpd4g.gif)
Target
Families : Dichloro-phenylene-bis(phenyl-triazol)acetamide-Cpd4g ligand of proteins in family
ACHE
Protein :
human-ACHE
References (1)
| Title : New 1,2,3-triazole derivatives as acetylcholinesterase and carbonic anhydrase inhibitors: Synthesis, molecular docking, and solubility - Efeoglu_2025_Arch.Biochem.Biophys__110515 |
| Author(s) : Efeoglu C , Demir Y , Turkes C , Yabalak E , Seferoglu Z , Nural Y |
| Ref : Archives of Biochemistry & Biophysics , :110515 , 2025 |
| Abstract : |
| PubMedSearch : Efeoglu_2025_Arch.Biochem.Biophys__110515 |
| PubMedID: 40544906 |