Methylene-Violet-3RAX
3-Amino-7-diethylamino-5-phenylphenazin-5-ium is the parent compound CID 2733868 || hyperbolic noncompetitive inhibitor of AChE with Ki value of 1.58+/-0.36muM; alpha=1; beta=0.12+/-0.0003. Caused linear competitive inhibition of BChE with Ki value of 0.51+/-0.006muM
General
Chemical_Nomenclature : 2-N,2-N-diethyl-10-phenylphenazin-10-ium-2,8-diamine\;chloride
Canonical SMILES : CCN(CC)C1=CC2=[N+](C3=C(C=CC(=C3)N)N=C2C=C1)C4=CC=CC=C4.[Cl-]
InChI : InChI=1S\/C22H22N4.ClH\/c1-3-25(4-2)18-11-13-20-22(15-18)26(17-8-6-5-7-9-17)21-14-16(23)10-12-19(21)24-20\;\/h5-15,23H,3-4H2,1-2H3\;1H
InChIKey : MOVNSGGBTSIUGX-UHFFFAOYSA-N
Other name(s) : Methylene Violet 3RAX || 3-amino-7-(diethylamino)-5-phenylphenazin-5-ium chloride || N,N-Diethylphenosafranine || MFCD00013433 || Diethyl safranine || Diethylsafranine || SCHEMBL930666 || CHEMBL1457403 || SCHEMBL3130463 || CHEMBL1621499 || SCHEMBL20329168
MW : 378.9
Formula : C22H23ClN4
CAS_number : 4569-86-2
PubChem :
UniChem : MOVNSGGBTSIUGX-UHFFFAOYSA-N
References (1)
| Title : The kinetics of inhibition of human acetylcholinesterase and butyrylcholinesterase by methylene violet 3RAX - Onder_2019_Chem.Biol.Interact_314_108845 |
| Author(s) : Onder S , Biberoglu K , Tacal O |
| Ref : Chemico-Biological Interactions , 314 :108845 , 2019 |
| Abstract : |
| PubMedSearch : Onder_2019_Chem.Biol.Interact_314_108845 |
| PubMedID: 31593690 |