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human-BCHE

Homo sapiens (Human) butyrylcholinesterase

Comment

Acylcholine acylhydrolase, Butyrylcholine esterase, Choline esterase II, Pseudocholinesterase. Esterase with broad substrate specificity. Contributes to the inactivation of the neurotransmitter acetylcholine. Can degrade neurotoxic organophosphate esters. BChE deficiency is a metabolic disorder characterized by prolonged apnoea after the use of certain anesthetic drugs, including the muscle relaxants succinylcholine or mivacurium and other ester local anesthetics.Various autosomal recessive mutations of the gene exist in human population || Another short contig contains a little bit of the gene AC069210.7.15194.32648 || Cterminus T peptide

Relationship

Family : BCHE

Block : C

Position in NCBI Life Tree : Homo sapiens

(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.)

> cellular organisms N E > Eukaryota N E > Opisthokonta N E > Metazoa N E > Eumetazoa N E > Bilateria N E > Deuterostomia N E > Chordata N E > Craniata N E > Vertebrata N E > Gnathostomata N E > Teleostomi N E > Euteleostomi N E > Sarcopterygii N E > Dipnotetrapodomorpha N E > Tetrapoda N E > Amniota N E > Mammalia N E > Theria N E > Eutheria N E > Boreoeutheria N E > Euarchontoglires N E > Primates N E > Haplorrhini N E > Simiiformes N E > Catarrhini N E > Hominoidea N E > Hominidae N E > Homininae N E > Homo N E > Homo sapiens N E

Molecular evidence

3q26.1del_human-BCHE A184V_human-BCHE A199S\/F227A\/P285A\/S287G\/A328W\/Y332G_human-BCHE A199S\/F227A\/S287G\/A328W\/E441D_human-BCHE A199S\/F227A\/S287G\/A328W\/Y332G\/F329V_human-BCHE A199S\/F227A\/S287G\/A328W\/Y332G\/F364C\/M532C_human-BCHE A199S\/F227A\/S287G\/A328W\/Y332G\/N535C_human-BCHE A199S\/F227A\/S287G\/A328W\/Y332G\/V377C\/A516C_human-BCHE A199S\/F227A\/S287G\/A328W\/Y332G_human-BCHE A199S\/F227I\/S287G\/A328W\/Y332G_human-BCHE A199S\/F227L\/S287G\/A328W\/Y332G_human-BCHE A199S\/F227S\/S287G\/A328W\/Y332G_human-BCHE A199S\/F227V\/S287G\/A328W\/Y332G_human-BCHE A199S\/S287G\/A328W\/Y332G\/L286I_human-BCHE A199S\/S287G\/A328W\/Y332G_human-BCHE A199V_human-BCHE A201T_human-BCHE A277H_human-BCHE A277V_human-BCHE A277W\/G283D_human-BCHE A277W_human-BCHE A328C_human-BCHE A328D_human-BCHE A328F_human-BCHE A328G\/F329S_human-BCHE A328G_human-BCHE A328W\/Y332A\/Y419S_human-BCHE A328W\/Y332A_human-BCHE A328W\/Y332G_human-BCHE A328W_human-BCHE A328Y_human-BCHE A34V_human-BCHE A459E_human-BCHE A539T_human-BCHE A7T_human-BCHE Alu-ins1_human-BCHE Alu-ins2_human-BCHE C400X_human-BCHE C571A_human-BCHE C66M_human-BCHE D170E_human-BCHE D340H_human-BCHE D379E_human-BCHE D391E_human-BCHE D454L_human-BCHE D54G_human-BCHE D70G\/A539T_human-BCHE D70G\/E441G\/E443Q_human-BCHE D70G\/F561Y_human-BCHE D70G\/S425P_human-BCHE D70G\/Y114H\/F561Y_human-BCHE D70G\/Y114H\/S425P_human-BCHE D70G\/Y114H_human-BCHE D70G\/Y332A_human-BCHE D70G_human-BCHE D70H_human-BCHE D70K_human-BCHE D70N_human-BCHE D70Y\/Y332D_human-BCHE D70Y_human-BCHE E197C_human-BCHE E197D_human-BCHE E197G_human-BCHE E197Q\/F329S_human-BCHE E197Q_human-BCHE E255D_human-BCHE E271X_human-BCHE E387D_human-BCHE E432X_human-BCHE E441G\/E443Q_human-BCHE E451X_human-BCHE E460K_human-BCHE E497V\/A539T_human-BCHE E497V_human-BCHE E90D_human-BCHE F118VfsX11_human-BCHE F227A\/S287G\/A328W\/Y332M_human-BCHE F227A_human-BCHE F28I_human-BCHE F329A_human-BCHE F329C_human-BCHE F329D_human-BCHE F329L_human-BCHE F329Q_human-BCHE F329S_human-BCHE F409Y_human-BCHE F417Y_human-BCHE F418S_human-BCHE F446V_human-BCHE F474L_human-BCHE F521X_human-BCHE F525X_human-BCHE F526X_human-BCHE F561Y_human-BCHE G115A_human-BCHE G115C_human-BCHE G115D_human-BCHE G115E_human-BCHE G115H_human-BCHE G115S_human-BCHE G116A\/G117D_human-BCHE G116E_human-BCHE G117C_human-BCHE G117D_human-BCHE G117E_human-BCHE G117H\/E197Q_human-BCHE G117H_human-BCHE G117K_human-BCHE G117N_human-BCHE G117R_human-BCHE G117S_human-BCHE G117Y_human-BCHE G121H_human-BCHE G283D_human-BCHE G283S_human-BCHE G333C_human-BCHE G360N_human-BCHE G365R_human-BCHE G390A_human-BCHE G390V_human-BCHE G439S_human-BCHE G534X_human-BCHE G75R_human-BCHE H126CfsX2_human-BCHE H126P_human-BCHE H77L_human-BCHE I111V_human-BCHE I305T_human-BCHE I345T_human-BCHE I356V_human-BCHE I4del_human-BCHE I5T_human-BCHE I6LfsX9_human-BCHE I99M_human-BCHE IVS2E3-8G_human-BCHE IVS3E4-14C_human-BCHE K-4X_human-BCHE K12R_human-BCHE K180D_human-BCHE K190N_human-BCHE K267R_human-BCHE K339M_human-BCHE K469R_human-BCHE K528X_human-BCHE K544H\/R549H\/K558H\/K568H\/K569H_human-BCHE K558H\/K568H\/K569H_human-BCHE K568H\/K569H_human-BCHE L110M_human-BCHE L125F_human-BCHE L125V_human-BCHE L156S_human-BCHE L236P_human-BCHE L274D_human-BCHE L286D_human-BCHE L286H_human-BCHE L286K_human-BCHE L286Q_human-BCHE L286R_human-BCHE L307P_human-BCHE L330I_human-BCHE L530X_human-BCHE L574SfsX2_human-BCHE M1T_human-BCHE M434I_human-BCHE M437D_human-BCHE N106KfsX22_human-BCHE N17Q\/N455Q\/N481Q\/N486Q\/L530X_human-BCHE N188D_human-BCHE N322E\/E325G_human-BCHE N342D_human-BCHE N397F_human-BCHE N68A_human-BCHE N68D_human-BCHE N68K_human-BCHE N68R_human-BCHE N68Y_human-BCHE N83A_human-BCHE N83Q_human-BCHE N96Y_human-BCHE P100S_human-BCHE P285L_human-BCHE P37S_human-BCHE P527X_human-BCHE PYGTP281-284EPYNGTA\/G117H_human-BCHE Q119A_human-BCHE Q119E_human-BCHE Q119G_human-BCHE Q119H_human-BCHE Q119K_human-BCHE Q119R_human-BCHE Q119X_human-BCHE Q119Y_human-BCHE Q172X_human-BCHE Q176K_human-BCHE Q380D_human-BCHE Q518H_human-BCHE Q518L_human-BCHE Q71T_human-BCHE R386C_human-BCHE R424X_human-BCHE R465X_human-BCHE R470W_human-BCHE R515C_human-BCHE R549H_human-BCHE S191R_human-BCHE S198C_human-BCHE S198D_human-BCHE S198G_human-BCHE S198H_human-BCHE S198Q_human-BCHE S203P_human-BCHE S215P_human-BCHE S410A_human-BCHE S425P_human-BCHE S466E_human-BCHE S489Q_human-BCHE S48P_human-BCHE S495P_human-BCHE S524X_human-BCHE T120E_human-BCHE T120G_human-BCHE T120H_human-BCHE T120K_human-BCHE T234M_human-BCHE T243M_human-BCHE T24M_human-BCHE T250L_human-BCHE T250P_human-BCHE T284H\/P285T\/L286I\/S287H\/V288G_human-BCHE T284N\/P285H\/L286I\/V288G_human-BCHE T284N\/P285K\/L286S\/S287N_human-BCHE T284P\/P285S\/L286H\/V288G_human-BCHE T284P\/S287R\/V288S_human-BCHE T284Q\/P285S\/L286I\/S287H\/V288I_human-BCHE T315NfsX7_human-BCHE T315S_human-BCHE T406A_human-BCHE T508S_human-BCHE T523N_human-BCHE T523X_human-BCHE V127D_human-BCHE V142M_human-BCHE V178I_human-BCHE V204D_human-BCHE V288H_human-BCHE V294M_human-BCHE V377E_human-BCHE V393A_human-BCHE V468M_human-BCHE W231A_human-BCHE W231S_human-BCHE W412H_human-BCHE W430A_human-BCHE W471R_human-BCHE W490R_human-BCHE W522X_human-BCHE W543A\/F547A\/W550A\/Y553A\/W557A\/F561A\/Y564A\/C571A_human-BCHE W543A\/F547A\/W550A\/Y553A\/W557A\/F561A\/Y564A_human-BCHE W82A_human-BCHE W82F_human-BCHE W82Y_human-BCHE WT_human-BCHE Y128C_human-BCHE Y237E_human-BCHE Y332A_human-BCHE Y332D_human-BCHE Y332F_human-BCHE Y332S\/D340H_human-BCHE Y332S_human-BCHE Y33C_human-BCHE Y440D_human-BCHE Y500X_human-BCHE YGTP282-285NHML_human-BCHE c-116G>A_human-BCHE c1914G>A_human-BCHE

