Stojan J

General

Full name : Stojan Jure

First name : Jure

Mail : Faculty of Medicine\; University of Ljubljana\; Vrazov trg 2\; SI-1000 Ljubljana

Zip Code :

City :

Country : Slovenia

Email : jurestojan@yahoo.com

Phone : +38615437649

Fax :

Website : \/\/ibk.mf.uni-lj.si\/people\/jure

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References (55)

Title : Disentangling the formation, mechanism, and evolvement of the covalent methanesulfonyl fluoride acetylcholinesterase adduct: Insights into an aged-like inactive complex susceptible to reactivation by a combination of nucleophiles - Stojan_2024_Protein.Sci_33_e4977
Author(s) : Stojan J , Pesaresi A , Meden A , Lamba D
Ref : Protein Science , 33 :e4977 , 2024
PubMedID: 38591646

Title : Substrate-dependent inactivation of recombinant paraoxonase 1 during catalytic dihydrocoumarin turnover and the protective properties of surfactants - Smerkolj_2023_Chem.Biol.Interact_14ChEPon_382_110563
Author(s) : Smerkolj J , Stojan J , Bavec A , Golicnik M
Ref : Chemico-Biological Interactions , 382 :110563 , 2023
PubMedID: 37286155

Title : 8-Hydroxyquinolylnitrones as multifunctional ligands for the therapy of neurodegenerative diseases - Knez_2023_Acta.Pharmaceutica.Sinica.B_13_2152
Author(s) : Knez D , Diez-Iriepa D , Chioua M , Gottinger A , Denic M , Chantegreil F , Nachon F , Brazzolotto X , Skrzypczak-Wiercioch A , Meden A , Pislar A , Kos J , Zakelj S , Stojan J , Salat K , Serrano J , Patricia Fernandez AP , Sanchez-Garcia A , Martinez-Murillo R , Binda C , Lopez-Munoz F , Gobec S , Marco-Contelle J
Ref : Acta Pharmaceutica Sinica B , 13 :2152 , 2023
PubMedID: 37250172
Gene_locus related to this paper: human-BCHE

Title : From tryptophan-based amides to tertiary amines: Optimization of a butyrylcholinesterase inhibitor series - Meden_2022_Eur.J.Med.Chem_230_114248
Author(s) : Meden A , Knez D , Brazzolotto X , Nachon F , Dias J , Svete J , Stojan J , Groselj U , Gobec S
Ref : Eur Journal of Medicinal Chemistry , 230 :114248 , 2022
PubMedID: 35299116
Gene_locus related to this paper: human-BCHE

Title : Development of potent reversible selective inhibitors of butyrylcholinesterase as fluorescent probes - Pajk_2020_J.Enzyme.Inhib.Med.Chem_35_498
Author(s) : Pajk S , Knez D , Kosak U , Zorovic M , Brazzolotto X , Coquelle N , Nachon F , Colletier JP , Zivin M , Stojan J , Gobec S
Ref : J Enzyme Inhib Med Chem , 35 :498 , 2020
PubMedID: 31914836
Gene_locus related to this paper: human-BCHE

Title : The mechanism and benefit of human butyrylcholinesterase activation by what would otherwise be inhibitors - Stojan_2019_Chem.Biol.Interact_13ChEPon_308_350
Author(s) : Stojan J
Ref : Chemico-Biological Interactions , 308 :350 , 2019
PubMedID: 31173753

Title : The Magic of Crystal Structure-Based Inhibitor Optimization: Development of a Butyrylcholinesterase Inhibitor with Picomolar Affinity and in Vivo Activity - Kosak_2018_J.Med.Chem_61_119
Author(s) : Kosak U , Brus B , Knez D , Zakelj S , Trontelj J , Pislar A , Sink R , Jukic M , Zivin M , Podkowa A , Nachon F , Brazzolotto X , Stojan J , Kos J , Coquelle N , Salat K , Colletier JP , Gobec S
Ref : Journal of Medicinal Chemistry , 61 :119 , 2018
PubMedID: 29227101
Gene_locus related to this paper: human-BCHE

