Thiazolidinedione-7r
IC50 2.67 +/- 0.32 microM
General
Type : Sulfur Compound, Thiazolidine, Thiazolinone
Chemical_Nomenclature : (Z)-5-({1-[(1E,5E)-1,5-Dimethyl-1,5-heptadienyl]-3-indolyl}methylene)-3-[2-(3-indolyl)ethyl]-1,3-thiazolidine-2,4-dione
Canonical SMILES : C1(=C[N]C2=C1C=CC=C2)CCN3C(C(SC3=O)=CC4=C[N](C5=C4C=CC=C5)C(=CCCC(=CC)C)C)=O
InChI : InChI=1S\/C31H31N3O2S\/c1-4-21(2)10-9-11-22(3)34-20-24(26-13-6-8-15-28(26)34)18-29-30(35)33(31(36)37-29)17-16-23-19-32-27-14-7-5-12-25(23)27\/h4-8,11-15,18-20,32H,9-10,16-17H2,1-3H3
InChIKey : IAJGGELMHIHAAC-UHFFFAOYSA-N
Other name(s) : Compound 7r || Compound 44r
Target
Families : Thiazolidinedione-7r ligand of proteins in family
Pancreatic_lipase
Protein :
human-PNLIP
References (1)
| Title : Synthesis, molecular modelling and pharmacological evaluation of novel indole-thiazolidinedione based hybrid analogues as potential pancreatic lipase inhibitors - George_2023_J.Biomol.Struct.Dyn__1 |
| Author(s) : George G , Auti PS , Sengupta P , Yadav N , Paul AT |
| Ref : J Biomol Struct Dyn , :1 , 2023 |
| Abstract : |
| PubMedSearch : George_2023_J.Biomol.Struct.Dyn__1 |
| PubMedID: 38095559 |
| Gene_locus related to this paper: human-PNLIP |