1P0I - Crystal structure of human butyrylcholinesterase 1P0M - Crystal structure of human butyrylcholinesterase in complexe with a choline molecule 1P0P - Crystal structure of soman-aged human butyrylcholinesterase in complex with the substrate analog butyrylthiocholine 1P0Q - Crystal structure of soman-aged human butyrylcholinesterase 1XLU - X-Ray Structure Of Aged Di-Isopropyl-Phosphoro-Fluoridate (Dfp) Bound To Butyrylcholinesterase 1XLV - Ethylphosphorylated Butyrylcholinesterase (Aged) Obtained By Reaction With Echothiophate. 1XLW - Diethylphosphorylated Butyrylcholinesterase (Nonaged) Obtained By Reaction With Echothiophate 2J4C - Structure of human Butyrylcholinesterase in complex with 10mM HgCl2 2PM8 - Crystal structure of recombinant full length human butyrylcholinesterase 2WID - Non aged form of human butyrylcholinesterase inhibited by tabun analogue TA1 2WIF - Aged form of human butyrylcholinesterase inhibited by tabun analogue TA1 2WIG - Non aged form of human butyrylcholinesterase inhibited by tabun analogue TA4 2WIJ - Non aged form of human butyrylcholinesterase inhibited by tabun analogue TA5 2WIK - Non aged form of human butyrylcholinesterase inhibited by tabun analogue TA6 2WIL - Aged form of human butyrylcholinesterase inhibited by tabun analogue TA5 2WSL - Aged form of human butyrylcholinesterase inhibited by tabun analogue TA4 2XMB - G117H mutant of human butyrylcholinesterase in complex with sulfate 2XMC - G117H mutant of human butyrylcholinesterase in complex with fluoride anion 2XMD - G117H mutant of human butyrylcholinesterase in complex with echothiophate 2XMG - G117H mutant of human butyrylcholinesterase in complex with VX 2XQF - X-ray Structure of human butyrylcholinesterase inhibited by racemic VX 2XQG - X-ray Structure of human butyrylcholinesterase inhibited by racemic VR 2XQI - X-ray Structure of human butyrylcholinesterase inhibited by racemic CVX 2XQJ - X-ray Structure of human butyrylcholinesterase inhibited by pure enantiomer VX-(R) 2XQK - X-ray Structure of human butyrylcholinesterase inhibited by pure enantiomer VX-(S) 2Y1K - Structure of Human Butyrylcholinesterase Inhibited by CBDP (12h soak) : Phosphoserine Adduct 3DJY - Nonaged Form of Human Butyrylcholinesterase Inhibited by Tabun 3DKK - Aged Form of Human Butyrylcholinesterase Inhibited by Tabun 3O9M - Co-crystallization studies of full length recombinant BChE with cocaine offers insights into cocaine detoxification 4AQD - Crystal structure of fully glycosylated human butyrylcholinesterase 4AXB - Crystal structure of soman-aged human butyrylcholinesterase in complex with 2-PAM 4B0O - Crystal structure of soman-aged human butyrylcholinesterase in complex with benzyl pyridinium-4-methyltrichloroacetimidate 4B0P - Crystal structure of soman-aged human butyrylcholinesterase in complex with methyl 2-(pentafluorobenzyloxyimino)pyridinium 4BBZ - Structure of human butyrylcholinesterase inhibited by CBDP (2-min soak): Cresyl-phosphoserine adduct 4BDS - Human butyrylcholinesterase in complex with tacrine 4TPK - Human butyrylcholinesterase in complex with N-((1-(2,3-dihydro-1H-inden-2-yl)piperidin-3-yl)methyl)-N-(2-methoxyethyl)-2-naphthamide 4XII - X-ray structure of human butyrylcholinesterase complex with 3-pyridin-4-yl-2,4-dihydro-indeno[1,2-.C.]pyrazole 5DYT - Crystal structure of human butyrylcholinesterase in complex with N-((1-benzylpiperidin-3-yl)methyl)-N-methylnaphthalene-2-sulfonamide 5DYW - Crystal structure of human butyrylcholinesterase in complex with N-((1-benzylpiperidin-3-yl)methyl)-N-(2-methoxyethyl)naphthalene-2-sulfonamide 5DYY - Crystal structure of human butyrylcholinesterase in complex with N-((1-benzylpiperidin-3-yl)methyl)naphthalene-2-sulfonamide 5K5E - Discovery and structure-activity relationships of a highly selective Butyrylcholinesterase inhibitor by structure-based virtual screening (5JYW withdrawn) 5LKR - Human Butyrylcholinesterase complexed with N-Propargyliperidine 5LKR-6yc 5NN0 - Human butyrylcholinesterase in complex with inhibitor with picomolar activity 6EMI - Crystal structure of a variant of human butyrylcholinesterase expressed in bacteria 6EP4 - Human butyrylcholinesterase in complex with decamethonium 6EQP - Human butyrylcholinesterase in complex with ethopropazine 6EQQ - Human butyrylcholinesterase in complex with huprine 19 6ESJ - Human butyrylcholinesterase in complex with propidium 6ESY - Human butyrylcholinesterase in complex with thioflavine T 6EYF - Butyrylcholinesterase expressed in CHO cells co-crystallised with a rivastigmine analogue (replaced 6EUL) 6EZ2 - Human butyrylcholinesterase carbamylated. supersedes 6EUK 6F7Q - Human Butyrylcholinesterase complexed with N-Propargyliperidines 6I0B - Human butyrylcholinesterase in complex with the R enantiomer of a chlorotacrine-tryptophan multi-target inhibitor 6I0C - Human butyrylcholinesterase in complex with the S enantiomer of a chlorotacrine-tryptophan multi-target inhibitor 6I2T - Model of full-length, fully-glycosylated human butyrylcholinesterase tetramer 6QAA - Human Butyrylcholinesterase in complex with (S)-2-(butylamino)-N-(2-cycloheptylethyl)-3-(1H-indol-3-yl)propanamide 6QAB - Human Butyrylcholinesterase in complex with (S)-N-(1-((2-cycloheptylethyl)amino)-3-(1H-indol-3-yl)-1-oxopropan-2-yl)-N,N-dimethylbutan-1-aminium 6QAC - Human Butyrylcholinesterase in complex with (S)-2-(butylamino)-N-(3-cycloheptylpropyl)-3-(1H-indol-3-yl)propanamide 6QAD - Human Butyrylcholinesterase in complex with ((S)-2-(butylamino)-N-(2-(4-(dimethylamino)cyclohexyl)ethyl)-3-(1H-indol-3-yl)propanamide 6QAE - Human Butyrylcholinesterase in complex with (S)-N2-butyl-N1-(2-cycloheptylethyl)-3-(1H-indol-3-yl)-N1,N2-dimethylpropane-1,2-diamine 6R6V - Structure of recombinant human butyrylcholinesterase in complex with a fluorescent coumarin-based probe 6R6W - Structure of recombinant human butyrylcholinesterase in complex with a fluorescent NBD-based probe 6RUA - Structure of recombinant human butyrylcholinesterase in complex with a coumarin-based fluorescent probe linked to sulfonamide type inhibitor 6SAM - Structure of human butyrylcholinesterase in complex with 1-(2,3-dihydro-1H-inden2-yl)piperidin-3-yl N-phenyl carbamate 6T9P - Structure of human butyrylcholinesterase in complex with R enantiomer of oxime III, methylimidazole derivative of 2-hydroxyimino-N-(azidophenylpropyl)acetamide 6T9S - Structure of human butyrylcholinesterase in complex with S enantiomer of oxime III, methylimidazole derivative of 2-hydroxyimino-N-(azidophenylpropyl)acetamide 6XTA - Human Butyrylcholinesterase in complex with compound 18 6ZWI - Human butyrylcholinesterase in complex with ((6-((2E,4E)-5-(benzo[d][1,3]dioxol-5-yl)penta-2,4-dienamido)hexyl)triphenylphosphonium bromide) 7AIY - Crystal structure of human butyrylcholinesterase in complex with 2-{1-[4-(12-Amino-3-chloro-6,7,10,11-tetrahydro-7,11-methanocycloocta[b]quinolin-9-yl)butyl]-1H-1,2,3-triazol-4-yl}-N-[4-hydroxy-3-methoxybenzyl]acetamide compound 5i 7AMZ - Human butyrylcholinesterase in complexe with N-((2S,3R)-3-hydr oxy-4-(neopentylamino)-1-phenylbutan-2-yl)-2,2-diphenylacetamide (51) 7AWG - Crystal structure of human butyrylcholinesterase in complex with compound 27 (2-((1-(benzenesulfonyl)-1H-indol-4-yl)oxy)ethyl)(benzyl)amine 7AWH - Crystal structure of human butyrylcholinesterase in complex with compound 54 tert-butyl 3-(((2-((1-(benzenesulfonyl)-1H-indol-4-yl)oxy)ethyl)amino)methyl)piperidine-1-carboxylate 7AWI - Crystal structure of human butyrylcholinesterase in complex with compound 70 tert-butyl 3-(((2-((1-benzyl-1H-indol-4-yl)oxy)ethyl)amino)methyl]piperidine-1-carboxylate 7BGC - Human Butyrylcholinesterase in complex with a tacrine-methylanacardate hybrid inhibitor 7BO3 - Human Butyrylcholinesterase in complex with N-(2-(1H-Indol-3-yl)ethyl)-2-cycloheptyl-N-methylethan-1-amine 7BO4 - Human Butyrylcholinesterase in complex with 3-(2-(butyl(2-cycloheptylethyl)amino)ethyl)-1H-indol-6-ol 7P86 - WITHDRAWN Crystal structure of human butyrylcholinesterase inibited by omethoate 7P89 - WITHDRAWN Crystal structure of human butyrylcholinesterase inibited by chlorpyrifos oxon 7Q1M - Crystal structure of human butyrylcholinesterase in complex with N-[(2S)-3-[(cyclohexylmethyl)amino]-2-hydroxypropyl]-2,2-diphenylacetamide 7Q1N - Crystal structure of human butyrylcholinesterase in complex with N-[(2R)-3-[(cyclohexylmethyl)amino]-2-hydroxypropyl]-2,2-diphenylacetamide 7Q1O - Crystal structure of human butyrylcholinesterase in complex with N-[(2S)-3-[(cyclohexylmethyl)amino]-2-hydroxypropyl]-3,3-diphenylpropanamide 7Q1P - Crystal structure of human butyrylcholinesterase in complex with N-[(2R)-3-[(cyclohexylmethyl)amino]-2-hydroxypropyl]-3,3-diphenylpropanamide 7QBQ - Human butyrylcholinesterase in complex with (Z)-N-benzyl-1-(8-hydroxyquinolin-2-yl)methanimine oxide 7QBR - Human butyrylcholinesterase in complex with (Z)-N-tert-butyl-1-(8-(3-(4-(prop-2-yn-1-yl)piperazin-1-yl)propoxy)quinolin-2-yl)methanimine oxide 7QHD - Human Butyrylcholinesterase in complex with (S)-1-(4-((2-(1H-indol-3-yl)ethyl)carbamoyl)benzyl)-N-(3-((1,2,3,4-tetrahydroacridin-9-yl)amino)propyl)piperidine-3-carboxamide, compound 39 7QHE - Human Butyrylcholinesterase in complex with (S)-1-(4-((naphthalen-1-yl)carbamoyl)benzyl)-N-(3-((1,2,3,4-tetrahydroacridin-9-yl)amino)propyl)piperidine-3-carboxamide, compound 43 7ZPB - Structure of hemiacetylated human butyrylcholinesterase upon reaction with 8-(3-(4-(prop-2-yn-1-yl)piperazin-1-yl)propoxy)quinoline-2-carbaldehyde 8AI7 - Human butyrylcholinesterase in complex with Cpd-6-8AI7 8AM1 - Human butyrylcholinesterase in complex with zinc and N,N,N-trimethyl-2-oxo-2-(2-(pyridin-2-ylmethylene)hydrazineyl)ethan-1-aminium 8AM2 - Human butyrylcholinesterase in complex with 2,2'-(((1E,1'E)-(2-phenylpyrimidine-4,6-diyl)bis(methaneylylidene))bis(hydrazin-1-yl-2-ylidene))bis(N,N,N-trimethyl-2-oxoethan-1-aminium) 8CGO - Structure of human butyrylcholinesterase in complex with N-{[2-(benzyloxy)-3-methoxyphenyl]methyl}-N-[3-(2-fluorophenyl)propyl]cyclobutanamine