Title : Rapid Mechanistic Evaluation and Parameter Estimation of Putative Inhibitors in a Single-Step Progress-Curve Analysis: The Case of Horse Butyrylcholinesterase - Stojan_2017_Molecules_22_
Author(s) : Stojan J
Ref : Molecules , 22 : , 2017
PubMedID: 28933751

Title : Conformational rigidity of cholinesterases allows for the prediction of combined effects in a particular double mutant - Stojan_2016_Chem.Biol.Interact_259_110
Author(s) : Stojan J
Ref : Chemico-Biological Interactions , 259 :110 , 2016
PubMedID: 27174135

Title : Development of an in-vivo active reversible butyrylcholinesterase inhibitor - Kosak_2016_Sci.Rep_6_39495
Author(s) : Kosak U , Brus B , Knez D , Sink R , Zakelj S , Trontelj J , Pislar A , Slenc J , Gobec M , Zivin M , Tratnjek L , Perse M , Salat K , Podkowa A , Filipek B , Nachon F , Brazzolotto X , Wieckowska A , Malawska B , Stojan J , Rascan IM , Kos J , Coquelle N , Colletier JP , Gobec S
Ref : Sci Rep , 6 :39495 , 2016
PubMedID: 28000737
Gene_locus related to this paper: human-BCHE

Title : Novel Tacrine-Benzofuran Hybrids as Potent Multitarget-Directed Ligands for the Treatment of Alzheimer's Disease: Design, Synthesis, Biological Evaluation, and X-ray Crystallography - Zha_2016_J.Med.Chem_59_114
Author(s) : Zha X , Lamba D , Zhang L , Lou Y , Xu C , Kang D , Chen L , Xu Y , De Simone A , Samez S , Pesaresi A , Stojan J , Lopez MG , Egea J , Andrisano V , Bartolini M
Ref : Journal of Medicinal Chemistry , 59 :114 , 2016
PubMedID: 26632651
Gene_locus related to this paper: torca-ACHE

Title : Discovery, biological evaluation, and crystal structure of a novel nanomolar selective butyrylcholinesterase inhibitor - Brus_2014_J.Med.Chem_57_8167
Author(s) : Brus B , Kosak U , Turk S , Pislar A , Coquelle N , Kos J , Stojan J , Colletier JP , Gobec S
Ref : Journal of Medicinal Chemistry , 57 :8167 , 2014
PubMedID: 25226236
Gene_locus related to this paper: human-BCHE

Title : Exploring the aryl esterase catalysis of paraoxonase-1 through solvent kinetic isotope effects and phosphonate-based isosteric analogues of the tetrahedral reaction intermediate - Bavec_2014_Biochimie_106_184
Author(s) : Bavec A , Knez D , Makovec T , Stojan J , Gobec S , Golicnik M
Ref : Biochimie , 106 :184 , 2014
PubMedID: 25180809

Title : The significance of low substrate concentration measurements for mechanistic interpretation in cholinesterases - Stojan_2013_Chem.Biol.Interact_203_44
Author(s) : Stojan J
Ref : Chemico-Biological Interactions , 203 :44 , 2013
PubMedID: 23279886

Title : Correction: Evidence for inhibition of cholinesterases in insect and mammalian nervous systems by the insect repellent deet - Corbel_2012_BMC.Biol_10_86
Author(s) : Corbel V , Stankiewicz M , Pennetier C , Fournier D , Stojan J , Girard E , Dimitrov M , Molgo J , Hougard JM , Lapied B
Ref : BMC Biol , 10 :86 , 2012
PubMedID: 23114027

Title : Kinetics of Torpedo californica acetylcholinesterase inhibition by bisnorcymserine and crystal structure of the complex with its leaving group - Bartolucci_2012_Biochem.J_444_269
Author(s) : Bartolucci C , Stojan J , Yu QS , Greig NH , Lamba D
Ref : Biochemical Journal , 444 :269 , 2012
PubMedID: 22390827
Gene_locus related to this paper: torma-ACHE

