Gene_Locus | Enzyme | Km | Kcat | Exp. conditions | Reference |
---|---|---|---|---|---|
human-BCHE | D70G | 9000 uM | 33200 /min | Lockridge_1990_Pharmacol.Ther_47_35 |
Title : Does butyrylization of acetylcholinesterase through substitution of the six divergent aromatic amino acids in the active center gorge generate an enzyme mimic of butyrylcholinesterase? - Kaplan_2001_Biochemistry_40_7433 |
Author(s) : Kaplan D , Ordentlich A , Barak D , Ariel N , Kronman C , Velan B , Shafferman A |
Ref : Biochemistry , 40 :7433 , 2001 |
Abstract : |
PubMedSearch : Kaplan_2001_Biochemistry_40_7433 |
PubMedID: 11412096 |
Title : The 'aromatic patch' of three proximal residues in the human acetylcholinesterase active centre allows for versatile interaction modes with inhibitors - Ariel_1998_Biochem.J_335_95 |
Author(s) : Ariel N , Ordentlich A , Barak D , Bino T , Velan B , Shafferman A |
Ref : Biochemical Journal , 335 :95 , 1998 |
Abstract : |
PubMedSearch : Ariel_1998_Biochem.J_335_95 |
PubMedID: 9742217 |