1-Naphtylacetate_D70G_human-BCHE 1-Naphtylacetate_WT_human-BCHE 17-desoxypancuronium_D70G_human-BCHE 17-desoxypancuronium_WT_human-BCHE Acetylcholine_D70G_human-BCHE Acetylcholine_WT_human-BCHE Acetylthiocholine_WT_human-BCHE Aspirin_D70G_human-BCHE Aspirin_WT_human-BCHE BW284C51_D70G_human-BCHE BW284C51_G115A_human-BCHE BW284C51_G115S_human-BCHE BW284C51_G117E_human-BCHE BW284C51_N68A_human-BCHE BW284C51_N68D_human-BCHE BW284C51_N68K_human-BCHE BW284C51_N68R_human-BCHE BW284C51_N68Y_human-BCHE BW284C51_Q119A_human-BCHE BW284C51_Q119E_human-BCHE BW284C51_Q119G_human-BCHE BW284C51_Q119H_human-BCHE BW284C51_Q119K_human-BCHE BW284C51_Q119R_human-BCHE BW284C51_Q119Y_human-BCHE BW284C51_T120E_human-BCHE BW284C51_T120G_human-BCHE BW284C51_T120H_human-BCHE BW284C51_T120K_human-BCHE BW284C51_V127D_human-BCHE BW284C51_W82F_human-BCHE BW284C51_W82Y_human-BCHE BW284C51_WT_human-BCHE Bambuterol_WT_human-BCHE Benzoylcholine_D70G_human-BCHE Benzoylcholine_F525X_human-BCHE Benzoylcholine_WT_human-BCHE Butyrylcholine_D70G_human-BCHE Butyrylcholine_WT_human-BCHE Butyrylthiocholine_D70G_human-BCHE Butyrylthiocholine_F329C_human-BCHE Butyrylthiocholine_F329D_human-BCHE Butyrylthiocholine_F329L_human-BCHE Butyrylthiocholine_F329Q_human-BCHE Butyrylthiocholine_F525X_human-BCHE Butyrylthiocholine_G115A_human-BCHE Butyrylthiocholine_G115C_human-BCHE Butyrylthiocholine_G115D_human-BCHE Butyrylthiocholine_G115E_human-BCHE Butyrylthiocholine_G115S_human-BCHE Butyrylthiocholine_G116A\/G117D_human-BCHE Butyrylthiocholine_G116E_human-BCHE Butyrylthiocholine_G117D_human-BCHE Butyrylthiocholine_G117E_human-BCHE Butyrylthiocholine_L286D_human-BCHE Butyrylthiocholine_L286K_human-BCHE Butyrylthiocholine_L286Q_human-BCHE Butyrylthiocholine_L286R_human-BCHE Butyrylthiocholine_N68A_human-BCHE Butyrylthiocholine_N68D_human-BCHE Butyrylthiocholine_N68K_human-BCHE Butyrylthiocholine_N68R_human-BCHE Butyrylthiocholine_N68Y_human-BCHE Butyrylthiocholine_Q119A_human-BCHE Butyrylthiocholine_Q119E_human-BCHE Butyrylthiocholine_Q119G_human-BCHE Butyrylthiocholine_Q119H_human-BCHE Butyrylthiocholine_Q119K_human-BCHE Butyrylthiocholine_Q119R_human-BCHE Butyrylthiocholine_Q119Y_human-BCHE Butyrylthiocholine_T120E_human-BCHE Butyrylthiocholine_T120G_human-BCHE Butyrylthiocholine_T120H_human-BCHE Butyrylthiocholine_T120K_human-BCHE Butyrylthiocholine_V127D_human-BCHE Butyrylthiocholine_W82F_human-BCHE Butyrylthiocholine_W82Y_human-BCHE Butyrylthiocholine_WT_human-BCHE Butyrylthiocholine_Y440D_human-BCHE Chlorpromazine_D70G_human-BCHE Chlorpromazine_WT_human-BCHE Choline_D70G_human-BCHE Choline_WT_human-BCHE Cocaine_D70G_human-BCHE Cocaine_G115A_human-BCHE Cocaine_G115S_human-BCHE Cocaine_G117E_human-BCHE Cocaine_N68K_human-BCHE Cocaine_N68R_human-BCHE Cocaine_Q119K_human-BCHE Cocaine_Q119R_human-BCHE Cocaine_T120K_human-BCHE Cocaine_W82F_human-BCHE Cocaine_W82Y_human-BCHE Cocaine_WT_human-BCHE DFP_F329C_human-BCHE DFP_F329D_human-BCHE DFP_F329L_human-BCHE DFP_F329Q_human-BCHE DFP_L286D_human-BCHE DFP_L286Q_human-BCHE DFP_WT_human-BCHE DFP_Y440D_human-BCHE Decamethonium_D70G_human-BCHE Decamethonium_WT_human-BCHE Dibucaine_D70G_human-BCHE Dibucaine_G115A_human-BCHE Dibucaine_G115S_human-BCHE Dibucaine_G117E_human-BCHE Dibucaine_N68A_human-BCHE Dibucaine_N68D_human-BCHE Dibucaine_N68K_human-BCHE Dibucaine_N68R_human-BCHE Dibucaine_N68Y_human-BCHE Dibucaine_Q119A_human-BCHE Dibucaine_Q119E_human-BCHE Dibucaine_Q119G_human-BCHE Dibucaine_Q119H_human-BCHE Dibucaine_Q119K_human-BCHE Dibucaine_Q119R_human-BCHE Dibucaine_Q119Y_human-BCHE Dibucaine_T120E_human-BCHE Dibucaine_T120G_human-BCHE Dibucaine_T120H_human-BCHE Dibucaine_T120K_human-BCHE Dibucaine_V127D_human-BCHE Dibucaine_W82F_human-BCHE Dibucaine_W82Y_human-BCHE Dibucaine_WT_human-BCHE Dibutyrate-pancuronium_D70G_human-BCHE Dibutyrate-pancuronium_WT_human-BCHE Echothiophate_F329C_human-BCHE Echothiophate_F329D_human-BCHE Echothiophate_F329L_human-BCHE Echothiophate_F329Q_human-BCHE Echothiophate_L286D_human-BCHE Echothiophate_L286K_human-BCHE Echothiophate_L286Q_human-BCHE Echothiophate_WT_human-BCHE Echothiophate_Y440D_human-BCHE Edrophonium_WT_human-BCHE Heptanoylcholine_D70G_human-BCHE Heptanoylcholine_WT_human-BCHE Heroin_D70G_human-BCHE Heroin_WT_human-BCHE Hexanoylcholine_D70G_human-BCHE Hexanoylcholine_WT_human-BCHE HuperzineA_WT_human-BCHE Iso-OMPA_F329C_human-BCHE Iso-OMPA_F329D_human-BCHE Iso-OMPA_F329L_human-BCHE Iso-OMPA_F329Q_human-BCHE Iso-OMPA_L286D_human-BCHE Iso-OMPA_L286K_human-BCHE Iso-OMPA_L286Q_human-BCHE Iso-OMPA_WT_human-BCHE Iso-OMPA_Y440D_human-BCHE Meperidine_D70G_human-BCHE Meperidine_WT_human-BCHE Methylprednisolone-acetate_D70G_human-BCHE Methylprednisolone-acetate_WT_human-BCHE Neostigmine~Prostigmine_D70G_human-BCHE Neostigmine~Prostigmine_WT_human-BCHE O-Nitrophenylbutyrate_D70G_human-BCHE O-Nitrophenylbutyrate_F525X_human-BCHE O-Nitrophenylbutyrate_WT_human-BCHE Pancuronium_D70G_human-BCHE Pancuronium_WT_human-BCHE Paraoxon_G117H_human-BCHE Pentanoylcholine_D70G_human-BCHE Pentanoylcholine_WT_human-BCHE Physostigmine~Eserine_D70G_human-BCHE Physostigmine~Eserine_WT_human-BCHE Procaine_D70G_human-BCHE Procaine_WT_human-BCHE Propionylcholine_D70G_human-BCHE Propionylcholine_WT_human-BCHE Ro-2-0683_D70G_human-BCHE Ro-2-0683_WT_human-BCHE Solanine_D70G_human-BCHE Solanine_G115A_human-BCHE Solanine_G115S_human-BCHE Solanine_G117E_human-BCHE Solanine_N68A_human-BCHE Solanine_N68D_human-BCHE Solanine_N68K_human-BCHE Solanine_N68R_human-BCHE Solanine_N68Y_human-BCHE Solanine_Q119A_human-BCHE Solanine_Q119E_human-BCHE Solanine_Q119G_human-BCHE Solanine_Q119H_human-BCHE Solanine_Q119K_human-BCHE Solanine_Q119R_human-BCHE Solanine_Q119Y_human-BCHE Solanine_T120E_human-BCHE Solanine_T120G_human-BCHE Solanine_T120H_human-BCHE Solanine_T120K_human-BCHE Solanine_V127D_human-BCHE Solanine_W82F_human-BCHE Solanine_W82Y_human-BCHE Solanine_WT_human-BCHE Succinylcholine~Suxamethonium_D70G_human-BCHE Succinylcholine~Suxamethonium_G115A_human-BCHE Succinylcholine~Suxamethonium_G115S_human-BCHE Succinylcholine~Suxamethonium_G117E_human-BCHE Succinylcholine~Suxamethonium_N68A_human-BCHE Succinylcholine~Suxamethonium_N68D_human-BCHE Succinylcholine~Suxamethonium_N68K_human-BCHE Succinylcholine~Suxamethonium_N68R_human-BCHE Succinylcholine~Suxamethonium_N68Y_human-BCHE Succinylcholine~Suxamethonium_Q119A_human-BCHE Succinylcholine~Suxamethonium_Q119E_human-BCHE Succinylcholine~Suxamethonium_Q119G_human-BCHE Succinylcholine~Suxamethonium_Q119H_human-BCHE Succinylcholine~Suxamethonium_Q119K_human-BCHE Succinylcholine~Suxamethonium_Q119R_human-BCHE Succinylcholine~Suxamethonium_Q119Y_human-BCHE Succinylcholine~Suxamethonium_T120E_human-BCHE Succinylcholine~Suxamethonium_T120G_human-BCHE Succinylcholine~Suxamethonium_T120H_human-BCHE Succinylcholine~Suxamethonium_T120K_human-BCHE Succinylcholine~Suxamethonium_V127D_human-BCHE Succinylcholine~Suxamethonium_W82F_human-BCHE Succinylcholine~Suxamethonium_W82Y_human-BCHE Succinylcholine~Suxamethonium_WT_human-BCHE Succinyldithiocholine_D70G_human-BCHE Succinyldithiocholine_WT_human-BCHE Tacrine_D70G_human-BCHE Tacrine_G115A_human-BCHE Tacrine_G115S_human-BCHE Tacrine_G117E_human-BCHE Tacrine_N68A_human-BCHE Tacrine_N68D_human-BCHE Tacrine_N68K_human-BCHE Tacrine_N68R_human-BCHE Tacrine_N68Y_human-BCHE Tacrine_Q119A_human-BCHE Tacrine_Q119E_human-BCHE Tacrine_Q119G_human-BCHE Tacrine_Q119H_human-BCHE Tacrine_Q119K_human-BCHE Tacrine_Q119R_human-BCHE Tacrine_Q119Y_human-BCHE Tacrine_T120E_human-BCHE Tacrine_T120G_human-BCHE Tacrine_T120H_human-BCHE Tacrine_T120K_human-BCHE Tacrine_V127D_human-BCHE Tacrine_W82F_human-BCHE Tacrine_W82Y_human-BCHE Tacrine_WT_human-BCHE Tetracaine_D70G_human-BCHE Tetracaine_WT_human-BCHE Tetramethylammonium_D70G_human-BCHE Tetramethylammonium_WT_human-BCHE Vecuronium_D70G_human-BCHE Vecuronium_WT_human-BCHE Win4510_WT_human-BCHE Win4510_human-BCHE Win5303_D70G_human-BCHE Win5303_WT_human-BCHE

