Hydroxygenkwanin
IC50 Porcine pancreatic lipase microM0.128 +/- 0.009 Competitive
General
Chemical_Nomenclature : 2-(3,4-dihydroxyphenyl)-5-hydroxy-7-methoxychromen-4-one
Canonical SMILES : COC1=CC(=C2C(=C1)OC(=CC2=O)C3=CC(=C(C=C3)O)O)O
InChI : InChI=1S\/C16H12O6\/c1-21-9-5-12(19)16-13(20)7-14(22-15(16)6-9)8-2-3-10(17)11(18)4-8\/h2-7,17-19H,1H3
InChIKey : RRRSSAVLTCVNIQ-UHFFFAOYSA-N
Other name(s) : HYD || 7-O-Methylluteolin || Luteolin 7-methyl ether || 4H-1-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-5-hydroxy-7-methoxy- || RefChem:925005 || CHEMBL183745 || SCHEMBL4203893 || SCHEMBL30074462 || CHEBI:168675
MW : 300.26
Formula : C16H12O6
CAS_number : 20243-59-8
PubChem : 5318214
UniChem : RRRSSAVLTCVNIQ-UHFFFAOYSA-N
Target
Families : Hydroxygenkwanin ligand of proteins in family
Pancreatic_lipase
Protein :
human-PNLIP
References (1)
| Title : Identification of Potential Pancreatic Lipase Inhibitors from Traditional Chinese Medicines via Molecular Docking, Molecular Dynamics Simulation and In Vitro Validation - Zhang_2026_Curr.Issues.Mol.Biol_48_404 |
| Author(s) : Zhang Z , Long J , Li T , Xu N , Xu Z , Wang Y , Chu M , Zhang M |
| Ref : Curr Issues Mol Biol , 48 :404 , 2026 |
| Abstract : |
| PubMedSearch : Zhang_2026_Curr.Issues.Mol.Biol_48_404 |
| PubMedID: 42042064 |