Zectran
. Mexacarbate : L. cuprina AChE, IC50 [nM] 131 +/- 27 ; Human AChE, IC50 [nM] 6111 +/- 534
General
Type : Carbamate, Insecticide
Chemical_Nomenclature : 4-Dimethylamino-3,5-Dimethylphenol Methylcarbamate Ester
Canonical SMILES : CC1=CC(=CC(=C1N(C)C)C)OC(=O)NC
InChI : InChI=1S\/C12H18N2O2\/c1-8-6-10(16-12(15)13-3)7-9(2)11(8)14(4)5\/h6-7H,1-5H3,(H,13,15)
InChIKey : YNEVBPNZHBAYOA-UHFFFAOYSA-N
Other name(s) : 4-(dimethylamino)-3,5-dimethylphenol, methylcarbamate || Zactran || mexacarbate || Zectane || Mexacarbamate || Mexacarbole
MW : 222.29
Formula : C12H18N2O2
CAS_number : 315-18-4
PubChem : 9414
UniChem : YNEVBPNZHBAYOA-UHFFFAOYSA-N
Wikipedia : Mexacarbate
Target
Families : Zectran ligand of proteins in family
ACHE
References (2)
| Title : The characterization of Lucilia cuprina acetylcholinesterase as a drug target, and the identification of novel inhibitors by high throughput screening - Ilg_2011_Insect.Biochem.Mol.Biol_41_470 |
| Author(s) : Ilg T , Cramer J , Lutz J , Noack S , Schmitt H , Williams H , Newton T |
| Ref : Insect Biochemistry & Molecular Biology , 41 :470 , 2011 |
| Abstract : |
| PubMedSearch : Ilg_2011_Insect.Biochem.Mol.Biol_41_470 |
| PubMedID: 21530657 |
| Title : Inhibition kinetics of certain organophosphorus and carbamate pesticides on acetylcholinesterase from the snail Lymnaea acuminata - Singh_1983_Toxicol.Lett_19_313 |
| Author(s) : Singh DK , Agarwal RA |
| Ref : Toxicol Lett , 19 :313 , 1983 |
| Abstract : |
| PubMedSearch : Singh_1983_Toxicol.Lett_19_313 |
| PubMedID: 6658844 |