JJ-OX-009
JJ-0X-009 IC50 FphB 30 +/- 7 microM FphE 0.3 +/- 0.1 microM
General
Type : Oxadiazolone, Oxadiazol
Chemical_Nomenclature :
Canonical SMILES : NOCC(NC1=CC=C(C=C1)N2C(OC(=N2)OC)=O)=O
InChI : InChI=1S\/C11H12N4O5\/c1-18-10-14-15(11(17)20-10)8-4-2-7(3-5-8)13-9(16)6-19-12\/h2-5H,6,12H2,1H3,(H,13,16)
InChIKey : LPHXTLBMIOEINV-UHFFFAOYSA-N
Other name(s) : JJ009
Target
Families : JJ-OX-009 ligand of proteins in family
6_AlphaBeta_hydrolase
Protein :
staau-SA2367
References (1)
| Title : An mRNA Display Approach for Covalent Targeting of a Staphylococcus aureus Virulence Factor - Wang_2025_J.Am.Chem.Soc__ |
| Author(s) : Wang S , Woods EC , Jo J , Zhu J , Hansel-Harris A , Holcomb M , Llanos M , Pedowitz NJ , Upadhyay T , Bennett J , Fellner M , Park KW , Zhang A , Valdez TA , Forli S , Chan AI , Cunningham CN , Bogyo M |
| Ref : Journal of the American Chemical Society , : , 2025 |
| Abstract : |
| PubMedSearch : Wang_2025_J.Am.Chem.Soc__ |
| PubMedID: 40013487 |
| Gene_locus related to this paper: staau-MW2456 , staau-SA2367 |