No disease

(-)-phenethylcymserine (R)-37a 1,9-dimethyl-methylene-blue 10c-Salicylimine-Tacrine 123I-PIP 1d-phosphoryl-dihydroacridine 2-Chloroprocaine 3,5-dihydroxybenzamido-huprine-hybrid-11 3F9 40V 5-deoxo-3-hydroxyevodiamine-heptyl-carbamate 5-pyrid-3-yl-1,3,4-oxadiazole-5e 5DYT-5hb 5DYW-5hf 5DYW-5hf-C11 5DYW-5hf-F 5DYY-5hh 5LKR-6yc 5NN0-cpd3 6-(2-phenylethyl)-THAI-12b 6-(4-4-phenethylpiperazin-1-yl)heptyl-THAI-14d 6EUL-BY2 6F7Q-cpd11 6H6-Heptyl-Carbamate 6QAA-HUN 6QAB-HUQ 6QAC-HUT 6QAD-HUZ 6QAE-HUK 6RUA-3a 6SAM-cpd13 6XTA-cpd18 6ZWE-Cpd3 6o-5-HT3 7-Methyloxyde-PhO-cpd-I52 7-PhO-THA 8012-9656 8AM2-N0C 8IS-7Q1M 8IV-7Q1N 8U2-7AIX7AY-compound5i 8UW-7Q1P 9CI-7Q1O A87-7BO4 AI0-7QBQ AI6-7QBR Aminoalkyl-tetrahydropyrimido-azocine-7c Amiridine-Admantyl-5d Amiridine-thiouracil-13c Aprophen Aromatic-tertiary-amine-17c Aroylacrylic-acid-amide-Tacrine-10 Aryl-carboxamide-benzoxazole-cpd36 Ass-IN-10 BChE-HDAC6-IN-1 BChE-HDAC6-IN-2 BChE-IN-21 BChE-IN-3 BChE-IN-9 Benactyzine Benzimidazole-Diethylcarbamoyl-isopentyl-dimethylcarbamate-15d Benzimidazole-Ethoxybenzyl-isopentyl-azetidine-carboxylate-21d Benzimidazole-phenyl-azetidine-carboxylate-11d Benzyl-2-triazole-linked-tryptamine-paeonol-Cpd896 Benzyloxy-benzylamino-Carltonine-Cpd28 Benzyloxy-benzylamino-Carltonine-Cpd33 Benzylpiperidin-methylsulfonyl-indol-acryloyl-phenyl-acetamide-cpd6b Bis-alkylene-Amiridine-3c Biscarbamate-Cpd16 BuChE-IN-TM-10 C0I-7QHD C4I-7QHE CBD-carbamate-C16 CBDP CHEMBL4079247 CHEMBL4177075-INDY CHEMBL4207101 CHEMBL4442990 CHEMBL4454960 CHEMBL4454960-PET CHEMBL4456083 CHEMBL459756 CHEMBL4793341 Caffeic-acid-phenethyl-ester Cannabidiol-amide-CB7 Carltonine-A Carltonine-B ChEs-MAOs-IN-1 Chinese-VX Chlorophenyl-methylsulfonyl-indol-acryloyl-phenyl-acetamide-cpd5b Chlorotacrine-tryptophan-hybrid Choline Cocaine Coumarin-Pyridine-3f Coumarin-phosphazide-Cpd8b Cpd-17-Cycloheptyl-Indole-undecyl-carbamate Cpd-6-8AI7 Cpd20-Benzimidazol-Oxadiazol Cyclohexylmethylcarbamate-phenethylnorphysostigmine-3u DFP DL0410 Decamethonium Di-tert-butyl-phenol-octylamino-cycloheptaquinolin-18d Diethoxyphosphoryloxy-oleanolic-acid Difluorophenyl-pyridin-piperazin-1,3,4-oxadiazole-49 Dihydrobenzodioxepine-cymeserine Dimethylhydroxycarbaphen Donepezil-idebenone-cpd9 Echothiophate Ethopropazine Ethylpiperidinyl-ethyl-indole-Cpd19 FUB833 Fluoride Fluoro-piperidin-ethyl-carbazole-15g Fmoc-Lys(Boc)-trimethylammonium-5e Gamma-carboline-nonyl-bivalent Gamma-carboline-phenothiazine-Cpd7b Goodyschle-A H327 Hup-19 IA4-7BO3 Idalopirdine-rivastigmine Indazole-derivative-4q Indol-thioxotetrahydropyrimidine-Cpd7 Isosorbide-2-benzylcarbamate-5-benzoate Isosorbide-2-benzylcarbamate-5-benzyl-ether Isosorbide-2-benzylcarbamate-5-salicylate Isosorbide-2-butylcarbamate-5-lipoic-acid-ester JU5 JUB MT-031 MTDL-cpd36-diphenylacetamide MTDL-cpd51-diphenylacetamide MTR-1 MTR-3 Malachite-Green Meperidine Methyldifazine Mivacurium N-10-Phenothiazine-1-Naphtyl-carbamate N-alkyl-quinuclidine-cpd14 N-benzylpiperidine-carbazol-9c N-demethylhuperzinine NMDA-BCHE-4a NMDA-BCHE-C-2h Naphthalen-1-yloxymethyl-triazol-thiazol-cpd35a Naphthalen-2-yloxymethyl-triazol-thiazol-cpd37a P11149 PE154 PGN33 Phenyl-phenylpyridin-oxadiazol-cpd5a Piperidine-4-carboxamide-alkyl-tacrine-cpd16 Propargyl-Tacrine-15 Propidium Pyranone-carbamate-cpd7p Pyridostigmine Quinone-polyamine-NSAID-4 Rivastigmine-Donepezil-COR783 Russian-VX S06-1011 S11-1014 S16-1029 S17-1001 S21-1001 SB-1436 SB-1448 ST052207 STL118972 Salicylamide-8-Tacrine Salicylic-donepezil-rivastigmine-5a Sarin Soman Tacrine Tacrine-Benzofuran Tacrine-Sibiriline-Cpd7 Tacrine-methylanacardate-cpd5 Tacrine-pentylmethylene-tolylsulfonamide Tacrine-selegiline-7d Tacrine-selegiline-8g Terbutaline-monocarbamate Tetracyclic-carbamate-UW-MD-95 Tetracyclic-carbamate-cp8 Tetracyclic-carbamate-ferulicacid-4a Tetracyclic-carbamate-melatonine-3c Tetracyclic-carbamate-photoswitch-azo Thioflavin-T Toluidine-Blue Tosyl-L-lysine-chloromethyl-ketone Tosyl-Octyl-2-aminobenzo-thiazole-6-carboxylate-cpd6k Tryptophan-tetrahydroisoquinoline-Cpd7g VX VX-Biotin Xanthostigmine ZINC20166201-cpd8 hAChE-IN-6 hBChE-IN-1-Cpd4 tacrine-isatin-Cpd7d

