SUAM-14746
General
Type : Thiazolidine, Sulfur Compound
Chemical_Nomenclature : 1-[(2~{S})-4-hydroxy-2-(1,3-thiazolidine-3-carbonyl)pyrrolidin-1-yl]-4-[2-[(~{E})-2-phenylethenyl]phenoxy]butan-1-one
Canonical SMILES : C1CSCN1C(=O)C2CC(CN2C(=O)CCCOC3=CC=CC=C3C=CC4=CC=CC=C4)O
InChI : InChI=1S\/C26H30N2O4S\/c29-22-17-23(26(31)27-14-16-33-19-27)28(18-22)25(30)11-6-15-32-24-10-5-4-9-21(24)13-12-20-7-2-1-3-8-20\/h1-5,7-10,12-13,22-23,29H,6,11,14-19H2\/b13-12+\/t22?,23-\/m0\/s1
InChIKey : VJHGOPMDXSBFHZ-DDYZFRKMSA-N
Other name(s) : BKO || SCHEMBL20484097 || 3-({4-[2-(e)-styrylphenoxy]butanoyl}-l-4-hydroxyprolyl)-thiazolidine
MW : 466.59
Formula : C26H30N2O4S
CAS_number :
PubChem : 102296095
UniChem : VJHGOPMDXSBFHZ-DDYZFRKMSA-N
Target
Families : SUAM-14746 ligand of proteins in family
S9N_PPCE_Peptidase_S9
Structure :
6JCI
Protein :
haldh-a0a1x9t5x9
human-PREP
References (12)
| Title : The prolyl oligopeptidase inhibitor SUAM-14746 attenuates the proliferation of human breast cancer cell lines in vitro - Tanaka_2017_Breast.Cancer_24_658 |
| Author(s) : Tanaka S , Suzuki K , Sakaguchi M |
| Ref : Breast Cancer , 24 :658 , 2017 |
| Abstract : |
| PubMedSearch : Tanaka_2017_Breast.Cancer_24_658 |
| PubMedID: 28070831 |
| Title : Mouse prolyl oligopeptidase plays a role in trophoblast stem cell differentiation into trophoblast giant cell and spongiotrophoblast - Maruyama_2017_Placenta_53_8 |
| Author(s) : Maruyama Y , Matsubara S , Kimura AP |
| Ref : Placenta , 53 :8 , 2017 |
| Abstract : |
| PubMedSearch : Maruyama_2017_Placenta_53_8 |
| PubMedID: 28487025 |
| Title : The prolyl oligopeptidase inhibitor SUAM-14746 attenuates the proliferation of human breast cancer cell lines in vitro - Tanaka_2017_Breast.Cancer_24_658 |
| Author(s) : Tanaka S , Suzuki K , Sakaguchi M |
| Ref : Breast Cancer , 24 :658 , 2017 |
| Abstract : |
| PubMedSearch : Tanaka_2017_Breast.Cancer_24_658 |
| PubMedID: 28070831 |
| Title : Mouse prolyl oligopeptidase plays a role in trophoblast stem cell differentiation into trophoblast giant cell and spongiotrophoblast - Maruyama_2017_Placenta_53_8 |
| Author(s) : Maruyama Y , Matsubara S , Kimura AP |
| Ref : Placenta , 53 :8 , 2017 |
| Abstract : |
| PubMedSearch : Maruyama_2017_Placenta_53_8 |
| PubMedID: 28487025 |
| Title : The prolyl oligopeptidase inhibitor SUAM-14746 attenuates the proliferation of human breast cancer cell lines in vitro - Tanaka_2017_Breast.Cancer_24_658 |
| Author(s) : Tanaka S , Suzuki K , Sakaguchi M |
| Ref : Breast Cancer , 24 :658 , 2017 |
| Abstract : |
| PubMedSearch : Tanaka_2017_Breast.Cancer_24_658 |
| PubMedID: 28070831 |
| Title : Mouse prolyl oligopeptidase plays a role in trophoblast stem cell differentiation into trophoblast giant cell and spongiotrophoblast - Maruyama_2017_Placenta_53_8 |
