Methylene-Violet-3RAX

3-Amino-7-diethylamino-5-phenylphenazin-5-ium is the parent compound CID 2733868 || hyperbolic noncompetitive inhibitor of AChE with Ki value of 1.58+/-0.36muM; alpha=1; beta=0.12+/-0.0003. Caused linear competitive inhibition of BChE with Ki value of 0.51+/-0.006muM

General

Type : Phenazine, Dye

Chemical_Nomenclature : 2-N,2-N-diethyl-10-phenylphenazin-10-ium-2,8-diamine\;chloride

Canonical SMILES : CCN(CC)C1=CC2=[N+](C3=C(C=CC(=C3)N)N=C2C=C1)C4=CC=CC=C4.[Cl-]

InChI : InChI=1S\/C22H22N4.ClH\/c1-3-25(4-2)18-11-13-20-22(15-18)26(17-8-6-5-7-9-17)21-14-16(23)10-12-19(21)24-20\;\/h5-15,23H,3-4H2,1-2H3\;1H

InChIKey : MOVNSGGBTSIUGX-UHFFFAOYSA-N

Other name(s) : Methylene Violet 3RAX, 3-amino-7-(diethylamino)-5-phenylphenazin-5-ium chloride, N,N-Diethylphenosafranine, MFCD00013433, Diethyl safranine, Diethylsafranine, SCHEMBL930666, CHEMBL1457403, SCHEMBL3130463, CHEMBL1621499, SCHEMBL20329168


MW : 378.9

Formula : C22H23ClN4

CAS_number : 4569-86-2

PubChem :

UniChem : MOVNSGGBTSIUGX-UHFFFAOYSA-N

Target

Families : Methylene-Violet-3RAX ligand of proteins in family
ACHE BCHE

References (1)

Title : The kinetics of inhibition of human acetylcholinesterase and butyrylcholinesterase by methylene violet 3RAX - Onder_2019_Chem.Biol.Interact_314_108845
Author(s) : Onder S , Biberoglu K , Tacal O
Ref : Chemico-Biological Interactions , 314 :108845 , 2019
PubMedID: 31593690