Levamisole

cholinergic agonist used as nematicid; very low inhibitor of AChE

General

Type : Not A\/B H target,Anthelmintic,Azabicyclo,Sulfur Compound

Chemical_Nomenclature : (7S)-7-phenyl-4-thia-1,6-diazabicyclo[3.3.0]oct-5-ene

Canonical SMILES : C1CSC2=NC(CN21)C3=CC=CC=C3

InChI : InChI=1S\/C11H12N2S\/c1-2-4-9(5-3-1)10-8-13-6-7-14-11(13)12-10\/h1-5,10H,6-8H2\/t10-\/m1\/s1

InChIKey : HLFSDGLLUJUHTE-SNVBAGLBSA-N

Other name(s) : Ergamisol,Levamisol,Tramisol,Wormicid,Lepuron,Ketrax,L-Tetramisole,(-)-Tetramisole,L(-)-Levamisole


MW : 204.292

Formula : C11H12N2S

CAS_number :

PubChem : 26879

UniChem : HLFSDGLLUJUHTE-SNVBAGLBSA-N

IUPHAR : 7210

Wikipedia : Levamisole

Target

Families : Levamisole ligand of proteins in family
ACHE

References (1)

Title : Economic value and course of infection after treatment of cattle having a low level of nematode parasitism - Leland_1980_Am.J.Vet.Res_41_623
Author(s) : Leland SE, Jr. , Davis GV , Caley HK , Arnett DW , Ridley RK
Ref : American Journal of Veterinary Research , 41 :623 , 1980
Abstract : Leland_1980_Am.J.Vet.Res_41_623
ESTHER : Leland_1980_Am.J.Vet.Res_41_623
PubMedSearch : Leland_1980_Am.J.Vet.Res_41_623
PubMedID: 6447467
Array
(
    [id] => 5307
    [inhibitor] => Levamisole
    [type] => Array
        (
            [0] => Not A\/B H target
            [1] => Anthelmintic
            [2] => Azabicyclo
            [3] => Sulfur Compound
        )

    [other_name] => Array
        (
            [0] => Ergamisol
            [1] => Levamisol
            [2] => Tramisol
            [3] => Wormicid
            [4] => Lepuron
            [5] => Ketrax
            [6] => L-Tetramisole
            [7] => (-)-Tetramisole
            [8] => L(-)-Levamisole
        )

    [chemical_nomenclature] => (7S)-7-phenyl-4-thia-1,6-diazabicyclo[3.3.0]oct-5-ene
    [formula] => C11H12N2S
    [cas_number] => 
    [mw] => 204.292
    [pick_me_to_call] => display_script
    [kinetic_parameter] => 
    [paper] => Leland_1980_Am.J.Vet.Res_41_623
    [comment] => cholinergic agonist used as nematicid\; very low inhibitor of AChE
    [gene_locus] => 
    [kin_inhibitor] => 
    [cid] => 26879
    [family] => ACHE
    [inchikey] => HLFSDGLLUJUHTE-SNVBAGLBSA-N
    [canonicalsmiles] => C1CSC2=NC(CN21)C3=CC=CC=C3
    [inchi] => InChI=1S\/C11H12N2S\/c1-2-4-9(5-3-1)10-8-13-6-7-14-11(13)12-10\/h1-5,10H,6-8H2\/t10-\/m1\/s1
    [wikipedia] => Levamisole
    [iupharlig] => 7210
    [structure] => 
    [substrate] => 
    [interact_gene_locus] => 
    [mutation] => 
    [comment2] => 
    [extoxnet] => 
    [news] => 
    [theoretical_model] => 
)