| Author(s) : Maruyama Y , Matsubara S , Kimura AP |
| Ref : Placenta , 53 :8 , 2017 |
| Abstract : |
| PubMedSearch : Maruyama_2017_Placenta_53_8 |
| PubMedID: 28487025 |
| Title : Prolyl oligopeptidase inhibition-induced growth arrest of human gastric cancer cells - Suzuki_2014_Biochem.Biophys.Res.Commun_443_91 |
| Author(s) : Suzuki K , Sakaguchi M , Tanaka S , Yoshimoto T , Takaoka M |
| Ref : Biochemical & Biophysical Research Communications , 443 :91 , 2014 |
| Abstract : |
| PubMedSearch : Suzuki_2014_Biochem.Biophys.Res.Commun_443_91 |
| PubMedID: 24269815 |
| Gene_locus related to this paper: human-PREP |
| Title : Prolyl oligopeptidase inhibition-induced growth arrest of human gastric cancer cells - Suzuki_2014_Biochem.Biophys.Res.Commun_443_91 |
| Author(s) : Suzuki K , Sakaguchi M , Tanaka S , Yoshimoto T , Takaoka M |
| Ref : Biochemical & Biophysical Research Communications , 443 :91 , 2014 |
| Abstract : |
| PubMedSearch : Suzuki_2014_Biochem.Biophys.Res.Commun_443_91 |
| PubMedID: 24269815 |
| Gene_locus related to this paper: human-PREP |
| Title : Prolyl oligopeptidase inhibition-induced growth arrest of human gastric cancer cells - Suzuki_2014_Biochem.Biophys.Res.Commun_443_91 |
| Author(s) : Suzuki K , Sakaguchi M , Tanaka S , Yoshimoto T , Takaoka M |
| Ref : Biochemical & Biophysical Research Communications , 443 :91 , 2014 |
| Abstract : |
| PubMedSearch : Suzuki_2014_Biochem.Biophys.Res.Commun_443_91 |
| PubMedID: 24269815 |
| Gene_locus related to this paper: human-PREP |
| Title : Prolyl oligopeptidase participates in cell cycle progression in a human neuroblastoma cell line - Sakaguchi_2011_Biochem.Biophys.Res.Commun_409_693 |
| Author(s) : Sakaguchi M , Matsuda T , Matsumura E , Yoshimoto T , Takaoka M |
| Ref : Biochemical & Biophysical Research Communications , 409 :693 , 2011 |
| Abstract : |
| PubMedSearch : Sakaguchi_2011_Biochem.Biophys.Res.Commun_409_693 |
| PubMedID: 21620802 |
| Title : Prolyl oligopeptidase participates in cell cycle progression in a human neuroblastoma cell line - Sakaguchi_2011_Biochem.Biophys.Res.Commun_409_693 |
| Author(s) : Sakaguchi M , Matsuda T , Matsumura E , Yoshimoto T , Takaoka M |
| Ref : Biochemical & Biophysical Research Communications , 409 :693 , 2011 |
| Abstract : |
| PubMedSearch : Sakaguchi_2011_Biochem.Biophys.Res.Commun_409_693 |
| PubMedID: 21620802 |
| Title : Prolyl oligopeptidase participates in cell cycle progression in a human neuroblastoma cell line - Sakaguchi_2011_Biochem.Biophys.Res.Commun_409_693 |
| Author(s) : Sakaguchi M , Matsuda T , Matsumura E , Yoshimoto T , Takaoka M |
| Ref : Biochemical & Biophysical Research Communications , 409 :693 , 2011 |
| Abstract : |
| PubMedSearch : Sakaguchi_2011_Biochem.Biophys.Res.Commun_409_693 |
| PubMedID: 21620802 |