Database

Sequence

Peptide

EDDIIIATKN GKVRGMNLTV FGGTVTAFLG IPYAQPPLGR LRFKKPQSLT KWSDIWNATK YANSCCQNID QSFPGFHGSE MWNPNTDLSE DCLYLNVWIP APKPKNATVL IWIYGGGFQT GTSSLHVYDG KFLARVERVI VVSMNYRVGA LGFLALPGNP EAPGNMGLFD QQLALQWVQK NIAAFGGNPK SVTLFGESAG AASVSLHLLS PGSHSLFTRA ILQSGSFNAP WAVTSLYEAR NRTLNLAKLT GCSRENETEI IKCLRNKDPQ EILLNEAFVV PYGTPLSVNF GPTVDGDFLT DMPDILLELG QFKKTQILVG VNKDEGTAFL VYGAPGFSKD NNSIITRKEF QEGLKIFFPG VSEFGKESIL FHYTDWVDDQ RPENYREALG DVVGDYNFIC PALEFTKKFS EWGNNAFFYY FEHRSSKLPW PEWMGVMHGY EIEFVFGLPL ERRDNYTKAE EILSRSIVKR WANFAKYGNP NETQNNSTSW PVFKSTEQKY LTLNTESTRI MTKLRAQQCR FWTSFFPKVL EMTGNIDEAE WEWKAGFHRW NNYMMDWKNQ FNDYTSKKES CVGL

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Gene_locus related to this paper: human-ACHE , human-BCHE

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Gene_locus related to this paper: human-BCHE

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Title : Enantioseparation, in vitro testing, and structural characterization of triple-binding reactivators of organophosphate-inhibited cholinesterases - Marakovic_2020_Biochem.J_477_2771
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Gene_locus related to this paper: human-BCHE

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Gene_locus related to this paper: human-BCHE

Title : N-alkylpiperidine carbamates as potential anti-Alzheimer's agents - Kosak_2020_Eur.J.Med.Chem_197_112282
Author(s) : Kosak U , Strasek N , Knez N , Jukic M , Zakelj S , Zahirovic A , Pislar A , Brazzolotto X , Nachon F , Kos J , Gobec S , Knez D
Ref : Eur Journal of Medicinal Chemistry , 197 :112282 , 2020
Abstract :
PubMedSearch : Kosak_2020_Eur.J.Med.Chem_197_112282
PubMedID: 32380361
Gene_locus related to this paper: human-BCHE

Title : Development of potent reversible selective inhibitors of butyrylcholinesterase as fluorescent probes - Pajk_2020_J.Enzyme.Inhib.Med.Chem_35_498
Author(s) : Pajk S , Knez D , Kosak U , Zorovic M , Brazzolotto X , Coquelle N , Nachon F , Colletier JP , Zivin M , Stojan J , Gobec S
Ref : J Enzyme Inhib Med Chem , 35 :498 , 2020
Abstract :
PubMedSearch : Pajk_2020_J.Enzyme.Inhib.Med.Chem_35_498
PubMedID: 31914836
Gene_locus related to this paper: human-BCHE

Title : Tryptophan-derived butyrylcholinesterase inhibitors as promising leads against Alzheimer's disease - Meden_2019_Chem.Commun.(Camb)_55_3765
Author(s) : Meden A , Knez D , Jukic M , Brazzolotto X , Grsic M , Pislar A , Zahirovic A , Kos J , Nachon F , Svete J , Gobec S , Groselj U
Ref : Chem Commun (Camb) , 55 :3765 , 2019
Abstract :
PubMedSearch : Meden_2019_Chem.Commun.(Camb)_55_3765
PubMedID: 30864579
Gene_locus related to this paper: human-BCHE

Title : Rivastigmine and metabolite analogues with putative Alzheimer's disease-modifying properties in a Caenorhabditis elegans model. - Dighe_2019_Commun.Chem_2_35
Author(s) : Dighe SN , De la Mora E , Chan S , Kantham S , McColl G , Miles JA , Veliyath SK , Sreenivas BY , Nassar ZD , Silman I , Sussman JL , Weik M , McGeary RP , Parat MO , Brazzolotto X , Ross BP
Ref : Communications chemistry , 2 :35 , 2019
Abstract :
PubMedSearch : Dighe_2019_Commun.Chem_2_35
PubMedID:
Gene_locus related to this paper: human-BCHE , torca-ACHE

Title : Cryo-EM structure of the native butyrylcholinesterase tetramer reveals a dimer of dimers stabilized by a superhelical assembly - Leung_2018_Proc.Natl.Acad.Sci.U.S.A_115_13270
Author(s) : Leung MR , van Bezouwen LS , Schopfer LM , Sussman JL , Silman I , Lockridge O , Zeev-Ben-Mordehai T
Ref : Proc Natl Acad Sci U S A , 115 :13270 , 2018
Abstract :
PubMedSearch : Leung_2018_Proc.Natl.Acad.Sci.U.S.A_115_13270
PubMedID: 30538207
Gene_locus related to this paper: human-BCHE

Title : Multi-target-directed ligands for treating Alzheimer's disease: Butyrylcholinesterase inhibitors displaying antioxidant and neuroprotective activities - Knez_2018_Eur.J.Med.Chem_156_598
Author(s) : Knez D , Coquelle N , Pislar A , Zakelj S , Jukic M , Sova M , Mravljak J , Nachon F , Brazzolotto X , Kos J , Colletier JP , Gobec S
Ref : Eur Journal of Medicinal Chemistry , 156 :598 , 2018
Abstract :
PubMedSearch : Knez_2018_Eur.J.Med.Chem_156_598
PubMedID: 30031971
Gene_locus related to this paper: human-BCHE

Title : The Magic of Crystal Structure-Based Inhibitor Optimization: Development of a Butyrylcholinesterase Inhibitor with Picomolar Affinity and in Vivo Activity - Kosak_2018_J.Med.Chem_61_119
Author(s) : Kosak U , Brus B , Knez D , Zakelj S , Trontelj J , Pislar A , Sink R , Jukic M , Zivin M , Podkowa A , Nachon F , Brazzolotto X , Stojan J , Kos J , Coquelle N , Salat K , Colletier JP , Gobec S
Ref : Journal of Medicinal Chemistry , 61 :119 , 2018
Abstract :
PubMedSearch : Kosak_2018_J.Med.Chem_61_119
PubMedID: 29227101
Gene_locus related to this paper: human-BCHE

