ILAPPER

Hydrolysate from oyster (Crassostrea gigas) IC50 16.98 micromol/L

General

Type : Natural, Peptide

Chemical_Nomenclature : ILAPPER || ILE-LEU-ALA-PRO-PRO-GLU-ARG

Canonical SMILES : NC(C(NC(C(NC(C(N1C(CCC1)C(=O)N2CCCC2C(=O)NC(CCC(=O)O)C(=O)NC(C(=O)O)CCCNC(N)N)=O)C)=O)CC(C)C)=O)C(CC)C

InChI : InChI=1S\/C36H64N10O10\/c1-6-20(4)28(37)32(52)44-24(18-19(2)3)30(50)41-21(5)33(53)46-17-9-12-26(46)34(54)45-16-8-11-25(45)31(51)42-22(13-14-27(47)48)29(49)43-23(35(55)56)10-7-15-40-36(38)39\/h19-26,28,36,40H,6-18,37-39H2,1-5H3,(H,41,50)(H,42,51)(H,43,49)(H,44,52)(H,47,48)(H,55,56)

InChIKey : KDUOZRQJUCRGFW-UHFFFAOYSA-N

Other name(s) : ILE-LEU-ALA-PRO-PRO-GLU-ARG


MW : 796.963

Formula : C36H64N10O10

CAS_number :

PubChem :

UniChem : KDUOZRQJUCRGFW-UHFFFAOYSA-N

Target

Families : ILAPPER ligand of proteins in family
DPP4N_Peptidase_S9

Structure :
7XNM

Protein :
pig-dpp4

References (2)

Title : Purification, crystal structural characterization of porcine kidney dipeptidyl peptidase IV (PkDPP-IV) and its interaction with oyster derived inhibitory peptide ILAPPER - Li_2025_Int.J.Biol.Macromol__140047
Author(s) : Li WY , Chen H , Lin D , Zhang T , Chen YL , Jin T , Cao MJ
Ref : Int J Biol Macromol , :140047 , 2025
Abstract :
PubMedSearch : Li_2025_Int.J.Biol.Macromol__140047
PubMedID: 39828169
Gene_locus related to this paper: pig-dpp4

Title : Preparation and activity analysis of DPP-IV inhibitory peptides from Pacific oyster (Crassostrea gigas) - Chen_2021_Food.Sci_42_120
Author(s) : Chen H , Zhang Q , Chen YL , Weng L , Zhang LJ , Xie SH , Liu GM , Cao MJ
Ref : Food Science , 42 :120 , 2021
Abstract :
PubMedSearch : Chen_2021_Food.Sci_42_120
PubMedID: