Petroselenic-acid
Petroselinic acid is a natural f octadec-6-enoic acid, a long-chain fatty acid found in Agaricus blazei, Angelica ternata. Recently, PSA was shown to inhibit S. aureus biofilm formation and the enzymatic activity of Staphylococcus aureus lipase and biofilm formation
General
Type : Fatty acid, Natural
Chemical_Nomenclature : (Z)-octadec-6-enoic acid
Canonical SMILES : CCCCCCCCCCCC=CCCCCC(=O)O
InChI : InChI=1S\/C18H34O2\/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20\/h12-13H,2-11,14-17H2,1H3,(H,19,20)\/b13-12-
InChIKey : CNVZJPUDSLNTQU-SEYXRHQNSA-N
Other name(s) : (Z)-Octadec-6-enoic acid || cis-6-Octadecenoic acid || Petroselenic acid || Petroselic acid || PSA || CHEBI:28194 || SCHEMBL93332 || C18:1n-12 || 18:1(N-12) || CHEMBL3139878 || 4I1
MW : 282.5
Formula : C18H34O2
CAS_number : 593-39-5
PubChem : 5281125
UniChem : CNVZJPUDSLNTQU-SEYXRHQNSA-N
Target
Families : Petroselenic-acid ligand of proteins in family
Bacterial_lip_FamI.6
Protein :
staau-lipas
References (6)
| Title : Crystal structure of Staphylococcus aureus lipase complex with unsaturated petroselinic acid - Kitadokoro_2024_FEBS.Open.Bio__ |
| Author(s) : Kitadokoro J , Kamitani S , Okuno Y , Hikima T , Yamamoto M , Hirokawa T , Kitadokoro K |
| Ref : FEBS Open Bio , : , 2024 |
| Abstract : |
| PubMedSearch : Kitadokoro_2024_FEBS.Open.Bio__ |
| PubMedID: 38757397 |
| Title : Inhibition of Staphylococcus aureus Biofilm Formation and Virulence Factor Production by Petroselinic Acid and Other Unsaturated C18 Fatty Acids - Lee_2022_Microbiol.Spectr_10_e0133022 |
| Author(s) : Lee JH , Kim YG , Lee J |
| Ref : Microbiol Spectr , 10 :e0133022 , 2022 |
| Abstract : |
| PubMedSearch : Lee_2022_Microbiol.Spectr_10_e0133022 |
| PubMedID: 35647620 |
| Title : A plasma fatty acid profile associated to type 2 diabetes development: from the CORDIOPREV study - Villasanta-Gonzalez_2022_Eur.J.Nutr_61_843 |
| Author(s) : Villasanta-Gonzalez A , Alcala-Diaz JF , Vals-Delgado C , Arenas AP , Cardelo MP , Romero-Cabrera JL , Rodriguez-Cantalejo F , Delgado-Lista J , Malagon MM , Perez-Martinez P , Schulze MB , Camargo A , Lopez-Miranda J |
| Ref : Eur J Nutr , 61 :843 , 2022 |
| Abstract : |
| PubMedSearch : Villasanta-Gonzalez_2022_Eur.J.Nutr_61_843 |
| PubMedID: 34609622 |
| Title : Petroselinic acid from dietary triacylglycerols reduces the concentration of arachidonic acid in tissue lipids of rats - Weber_1995_J.Nutr_125_1563 |
| Author(s) : Weber N , Richter KD , Schulte E , Mukherjee KD |
| Ref : J Nutr , 125 :1563 , 1995 |
| Abstract : |
| PubMedSearch : Weber_1995_J.Nutr_125_1563 |
| PubMedID: 7782911 |
| Title : Specificities of the Acyl-Acyl Carrier Protein (ACP) Thioesterase and Glycerol-3-Phosphate Acyltransferase for Octadecenoyl-ACP Isomers (Identification of a Petroselinoyl-ACP Thioesterase in Umbelliferae) - Dormann_1994_Plant.Physiol_104_839 |
| Author(s) : Dormann P , Frentzen M , Ohlrogge JB |
| Ref : Plant Physiol , 104 :839 , 1994 |
| Abstract : |
| PubMedSearch : Dormann_1994_Plant.Physiol_104_839 |
| PubMedID: 12232130 |
| Title : Studies on the specificity of a lipase system fromGeotrichum candidum - Marks_1968_Lipids_3_143 |
| Author(s) : Marks TA , Quinn JG , Sampugna J , Jensen RG |
| Ref : Lipids , 3 :143 , 1968 |
| Abstract : |
| PubMedSearch : Marks_1968_Lipids_3_143 |
| PubMedID: 17805902 |