Title : Comparison of the Binding of Reversible Inhibitors to Human Butyrylcholinesterase and Acetylcholinesterase: A Crystallographic, Kinetic and Calorimetric Study - Rosenberry_2017_Molecules_22_
Author(s) : Rosenberry TL , Brazzolotto X , Macdonald IR , Wandhammer M , Trovaslet-Leroy M , Darvesh S , Nachon F
Ref : Molecules , 22 : , 2017
Abstract :
PubMedSearch : Rosenberry_2017_Molecules_22_
PubMedID: 29186056
Gene_locus related to this paper: human-BCHE

Title : N-Propargylpiperidines with naphthalene-2-carboxamide or naphthalene-2-sulfonamide moieties: Potential multifunctional anti-Alzheimer's agents - Kosak_2017_Bioorg.Med.Chem_25_633
Author(s) : Kosak U , Knez D , Coquelle N , Brus B , Pislar A , Nachon F , Brazzolotto X , Kos J , Colletier JP , Gobec S
Ref : Bioorganic & Medicinal Chemistry , 25 :633 , 2017
Abstract :
PubMedSearch : Kosak_2017_Bioorg.Med.Chem_25_633
PubMedID: 27908752
Gene_locus related to this paper: human-BCHE

Title : Bacterial Expression of Human Butyrylcholinesterase as a Tool for Nerve Agent Bioscavengers Development - Brazzolotto_2017_Molecules_22_
Author(s) : Brazzolotto X , Igert A , Guillon V , Santoni G , Nachon F
Ref : Molecules , 22 : , 2017
Abstract :
PubMedSearch : Brazzolotto_2017_Molecules_22_
PubMedID: 29077024
Gene_locus related to this paper: human-BCHE

Title : The C5 Variant of the Butyrylcholinesterase Tetramer Includes a Noncovalently Bound 60 kDa Lamellipodin Fragment - Schopfer_2017_Molecules_22_
Author(s) : Schopfer LM , Delacour H , Masson P , Leroy J , Krejci E , Lockridge O
Ref : Molecules , 22 : , 2017
Abstract :
PubMedSearch : Schopfer_2017_Molecules_22_
PubMedID: 28661448
Gene_locus related to this paper: human-BCHE

Title : Development of an in-vivo active reversible butyrylcholinesterase inhibitor - Kosak_2016_Sci.Rep_6_39495
Author(s) : Kosak U , Brus B , Knez D , Sink R , Zakelj S , Trontelj J , Pislar A , Slenc J , Gobec M , Zivin M , Tratnjek L , Perse M , Salat K , Podkowa A , Filipek B , Nachon F , Brazzolotto X , Wieckowska A , Malawska B , Stojan J , Rascan IM , Kos J , Coquelle N , Colletier JP , Gobec S
Ref : Sci Rep , 6 :39495 , 2016
Abstract :
PubMedSearch : Kosak_2016_Sci.Rep_6_39495
PubMedID: 28000737
Gene_locus related to this paper: human-BCHE

Title : Discovery and Structure-Activity Relationships of a Highly Selective Butyrylcholinesterase Inhibitor by Structure-Based Virtual Screening - Dighe_2016_J.Med.Chem_59_7683
Author(s) : Dighe SN , Deora GS , De la Mora E , Nachon F , Chan S , Parat MO , Brazzolotto X , Ross BP
Ref : Journal of Medicinal Chemistry , 59 :7683 , 2016
Abstract :
PubMedSearch : Dighe_2016_J.Med.Chem_59_7683
PubMedID: 27405689
Gene_locus related to this paper: human-BCHE

Title : Structure-based development of nitroxoline derivatives as potential multifunctional anti-Alzheimer agents - Knez_2015_Bioorg.Med.Chem_23_4442
Author(s) : Knez D , Brus B , Coquelle N , Sosic I , Sink R , Brazzolotto X , Mravljak J , Colletier JP , Gobec S
Ref : Bioorganic & Medicinal Chemistry , 23 :4442 , 2015
Abstract :
PubMedSearch : Knez_2015_Bioorg.Med.Chem_23_4442
PubMedID: 26116179
Gene_locus related to this paper: human-BCHE

Title : Kinetic characterization of a cocaine hydrolase engineered from mouse butyrylcholinesterase - Chen_2015_Biochem.J_466_243
Author(s) : Chen X , Huang X , Geng L , Xue L , Hou S , Zheng X , Brimijoin S , Zheng F , Zhan CG
Ref : Biochemical Journal , 466 :243 , 2015
Abstract :
PubMedSearch : Chen_2015_Biochem.J_466_243
PubMedID: 25486543
Gene_locus related to this paper: human-BCHE

Title : Discovery, biological evaluation, and crystal structure of a novel nanomolar selective butyrylcholinesterase inhibitor - Brus_2014_J.Med.Chem_57_8167
Author(s) : Brus B , Kosak U , Turk S , Pislar A , Coquelle N , Kos J , Stojan J , Colletier JP , Gobec S
Ref : Journal of Medicinal Chemistry , 57 :8167 , 2014
Abstract :
PubMedSearch : Brus_2014_J.Med.Chem_57_8167
PubMedID: 25226236
Gene_locus related to this paper: human-BCHE

Title : A highly efficient cocaine-detoxifying enzyme obtained by computational design - Zheng_2014_Nat.Commun_5_3457
Author(s) : Zheng F , Xue L , Hou S , Liu J , Zhan M , Yang W , Zhan CG
Ref : Nat Commun , 5 :3457 , 2014
Abstract :
PubMedSearch : Zheng_2014_Nat.Commun_5_3457
PubMedID: 24643289
Gene_locus related to this paper: human-BCHE

Title : Amino-acid mutations to extend the biological half-life of a therapeutically valuable mutant of human butyrylcholinesterase - Fang_2014_Chem.Biol.Interact_214C_18
Author(s) : Fang L , Hou S , Xue L , Zheng F , Zhan CG
Ref : Chemico-Biological Interactions , 214C :18 , 2014
Abstract :
PubMedSearch : Fang_2014_Chem.Biol.Interact_214C_18
PubMedID: 24582612
Gene_locus related to this paper: human-BCHE

Title : Crystal structures of human cholinesterases in complex with huprine W and tacrine: elements of specificity for anti-Alzheimer's drugs targeting acetyl- and butyryl-cholinesterase - Nachon_2013_Biochem.J_453_393
Author(s) : Nachon F , Carletti E , Ronco C , Trovaslet M , Nicolet Y , Jean L , Renard PY
Ref : Biochemical Journal , 453 :393 , 2013
Abstract :
PubMedSearch : Nachon_2013_Biochem.J_453_393
PubMedID: 23679855
Gene_locus related to this paper: human-ACHE , human-BCHE

Title : Inhibition pathways of the potent organophosphate CBDP with cholinesterases revealed by X-ray crystallographic snapshots and mass spectrometry - Carletti_2013_Chem.Res.Toxicol_26_280
Author(s) : Carletti E , Colletier JP , Schopfer LM , Santoni G , Masson P , Lockridge O , Nachon F , Weik M
Ref : Chemical Research in Toxicology , 26 :280 , 2013
Abstract :
PubMedSearch : Carletti_2013_Chem.Res.Toxicol_26_280
PubMedID: 23339663
Gene_locus related to this paper: human-BCHE , mouse-ACHE

Title : A step toward the reactivation of aged cholinesterases - Crystal structure of ligands binding to aged human butyrylcholinesterase - Wandhammer_2013_Chem.Biol.Interact_203_19
Author(s) : Wandhammer M , De Koning MC , van Grol M , Loiodice M , Saurel L , Noort D , Goeldner M , Nachon F
Ref : Chemico-Biological Interactions , 203 :19 , 2013
Abstract :
PubMedSearch : Wandhammer_2013_Chem.Biol.Interact_203_19
PubMedID: 22922115
Gene_locus related to this paper: human-BCHE

Title : Human butyrylcholinesterase produced in insect cells: huprine-based affinity purification and crystal structure - Brazzolotto_2012_Febs.J_279_2905
Author(s) : Brazzolotto X , Wandhammer M , Ronco C , Trovaslet M , Jean L , Lockridge O , Renard PY , Nachon F
Ref : Febs J , 279 :2905 , 2012
Abstract :
PubMedSearch : Brazzolotto_2012_Febs.J_279_2905
PubMedID: 22726956
Gene_locus related to this paper: human-BCHE

Title : X-ray crystallographic snapshots of reaction intermediates in the G117H mutant of human butyrylcholinesterase, a nerve agent target engineered into a catalytic bioscavenger - Nachon_2011_Biochem.J_434_73
Author(s) : Nachon F , Carletti E , Wandhammer M , Nicolet Y , Schopfer LM , Masson P , Lockridge O
Ref : Biochemical Journal , 434 :73 , 2011
Abstract :
PubMedSearch : Nachon_2011_Biochem.J_434_73
PubMedID: 21091433
Gene_locus related to this paper: human-BCHE

Title : Reaction of cresyl saligenin phosphate, the organophosphorus agent implicated in aerotoxic syndrome, with human cholinesterases: mechanistic studies employing kinetics, mass spectrometry, and X-ray structure analysis - Carletti_2011_Chem.Res.Toxicol_24_797
Author(s) : Carletti E , Schopfer LM , Colletier JP , Froment MT , Nachon F , Weik M , Lockridge O , Masson P
Ref : Chemical Research in Toxicology , 24 :797 , 2011
Abstract :
PubMedSearch : Carletti_2011_Chem.Res.Toxicol_24_797
PubMedID: 21438623
Gene_locus related to this paper: human-BCHE