Title : Mechanism of stereoselective interaction between butyrylcholinesterase and ethopropazine enantiomers - Sinko_2011_Biochimie_93_1797
Author(s) : Sinko G , Kovarik Z , Reiner E , Simeon-Rudolf V , Stojan J
Ref : Biochimie , 93 :1797 , 2011
PubMedID: 21740955

Title : Non-productive binding of butyryl(thio)choline in the active site of vertebrate acetylcholinesterase - Stojan_2010_Chem.Biol.Interact_187_128
Author(s) : Stojan J
Ref : Chemico-Biological Interactions , 187 :128 , 2010
PubMedID: 20452336

Title : Evidence for inhibition of cholinesterases in insect and mammalian nervous systems by the insect repellent deet - Corbel_2009_BMC.Biol_7_47
Author(s) : Corbel V , Stankiewicz M , Pennetier C , Fournier D , Stojan J , Girard E , Dimitrov M , Molgo J , Hougard JM , Lapied B
Ref : BMC Biol , 7 :47 , 2009
PubMedID: 19656357

Title : Kinetic insight into the mechanism of cholinesterasterase inhibition by aflatoxin B1 to develop biosensors - Hansmann_2009_Biosens.Bioelectron_24_2119
Author(s) : Hansmann T , Sanson B , Stojan J , Weik M , Marty JL , Fournier D
Ref : Biosensors & Bioelectronics , 24 :2119 , 2009
PubMedID: 19109006

Title : Evidence for subdomain flexibility in Drosophila melanogaster acetylcholinesterase - Stojan_2008_Biochemistry_47_5599
Author(s) : Stojan J , Ladurantie C , Siadat OR , Paquereau L , Fournier D
Ref : Biochemistry , 47 :5599 , 2008
PubMedID: 18439026

Title : Insights into substrate and product traffic in the Drosophila melanogaster acetylcholinesterase active site gorge by enlarging a back channel - Nachon_2008_FEBS.J_275_2659
Author(s) : Nachon F , Stojan J , Fournier D
Ref : Febs J , 275 :2659 , 2008
PubMedID: 18422651

Title : Kinetic evaluation of multiple initial rate data by simultaneous analysis with two equations - Stojan_2008_Chem.Biol.Interact_175_242
Author(s) : Stojan J
Ref : Chemico-Biological Interactions , 175 :242 , 2008
PubMedID: 18579127

Title : Mechanisms of cholinesterase inhibition by inorganic mercury - Frasco_2007_FEBS.J_274_1849
Author(s) : Frasco MF , Colletier JP , Weik M , Carvalho F , Guilhermino L , Stojan J , Fournier D
Ref : Febs J , 274 :1849 , 2007
PubMedID: 17355286
Gene_locus related to this paper: human-BCHE

Title : Inhibition and protection of cholinesterases by methanol and ethanol - Fekonja_2007_J.Enzyme.Inhib.Med.Chem_22_407
Author(s) : Fekonja O , Zorec-Karlovsek M , El Kharbili M , Fournier D , Stojan J
Ref : J Enzyme Inhib Med Chem , 22 :407 , 2007
PubMedID: 17847706

Title : Structural insights into substrate traffic and inhibition in acetylcholinesterase - Colletier_2006_EMBO.J_25_2746
Author(s) : Colletier JP , Fournier D , Greenblatt HM , Stojan J , Sussman JL , Zaccai G , Silman I , Weik M
Ref : EMBO Journal , 25 :2746 , 2006
PubMedID: 16763558
Gene_locus related to this paper: torca-ACHE

Title : Rational polynomial equation helps to select among homeomorphic kinetic models for cholinesterase reaction mechanism - Stojan_2005_Chem.Biol.Interact_157-158_173
Author(s) : Stojan J
Ref : Chemico-Biological Interactions , 157-158 :173 , 2005
PubMedID: 16256094

Title : Acetylcholinesterase alterations reveal the fitness cost of mutations conferring insecticide resistance - Shi_2004_BMC.Evol.Biol_4_5
Author(s) : Shi MA , Lougarre A , Alies C , Fremaux I , Tang ZH , Stojan J , Fournier D
Ref : BMC Evol Biol , 4 :5 , 2004
PubMedID: 15018650

