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Nu-1250

General

Type : Carbamate,Trimethylammonium

Chemical_Nomenclature : N-p-chlorophenyl-N-methylcarbamate of m-hydroxyphenyltrimethylammonium bromide

Canonical SMILES : C1=C(C=CC=C1OC(N(C)C2=CC=C(C=C2)Cl)=O)[N+](C)(C)C.[Br-]

InChI : InChI=1S\/C17H20ClN2O2.BrH\/c1-19(14-10-8-13(18)9-11-14)17(21)22-16-7-5-6-15(12-16)20(2,3)4\;\/h5-12H,1-4H3\;1H\/q+1\;\/p-1

InChIKey : PCQGALCVXJWHNH-UHFFFAOYSA-M

Other name(s) :

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MW : 399,71

Formula : C17H20N2O2ClBr

CAS_number :

PubChem :

UniChem : PCQGALCVXJWHNH-UHFFFAOYSA-M

Target

Families : Nu-1250 ligand of proteins in family
ACHE

References (3)

1. Anticholinesterases in the heart-lung preparation

Title : Anticholinesterases in the heart-lung preparation -

Author(s) : Burn JH , Walker JM

Ref : Journal de Physiologie , 124 :489 , 1954

PubMedID: 13175193

2. [Anticholinesteratic and pharmacological effects of the bromide of N-P-Chlorophenyl-methylcarbamate of M-Hydroxyphenyltrimethylammonium (NU 1250)]

Title : [Anticholinesteratic and pharmacological effects of the bromide of N-P-Chlorophenyl-methylcarbamate of M-Hydroxyphenyltrimethylammonium (NU 1250)] -

Author(s) : Casier H , De Vleeschhouwer GR

Ref : Archives Internationales de Pharmacodynamie et de Therapie , 90 :412 , 1952

PubMedID: 12986938

3. Tubocurarine antagonism and inhibition of cholinesterases

Title : Tubocurarine antagonism and inhibition of cholinesterases -

Author(s) : Blaschko H , Bulbring E , Chou TC

Ref : British Journal of Pharmacology , 4 :29 , 1949

PubMedID: 18113150

Array
(
    [id] => 4995
    [inhibitor] => Nu-1250
    [type] => Array
        (
            [0] => Carbamate
            [1] => Trimethylammonium
        )

    [other_name] => Array
        (
        )

    [chemical_nomenclature] => N-p-chlorophenyl-N-methylcarbamate of m-hydroxyphenyltrimethylammonium bromide
    [formula] => C17H20N2O2ClBr
    [cas_number] => 
    [mw] => 399,71
    [pick_me_to_call] => display_script
    [kinetic_parameter] => 
    [paper] => Blaschko_1949_Br.J.Pharmacol_4_29 || Burn_1954_J.Physiol_124_489 || Casier_1952_Arch.Int.Pharmacodyn.Ther_90_412
    [comment] => 
    [gene_locus] => 
    [kin_inhibitor] => 
    [cid] => 
    [family] => ACHE
    [inchikey] => PCQGALCVXJWHNH-UHFFFAOYSA-M
    [canonicalsmiles] => C1=C(C=CC=C1OC(N(C)C2=CC=C(C=C2)Cl)=O)[N+](C)(C)C.[Br-]
    [inchi] => InChI=1S\/C17H20ClN2O2.BrH\/c1-19(14-10-8-13(18)9-11-14)17(21)22-16-7-5-6-15(12-16)20(2,3)4\;\/h5-12H,1-4H3\;1H\/q+1\;\/p-1
    [wikipedia] => 
    [iupharlig] => 
    [structure] => 
    [substrate] => 
    [interact_gene_locus] => 
    [mutation] => 
    [comment2] => 
    [extoxnet] => 
    [news] => 
    [theoretical_model] => 
)