Title : Structural study of the complex stereoselectivity of human butyrylcholinesterase for the neurotoxic V-agents - Wandhammer_2011_J.Biol.Chem_286_16783
Author(s) : Wandhammer M , Carletti E , van der Schans M , Gillon E , Nicolet Y , Masson P , Goeldner M , Noort D , Nachon F
Ref : Journal of Biological Chemistry , 286 :16783 , 2011
Abstract :
PubMedSearch : Wandhammer_2011_J.Biol.Chem_286_16783
PubMedID: 21454498
Gene_locus related to this paper: human-BCHE

Title : Cocrystallization studies of full-length recombinant butyrylcholinesterase (BChE) with cocaine - Asojo_2011_Acta.Crystallogr.Sect.F.Struct.Biol.Cryst.Commun_67_434
Author(s) : Asojo OA , Ngamelue MN , Homma K , Lockridge O
Ref : Acta Crystallographica Sect F Struct Biol Cryst Commun , 67 :434 , 2011
Abstract :
PubMedSearch : Asojo_2011_Acta.Crystallogr.Sect.F.Struct.Biol.Cryst.Commun_67_434
PubMedID: 21505234
Gene_locus related to this paper: human-BCHE

Title : Structure-activity analysis of aging and reactivation of human butyrylcholinesterase inhibited by analogues of tabun. - Carletti_2009_Biochem.J_421_97
Author(s) : Carletti E , Aurbek N , Gillon E , Loiodice M , Nicolet Y , Fontecilla-Camps JC , Masson P , Thiermann H , Nachon F , Worek F
Ref : Biochemical Journal , 421 :97 , 2009
Abstract :
PubMedSearch : Carletti_2009_Biochem.J_421_97
PubMedID: 19368529
Gene_locus related to this paper: human-BCHE

Title : Aging of cholinesterases phosphylated by tabun proceeds through O-dealkylation - Carletti_2008_J.Am.Chem.Soc_130_16011
Author(s) : Carletti E , Li H , Li B , Ekstrom F , Nicolet Y , Loiodice M , Gillon E , Froment MT , Lockridge O , Schopfer LM , Masson P , Nachon F
Ref : Journal of the American Chemical Society , 130 :16011 , 2008
Abstract :
PubMedSearch : Carletti_2008_J.Am.Chem.Soc_130_16011
PubMedID: 18975951
Gene_locus related to this paper: human-BCHE , mouse-ACHE

Title : Crystallization and X-ray structure of full-length recombinant human butyrylcholinesterase - Ngamelue_2007_Acta.Crystallogr.Sect.F.Struct.Biol.Cryst.Commun_63_723
Author(s) : Ngamelue MN , Homma K , Lockridge O , Asojo OA
Ref : Acta Crystallographica Sect F Struct Biol Cryst Commun , 63 :723 , 2007
Abstract :
PubMedSearch : Ngamelue_2007_Acta.Crystallogr.Sect.F.Struct.Biol.Cryst.Commun_63_723
PubMedID: 17768338
Gene_locus related to this paper: human-BCHE

Title : Mechanisms of cholinesterase inhibition by inorganic mercury - Frasco_2007_FEBS.J_274_1849
Author(s) : Frasco MF , Colletier JP , Weik M , Carvalho F , Guilhermino L , Stojan J , Fournier D
Ref : Febs J , 274 :1849 , 2007
Abstract :
PubMedSearch : Frasco_2007_FEBS.J_274_1849
PubMedID: 17355286
Gene_locus related to this paper: human-BCHE

Title : The DNA sequence, annotation and analysis of human chromosome 3 - Muzny_2006_Nature_440_1194
Author(s) : Muzny DM , Scherer SE , Kaul R , Wang J , Yu J , Sudbrak R , Buhay CJ , Chen R , Cree A , Ding Y , Dugan-Rocha S , Gill R , Gunaratne P , Harris RA , Hawes AC , Hernandez J , Hodgson AV , Hume J , Jackson A , Khan ZM , Kovar-Smith C , Lewis LR , Lozado RJ , Metzker ML , Milosavljevic A , Miner GR , Morgan MB , Nazareth LV , Scott G , Sodergren E , Song XZ , Steffen D , Wei S , Wheeler DA , Wright MW , Worley KC , Yuan Y , Zhang Z , Adams CQ , Ansari-Lari MA , Ayele M , Brown MJ , Chen G , Chen Z , Clendenning J , Clerc-Blankenburg KP , Davis C , Delgado O , Dinh HH , Dong W , Draper H , Ernst S , Fu G , Gonzalez-Garay ML , Garcia DK , Gillett W , Gu J , Hao B , Haugen E , Havlak P , He X , Hennig S , Hu S , Huang W , Jackson LR , Jacob LS , Kelly SH , Kube M , Levy R , Li Z , Liu B , Liu J , Liu W , Lu J , Maheshwari M , Nguyen BV , Okwuonu GO , Palmeiri A , Pasternak S , Perez LM , Phelps KA , Plopper FJ , Qiang B , Raymond C , Rodriguez R , Saenphimmachak C , Santibanez J , Shen H , Shen Y , Subramanian S , Tabor PE , Verduzco D , Waldron L , Wang Q , Williams GA , Wong GK , Yao Z , Zhang J , Zhang X , Zhao G , Zhou J , Zhou Y , Nelson D , Lehrach H , Reinhardt R , Naylor SL , Yang H , Olson M , Weinstock G , Gibbs RA
Ref : Nature , 440 :1194 , 2006
Abstract :
PubMedSearch : Muzny_2006_Nature_440_1194
PubMedID: 16641997
Gene_locus related to this paper: human-AADAC , human-AADACL2 , human-ABHD5 , human-ABHD6 , human-ABHD10 , human-ABHD14A , human-APEH , human-BCHE , human-CIB , human-LIPH , human-MGLL , human-NLGN1 , human-PLA1A

Title : Naturally occurring mutation Leu307Pro of human butyrylcholinesterase in the Vysya community of India - Manoharan_2006_Pharmacogenet.Genomics_16_461
Author(s) : Manoharan I , Wieseler S , Layer PG , Lockridge O , Boopathy R
Ref : Pharmacogenet Genomics , 16 :461 , 2006
Abstract :
PubMedSearch : Manoharan_2006_Pharmacogenet.Genomics_16_461
PubMedID: 16788378
Gene_locus related to this paper: human-BCHE

Title : Role of water in aging of human butyrylcholinesterase inhibited by echothiophate: the crystal structure suggests two alternative mechanisms of aging - Nachon_2005_Biochemistry_44_1154
Author(s) : Nachon F , Asojo OA , Borgstahl GE , Masson P , Lockridge O
Ref : Biochemistry , 44 :1154 , 2005
Abstract :
PubMedSearch : Nachon_2005_Biochemistry_44_1154
PubMedID: 15667209
Gene_locus related to this paper: human-BCHE

Title : Crystal structure of human butyrylcholinesterase and of its complexes with substrate and products - Nicolet_2003_J.Biol.Chem_278_41141
Author(s) : Nicolet Y , Lockridge O , Masson P , Fontecilla-Camps JC , Nachon F
Ref : Journal of Biological Chemistry , 278 :41141 , 2003
Abstract :
PubMedSearch : Nicolet_2003_J.Biol.Chem_278_41141
PubMedID: 12869558
Gene_locus related to this paper: human-BCHE

Title : Cocaine metabolism accelerated by a re-engineered human butyrylcholinesterase - Sun_2002_J.Pharmacol.Exp.Ther_302_710
Author(s) : Sun H , Shen ML , Pang YP , Lockridge O , Brimijoin S
Ref : Journal of Pharmacology & Experimental Therapeutics , 302 :710 , 2002
Abstract :
PubMedSearch : Sun_2002_J.Pharmacol.Exp.Ther_302_710
PubMedID: 12130735
Gene_locus related to this paper: human-BCHE

Title : Re-engineering butyrylcholinesterase as a cocaine hydrolase - Sun_2002_Mol.Pharmacol_62_220
Author(s) : Sun H , Pang YP , Lockridge O , Brimijoin S
Ref : Molecular Pharmacology , 62 :220 , 2002
Abstract :
PubMedSearch : Sun_2002_Mol.Pharmacol_62_220
PubMedID: 12130672
Gene_locus related to this paper: human-BCHE

Title : Effects of mutations of active site residues and amino acids interacting with the Omega loop on substrate activation of butyrylcholinesterase - Masson_2001_Biochim.Biophys.Acta_1544_166
Author(s) : Masson P , Xie W , Froment MT , Lockridge O
Ref : Biochimica & Biophysica Acta , 1544 :166 , 2001
Abstract :
PubMedSearch : Masson_2001_Biochim.Biophys.Acta_1544_166
PubMedID: 11341926
Gene_locus related to this paper: human-BCHE

