Dicrotophos
Used to control sucking, boring, and chewing pests on rice, cotton, coffee, apples, and other crops. Effective on ornamentals, trees, and shrubs for aphids, leaf hoppers, and scale insects || . Dicrotophos: L. cuprina AChE, IC50 [nM] 2421 +/- 7 ; Human AChE, IC50 [nM] >30,000
General
Type : Organophosphate, Insecticide
Chemical_Nomenclature : [(E)-4-(dimethylamino)-4-oxobut-2-en-2-yl] dimethyl phosphate
Canonical SMILES : CC(=CC(=O)N(C)C)OP(=O)(OC)OC
InChI : InChI=1S\/C8H16NO5P\/c1-7(6-8(10)9(2)3)14-15(11,12-4)13-5\/h6H,1-5H3\/b7-6+
InChIKey : VEENJGZXVHKXNB-VOTSOKGWSA-N
Other name(s) : (E)-Phosphoric acid 3-(dimethylamino)-1-methyl-3-oxo-1-prophenyl dimethyl ester || (E)-3-(dimethylamino)-1-methyl-3-oxo-1-propenyl dimethyl phosphate || bidrin carbicron ektafos || Bidrin || Carbicron || Diapadrin || Ektafos || Carbomicron || Oleobidrin || Karbicron || CHEBI:38658 || RefChem:133185 || SCHEMBL26457 || CHEMBL1876467
MW : 237.21
Formula : C8H16NO5P
CAS_number : 141-66-2
PubChem : 5371560
UniChem : VEENJGZXVHKXNB-VOTSOKGWSA-N
Wikipedia : Dicrotophos
Target
Families : Dicrotophos ligand of proteins in family
ACHE
References (4)
| Title : The characterization of Lucilia cuprina acetylcholinesterase as a drug target, and the identification of novel inhibitors by high throughput screening - Ilg_2011_Insect.Biochem.Mol.Biol_41_470 |
| Author(s) : Ilg T , Cramer J , Lutz J , Noack S , Schmitt H , Williams H , Newton T |
| Ref : Insect Biochemistry & Molecular Biology , 41 :470 , 2011 |
| Abstract : |
| PubMedSearch : Ilg_2011_Insect.Biochem.Mol.Biol_41_470 |
| PubMedID: 21530657 |
| Title : Recovery of brain and plasma cholinesterase activities in ducklings exposed to organophosphorus pesticides - Fleming_1981_Arch.Environ.Contam.Toxicol_10_215 |
| Author(s) : Fleming WJ |
| Ref : Archives of Environmental Contamination & Toxicology , 10 :215 , 1981 |
| Abstract : |
| PubMedSearch : Fleming_1981_Arch.Environ.Contam.Toxicol_10_215 |
| PubMedID: 7224673 |
| Title : Ixodicidal resistance in Boophilus microplus (Canestrini) in the Republic of South Africa and Transkei - Baker_1979_J.S.Afr.Vet.Assoc_50_296 |
| Author(s) : Baker JA , Jordaan JO , Robertson WD |
| Ref : J S Afr Vet Assoc , 50 :296 , 1979 |
| Abstract : |
| PubMedSearch : Baker_1979_J.S.Afr.Vet.Assoc_50_296 |
| PubMedID: 553968 |
| Title : Evaluation of cytotoxic responses caused by selected organophosphorus esters in chick sympathetic ganglia cultures - Obersteiner_1978_Can.J.Comp.Med_42_80 |
| Author(s) : Obersteiner EJ , Sharma RP |
| Ref : Can J Comp Med , 42 :80 , 1978 |
| Abstract : |
| PubMedSearch : Obersteiner_1978_Can.J.Comp.Med_42_80 |
| PubMedID: 565668 |