C580K_human-ACHE

General

Gene Locus : human-ACHE

Mode of mutation : Site directed mutagenesis

Disease :

Summary : Intracellular retention Biosynthesis,Intracellular retention Velan_1994_J.Biol.Chem_269_22719 Kronman_1995_5th.ChE.Meeting.Madras__293

AAA Change :

Allelic Variant :

Risk Factor :

Inhibitor :

Structure :

Disease by interaction :

Interact Gene Locus :

Xenobiotic sensitivity :

Modification : Intracellular retention

Torpedo_number : 572

Kinetic Parameter : No kinetic parameter

News : No news

Comment :
p.C580K Cys580Lys (p.C611K Cys611Lys in primary sequence with 31 amino-acids signal peptide) Biosynthesis,Intracellular retention

References (2)

Title : Signal-Mediated Cellular Retention and Subunit Assembly of Human Acetylcholinesterase -
Author(s) : Kronman C , Flashner Y , Shafferman A , Velan B
Ref : In Enzyme of the Cholinesterase Family - Proceedings of Fifth International Meeting on Cholinesterases , (Quinn, D.M., Balasubramanian, A.S., Doctor, B.P., Taylor, P., Eds) Plenum Publishing Corp. :293 , 1995
PubMedID:

Title : Reversal of signal-mediated cellular retention by subunit assembly of human acetylcholinesterase - Velan_1994_J.Biol.Chem_269_22719
Author(s) : Velan B , Kronman C , Flashner Y , Shafferman A
Ref : Journal of Biological Chemistry , 269 :22719 , 1994
PubMedID: 8077224