Title : The sequence of the human genome - Venter_2001_Science_291_1304
Author(s) : Venter JC , Adams MD , Myers EW , Li PW , Mural RJ , Sutton GG , Smith HO , Yandell M , Evans CA , Holt RA , Gocayne JD , Amanatides P , Ballew RM , Huson DH , Wortman JR , Zhang Q , Kodira CD , Zheng XH , Chen L , Skupski M , Subramanian G , Thomas PD , Zhang J , Gabor Miklos GL , Nelson C , Broder S , Clark AG , Nadeau J , McKusick VA , Zinder N , Levine AJ , Roberts RJ , Simon M , Slayman C , Hunkapiller M , Bolanos R , Delcher A , Dew I , Fasulo D , Flanigan M , Florea L , Halpern A , Hannenhalli S , Kravitz S , Levy S , Mobarry C , Reinert K , Remington K , Abu-Threideh J , Beasley E , Biddick K , Bonazzi V , Brandon R , Cargill M , Chandramouliswaran I , Charlab R , Chaturvedi K , Deng Z , Di Francesco V , Dunn P , Eilbeck K , Evangelista C , Gabrielian AE , Gan W , Ge W , Gong F , Gu Z , Guan P , Heiman TJ , Higgins ME , Ji RR , Ke Z , Ketchum KA , Lai Z , Lei Y , Li Z , Li J , Liang Y , Lin X , Lu F , Merkulov GV , Milshina N , Moore HM , Naik AK , Narayan VA , Neelam B , Nusskern D , Rusch DB , Salzberg S , Shao W , Shue B , Sun J , Wang Z , Wang A , Wang X , Wang J , Wei M , Wides R , Xiao C , Yan C , Yao A , Ye J , Zhan M , Zhang W , Zhang H , Zhao Q , Zheng L , Zhong F , Zhong W , Zhu S , Zhao S , Gilbert D , Baumhueter S , Spier G , Carter C , Cravchik A , Woodage T , Ali F , An H , Awe A , Baldwin D , Baden H , Barnstead M , Barrow I , Beeson K , Busam D , Carver A , Center A , Cheng ML , Curry L , Danaher S , Davenport L , Desilets R , Dietz S , Dodson K , Doup L , Ferriera S , Garg N , Gluecksmann A , Hart B , Haynes J , Haynes C , Heiner C , Hladun S , Hostin D , Houck J , Howland T , Ibegwam C , Johnson J , Kalush F , Kline L , Koduru S , Love A , Mann F , May D , McCawley S , McIntosh T , McMullen I , Moy M , Moy L , Murphy B , Nelson K , Pfannkoch C , Pratts E , Puri V , Qureshi H , Reardon M , Rodriguez R , Rogers YH , Romblad D , Ruhfel B , Scott R , Sitter C , Smallwood M , Stewart E , Strong R , Suh E , Thomas R , Tint NN , Tse S , Vech C , Wang G , Wetter J , Williams S , Williams M , Windsor S , Winn-Deen E , Wolfe K , Zaveri J , Zaveri K , Abril JF , Guigo R , Campbell MJ , Sjolander KV , Karlak B , Kejariwal A , Mi H , Lazareva B , Hatton T , Narechania A , Diemer K , Muruganujan A , Guo N , Sato S , Bafna V , Istrail S , Lippert R , Schwartz R , Walenz B , Yooseph S , Allen D , Basu A , Baxendale J , Blick L , Caminha M , Carnes-Stine J , Caulk P , Chiang YH , Coyne M , Dahlke C , Mays A , Dombroski M , Donnelly M , Ely D , Esparham S , Fosler C , Gire H , Glanowski S , Glasser K , Glodek A , Gorokhov M , Graham K , Gropman B , Harris M , Heil J , Henderson S , Hoover J , Jennings D , Jordan C , Jordan J , Kasha J , Kagan L , Kraft C , Levitsky A , Lewis M , Liu X , Lopez J , Ma D , Majoros W , McDaniel J , Murphy S , Newman M , Nguyen T , Nguyen N , Nodell M , Pan S , Peck J , Peterson M , Rowe W , Sanders R , Scott J , Simpson M , Smith T , Sprague A , Stockwell T , Turner R , Venter E , Wang M , Wen M , Wu D , Wu M , Xia A , Zandieh A , Zhu X
Ref : Science , 291 :1304 , 2001
Abstract :
PubMedSearch : Venter_2001_Science_291_1304
PubMedID: 11181995
Gene_locus related to this paper: human-AADAC , human-ABHD1 , human-ABHD10 , human-ABHD11 , human-ACHE , human-BCHE , human-LDAH , human-ABHD18 , human-CMBL , human-ABHD17A , human-KANSL3 , human-LIPA , human-LYPLAL1 , human-NDRG2 , human-NLGN3 , human-NLGN4X , human-NLGN4Y , human-PAFAH2 , human-PREPL , human-RBBP9 , human-SPG21

Title : Butyrylcholinesterase genes in individuals with abnormal inhibition numbers and with trace activity: one common mutation and two novel silent genes - Dey_1998_Ann.Clin.Biochem_35_302
Author(s) : Dey DC , Maekawa M , Sudo K , Kanno T
Ref : Annals of Clinical Biochemistry , 35 :302 , 1998
Abstract :
PubMedSearch : Dey_1998_Ann.Clin.Biochem_35_302
PubMedID: 9547905
Gene_locus related to this paper: human-BCHE

Title : Organophosphorus acid anhydride hydrolase activity in human butyrylcholinesterase: synergy results in a somanase - Millard_1998_Biochemistry_37_237
Author(s) : Millard CB , Lockridge O , Broomfield CA
Ref : Biochemistry , 37 :237 , 1998
Abstract :
PubMedSearch : Millard_1998_Biochemistry_37_237
PubMedID: 9425044
Gene_locus related to this paper: human-BCHE

Title : Human butyrylcholinesterase L330I mutation belongs to a fluoride-resistant gene, by expression in human fetal kidney cells - Sudo_1997_Biochem.Biophys.Res.Commun_240_372
Author(s) : Sudo K , Maekawa M , Akizuki S , Magara T , Ogasawara H , Tanaka T
Ref : Biochemical & Biophysical Research Communications , 240 :372 , 1997
Abstract :
PubMedSearch : Sudo_1997_Biochem.Biophys.Res.Commun_240_372
PubMedID: 9388484
Gene_locus related to this paper: human-BCHE

Title : Overlapping drug interaction sites of human butyrylcholinesterase dissected by site-directed mutagenesis - Loewenstein-Lichtenstein_1996_Mol.Pharmacol_50_1423
Author(s) : Loewenstein-Lichtenstein Y , Glick D , Gluzman N , Sternfeld M , Zakut H , Soreq H
Ref : Molecular Pharmacology , 50 :1423 , 1996
Abstract :
PubMedSearch : Loewenstein-Lichtenstein_1996_Mol.Pharmacol_50_1423
PubMedID: 8967962
Gene_locus related to this paper: human-BCHE

Title : Prolonged response to succinylcholine: a new variant of plasma cholinesterase that is identified as normal by traditional phenotyping methods -
Author(s) : Greenberg CP , Primo-Parmo SL , Pantuck EJ , La Du BN
Ref : Anesthesia & Analgesia , 81 :419 , 1995
PubMedID: 7618741
Gene_locus related to this paper: human-BCHE

Title : Dissection of the human acetylcholinesterase active center determinants of substrate specificity. Identification of residues constituting the anionic site, the hydrophobic site, and the acyl pocket - Ordentlich_1993_J.Biol.Chem_268_17083
Author(s) : Ordentlich A , Barak D , Kronman C , Flashner Y , Leitner M , Segall Y , Ariel N , Cohen S , Velan B , Shafferman A
Ref : Journal of Biological Chemistry , 268 :17083 , 1993
Abstract :
PubMedSearch : Ordentlich_1993_J.Biol.Chem_268_17083
PubMedID: 8349597
Gene_locus related to this paper: human-ACHE , human-BCHE

Title : Genetic variants of human serum cholinesterase influence metabolism of the muscle relaxant succinylcholine. - Lockridge_1990_Pharmacol.Ther_47_35
Author(s) : Lockridge O
Ref : Pharmacol Ther , 47 :35 , 1990
Abstract :
PubMedSearch : Lockridge_1990_Pharmacol.Ther_47_35
PubMedID: 2195556
Gene_locus related to this paper: human-BCHE

Title : Aspartate-70 to glycine substitution confers resistance to naturally occurring and synthetic anionic-site ligands on in-ovo produced human butyrylcholinesterase - Neville_1990_J.Neurosci.Res_27_452
Author(s) : Neville LF , Gnatt A , Loewenstein Y , Soreq H
Ref : Journal of Neuroscience Research , 27 :452 , 1990
Abstract :
PubMedSearch : Neville_1990_J.Neurosci.Res_27_452
PubMedID: 2079709
Gene_locus related to this paper: human-BCHE

Title : Structure of human serum cholinesterase. -
Author(s) : Lockridge O
Ref : Bioessays , 9 :125 , 1988
PubMedID: 3067729
Gene_locus related to this paper: human-BCHE

Title : Brain cDNA clone for human cholinesterase - McTiernan_1987_Proc.Natl.Acad.Sci.U.S.A_84_6682
Author(s) : McTiernan C , Adkins S , Chatonnet A , Vaughan TA , Bartels CF , Kott M , Rosenberry TL , La Du BN , Lockridge O
Ref : Proceedings of the National Academy of Sciences of the United States of America , 84 :6682 , 1987
Abstract :
PubMedSearch : McTiernan_1987_Proc.Natl.Acad.Sci.U.S.A_84_6682
PubMedID: 3477799
Gene_locus related to this paper: human-BCHE

Title : Isolation and characterization of full-length cDNA clones coding for cholinesterase from fetal human tissues - Prody_1987_Proc.Natl.Acad.Sci.U.S.A_84_3555
Author(s) : Prody CA , Zevin-Sonkin D , Gnatt A , Goldberg O , Soreq H
Ref : Proceedings of the National Academy of Sciences of the United States of America , 84 :3555 , 1987
Abstract :
PubMedSearch : Prody_1987_Proc.Natl.Acad.Sci.U.S.A_84_3555
PubMedID: 3035536
Gene_locus related to this paper: human-BCHE

Title : Complete amino acid sequence of human serum cholinesterase - Lockridge_1987_J.Biol.Chem_262_549
Author(s) : Lockridge O , Bartels CF , Vaughan TA , Wong CK , Norton SE , Johnson LL
Ref : Journal of Biological Chemistry , 262 :549 , 1987
Abstract :
PubMedSearch : Lockridge_1987_J.Biol.Chem_262_549
PubMedID: 3542989
Gene_locus related to this paper: human-BCHE