Gene Locus : human-BCHE
Mode of mutation : Site directed mutagenesis
Disease :
Summary : Active mutant Lushchekina_2016_Chem.Biol.Interact_259_223
AAA Change :
Allelic Variant :
Risk Factor :
Inhibitor :
Structure :
Disease by interaction :
Interact Gene Locus :
Xenobiotic sensitivity :
Modification :
Torpedo_number : 330
Kinetic Parameter : No kinetic parameter
News : No news
Comment :
p.A328C Ala328Cys (p.A356C Ala356Cys in primary sequence with 28 amino-acids signal peptide) catalically active mutant used in comparison of the silent variant p.Ala328Asp
Title : Understanding the non-catalytic behavior of human butyrylcholinesterase silent variants: comparison of wild-type enzyme, catalytically active Ala328Cys mutant, and silent Ala328Asp variant - Lushchekina_2016_Chem.Biol.Interact_259_223 |
Author(s) : Lushchekina SV , Nemukhin AV , Varfolomeev SD , Masson P |
Ref : Chemico-Biological Interactions , 259 :223 , 2016 |
Abstract : |
PubMedSearch : Lushchekina_2016_Chem.Biol.Interact_259_223 |
PubMedID: 27062896 |