EMPC

"fluorescent leaving group is 7HMC (7-Hydroxy-4-methylcoumarin)" || "Close to coumaphos"

General

Type : Organophosphate,Coumarin

Chemical_Nomenclature : 7-[ethoxy(methyl)phosphoryl]oxy-4-methylchromen-2-one

Canonical SMILES : CCOP(=O)(C)OC1=CC2=C(C=C1)C(=CC(=O)O2)C

InChI : InChI=1S\/C13H15O5P\/c1-4-16-19(3,15)18-10-5-6-11-9(2)7-13(14)17-12(11)8-10\/h5-8H,4H2,1-3H3

InChIKey : IRTYKYONNHLPIW-UHFFFAOYSA-N

Other name(s) : 4-Methyl-7-(methylethoxyphosphinyloxy)coumarin,7-[(methylethoxyphosphonyl)oxy]-4-methylcoumarin


MW : 282.22

Formula : C13H15O5P

CAS_number :

PubChem : 16095834

UniChem : IRTYKYONNHLPIW-UHFFFAOYSA-N

IUPHAR :

Wikipedia :

Target

Families : EMPC ligand of proteins in family: ACHE

Stucture :

Protein :

References (1)

Title : A steric blockade model for inhibition of acetylcholinesterase by peripheral site ligands and substrate - Rosenberry_1999_Chem.Biol.Interact_119-120_85
Author(s) : Rosenberry TL , Mallender WD , Thomas PJ , Szegletes T
Ref : Chemico-Biological Interactions , 119-120 :85 , 1999
Abstract : Rosenberry_1999_Chem.Biol.Interact_119-120_85
ESTHER : Rosenberry_1999_Chem.Biol.Interact_119-120_85
PubMedSearch : Rosenberry_1999_Chem.Biol.Interact_119-120_85
PubMedID: 10421442