Gene Locus : drome-ACHE
Mode of mutation : Site directed mutagenesis
Disease :
Summary : Insecticide sensitivity Boublik_2002_Protein.Eng_15_43 || Binding of Triton X-100 studies no effect on Triton X-100 binding Marcel_2000_J.Biol.Chem_275_11603
AAA Change :
Allelic Variant :
Risk Factor :
Inhibitor :
Structure :
Disease by interaction :
Interact Gene Locus :
Xenobiotic sensitivity :
Modification : Insecticide sensitivity || Binding of Triton X-100 studies
Torpedo_number : 290
Kinetic Parameter : No kinetic parameter
News : No news
Comment :
Mutation F330L in mature protein. Numbering in Boublik et al. 2002 || p.Phe368leu || p.Phe368Leu
Title : Acetylcholinesterase engineering for detection of insecticide residues - Boublik_2002_Protein.Eng_15_43 |
Author(s) : Boublik Y , Saint-Aguet P , Lougarre A , Arnaud M , Villatte F , Estrada-Mondaca S , Fournier D |
Ref : Protein Engineering , 15 :43 , 2002 |
Abstract : |
PubMedSearch : Boublik_2002_Protein.Eng_15_43 |
PubMedID: 11842237 |
Title : Exploration of the Drosophila acetylcholinesterase substrate activation site using a reversible inhibitor (Triton X-100) and mutated enzymes - Marcel_2000_J.Biol.Chem_275_11603 |
Author(s) : Marcel V , Estrada-Mondaca S , Magne F , Stojan J , Klaebe A , Fournier D |
Ref : Journal of Biological Chemistry , 275 :11603 , 2000 |
Abstract : |
PubMedSearch : Marcel_2000_J.Biol.Chem_275_11603 |
PubMedID: 10766776 |
Title : Improved multianalyte detection of organophosphates and carbamates with disposable multielectrode biosensors using recombinant mutants of Drosophila acetylcholinesterase and artificial neural networks - Bachmann_2000_Biosens.Bioelectron_15_193 |
Author(s) : Bachmann TT , Leca B , Vilatte F , Marty JL , Fournier D , Schmid RD |
Ref : Biosensors & Bioelectronics , 15 :193 , 2000 |
Abstract : |
PubMedSearch : Bachmann_2000_Biosens.Bioelectron_15_193 |
PubMedID: 11286337 |