OP5

AChE (IC50 = 7.34 microM) and Abeta aggregation (5 - 10 microM of peptide shows a significant reduction of Abeta aggregation)

General

Type : Peptide

Chemical_Nomenclature :

Canonical SMILES :

InChI :

InChIKey :

Other name(s) : NFDVLTEQ


MW : 965,03

Formula : C42H64N10O16

CAS_number :

PubChem :

UniChem :

IUPHAR :

Wikipedia :

Target

Families : OP5 ligand of proteins in family: ACHE

Stucture :

Protein :

References (1)

Title : Peptide-Based Acetylcholinesterase Inhibitor Crosses the Blood-Brain Barrier and Promotes Neuroprotection - Mondal_2018_ACS.Chem.Neurosci_9_2838
Author(s) : Mondal P , Gupta V , Das G , Pradhan K , Khan J , Gharai PK , Ghosh S
Ref : ACS Chem Neurosci , 9 :2838 , 2018
Abstract : Mondal_2018_ACS.Chem.Neurosci_9_2838
ESTHER : Mondal_2018_ACS.Chem.Neurosci_9_2838
PubMedSearch : Mondal_2018_ACS.Chem.Neurosci_9_2838
PubMedID: 30015476