Omethoate
oxon du dimethoate || Substrate of strmu-SMU.1393C a scavenger of OP || . Omethoate: L. cuprina AChE, IC50 [nM] 1156 +/- 171 ; Human AChE, IC50 [nM] >30,000
General
Type : Organophosphate, Sulfur Compound, Insecticide
Chemical_Nomenclature : O,O-dimethyl S-(2-methylamino)-2-oxoethyl phosphorothioate\;
Canonical SMILES : CNC(=O)CSP(=O)(OC)OC
InChI : InChI=1S\/C5H12NO4PS\/c1-6-5(7)4-12-11(8,9-2)10-3\/h4H2,1-3H3,(H,6,7)
InChIKey : PZXOQEXFMJCDPG-UHFFFAOYSA-N
Other name(s) : dimethoate oxygen analog || dimethoxon || Dimethoate oxon || Folimat || BAY 45432 || RefChem:168221 || SCHEMBL63063 || CHEMBL2270068
MW : 213.19
Formula : C5H12NO4PS
CAS_number : 1113-02-6
PubChem : 14210
UniChem : PZXOQEXFMJCDPG-UHFFFAOYSA-N
Wikipedia : Omethoate
Target
Families : Omethoate ligand of proteins in family
ACHE
BCHE
6_AlphaBeta_hydrolase
Protein :
strmu-SMU.1393C
References (4)
| Title : Harnessing Nature's Diversity: Discovering organophosphate bioscavenger characteristics among low molecular weight proteins - Jacob_2016_Sci.Rep_6_37175 |
| Author(s) : Jacob RB , Michaels KC , Anderson CJ , Fay JM , Dokholyan NV |
| Ref : Sci Rep , 6 :37175 , 2016 |
| Abstract : |
| PubMedSearch : Jacob_2016_Sci.Rep_6_37175 |
| PubMedID: 27845442 |
| Gene_locus related to this paper: strmu-SMU.1393C |
| Title : The characterization of Lucilia cuprina acetylcholinesterase as a drug target, and the identification of novel inhibitors by high throughput screening - Ilg_2011_Insect.Biochem.Mol.Biol_41_470 |
| Author(s) : Ilg T , Cramer J , Lutz J , Noack S , Schmitt H , Williams H , Newton T |
| Ref : Insect Biochemistry & Molecular Biology , 41 :470 , 2011 |
| Abstract : |
| PubMedSearch : Ilg_2011_Insect.Biochem.Mol.Biol_41_470 |
| PubMedID: 21530657 |
| Title : Intermediate myasthenia syndrome following acute organophosphates poisoning--an analysis of 21 cases - He_1998_Hum.Exp.Toxicol_17_40 |
| Author(s) : He F , Xu H , Qin F , Xu L , Huang J , He X |
| Ref : Hum Exp Toxicol , 17 :40 , 1998 |
| Abstract : |
| PubMedSearch : He_1998_Hum.Exp.Toxicol_17_40 |
| PubMedID: 9491337 |
| Title : Selective, solid-matrix dispersion extraction of organophosphate pesticide residues from milk - Di Muccio_1996_J.Chromatogr.A_754_497 |
| Author(s) : Di Muccio A , Pelosi P , Camoni I , Attard Barbini D , Dommarco R , Generali T , Ausili A |
| Ref : Journal of Chromatography A , 754 :497 , 1996 |
| Abstract : |
| PubMedSearch : Di Muccio_1996_J.Chromatogr.A_754_497 |
| PubMedID: 8997741 |