Pregnenolone-carbamate-derivative-CpdP3
eleel AChE 0.11 +/- 0.04 microM
General
Type : Natural_modified, Carbamate, Steroid, Phenanthrene
Chemical_Nomenclature : Diethyl (1S,2R,5S,10S,11S,14S,15S)-14-acetyl-2,15-dimethyltetracyclo[8.7.0.02,7.011,15]heptadec-7-ene-5-carbamate
Canonical SMILES : CCN(CC)C(=O)O[C@H]4CC[C@@]2(C)C(=CC[C@H]3[C@@H]1CC[C@H](C(C)=O)[C@@]1(C)CC[C@H]23)C4
InChI : InChI=1S\/C26H41NO3\/c1-6-27(7-2)24(29)30-19-12-14-25(4)18(16-19)8-9-20-22-11-10-21(17(3)28)26(22,5)15-13-23(20)25\/h8,19-23H,6-7,9-16H2,1-5H3\/t19-,20-,21+,22-,23-,25-,26+\/m0\/s1
InChIKey : IXRUHOUCIMTHMX-QSZUEJIDSA-N
Other name(s) : Compound P3
Target
Families : Pregnenolone-carbamate-derivative-CpdP3 ligand of proteins in family
ACHE
Protein :
human-ACHE
References (1)
| Title : Pregnenolone Carbamate Derivatives as Selective Cholinesterase Inhibitors: Multimodal Evaluation Including DNA and HSA Interactions - Akca_2025_Arch.Pharm.(Weinheim)_358_e70140 |
| Author(s) : Akca S , Ilkar Erdagi S , Ozbagci DI |
| Ref : Arch Pharm (Weinheim) , 358 :e70140 , 2025 |
| Abstract : |
| PubMedSearch : Akca_2025_Arch.Pharm.(Weinheim)_358_e70140 |
| PubMedID: 41189504 |