Title : Comparison of two reaction schemes for the hydrolysis of acetylthiocholine by butyrylcholinesterase. -
Author(s) : Simeon-Rudolf V , Sinko G , Stuglin A , Stojan J , Golicnik M
Ref : Cholinergic Mechanisms, CRC Press :701 , 2004
PubMedID:

Title : Inhibition of Drosophila melanogaster acetylcholinesterase by high concentrations of substrate - Stojan_2004_Eur.J.Biochem_271_1364
Author(s) : Stojan J , Brochier L , Alies C , Colletier JP , Fournier D
Ref : European Journal of Biochemistry , 271 :1364 , 2004
PubMedID: 15030487

Title : Rational polynomial equation as an unbiased approach for the kinetic studies of Drosophila melanogaster acetylcholinesterase reaction mechanism - Stojan_2004_Biochim.Biophys.Acta_1703_53
Author(s) : Stojan J , Golicnik M , Fournier D
Ref : Biochimica & Biophysica Acta , 1703 :53 , 2004
PubMedID: 15588702

Title : Kinetics of ethopropazine binding to butyrylcholinesterase in the absence and presence of acetylthiocholine -
Author(s) : Reiner E , Sinko G , Bosak A , Simeon-Rudolf V , Radic Z , Taylor P , Stojan J , Golicnik M
Ref : In: Cholinesterases in the Second Millennium: Biomolecular and Pathological Aspects , (Inestrosa NC, Campos EO) P. Universidad Catolica de Chile-FONDAP Biomedicina :187 , 2004
PubMedID:

Title : Poster (19) Kinetics of ethopropazine binding to butyrylcholinesterase in the absence and presence of acetylthiocholine. -
Author(s) : Reiner E , Sinko G , Stuglin A , Simeon-Rudolf V , Radic Z , Taylor P , Stojan J , Golicnik M
Ref : In: Cholinesterases in the Second Millennium: Biomolecular and Pathological Aspects , (Inestrosa NC, Campos EO) P. Universidad Catolica de Chile-FONDAP Biomedicina :330 , 2004
PubMedID:

Title : Significance of parameters in various kinetic schemes for cholinesterases. -
Author(s) : Stojan J , Golicnik M
Ref : Cholinergic Mechanisms, CRC Press :721 , 2004
PubMedID:

Title : New biosensors for improved detection of environmental and food contamination by anticholinesterase pesticides -
Author(s) : Toutant JP , Massoulie J , Fournier D , Marty JL , Schmid RD , Pfeiffer D , Selkirk ME , Sussman JL , Silman I , Talesa V , Wodak SJ , Stojan J , Magearu V
Ref : In: Cholinesterases in the Second Millennium: Biomolecular and Pathological Aspects , (Inestrosa NC, Campos EO) P. Universidad Catolica de Chile-FONDAP Biomedicina :233 , 2004
PubMedID:

Title : Generalized theoretical and practical treatment of the kinetics of an enzyme-catalyzed reaction in the presence of an enzyme equimolar irreversible inhibitor - Golicnik_2003_J.Chem.Inf.Comput.Sci_43_1486
Author(s) : Golicnik M , Stojan J
Ref : J Chem Inf Comput Sci , 43 :1486 , 2003
PubMedID: 14502482

Title : Concentration-dependent reversible activation-inhibition of human butyrylcholinesterase by tetraethylammonium ion - Stojan_2002_Eur.J.Biochem_269_1154
Author(s) : Stojan J , Golicnik M , Froment MT , Estour F , Masson P
Ref : European Journal of Biochemistry , 269 :1154 , 2002
PubMedID: 11856351

Title : Multi-step analysis as a tool for kinetic parameter estimation and mechanism discrimination in the reaction between tight-binding fasciculin 2 and electric eel acetylcholinesterase - Golicnik_2002_Biochim.Biophys.Acta_1597_164
Author(s) : Golicnik M , Stojan J
Ref : Biochimica & Biophysica Acta , 1597 :164 , 2002
PubMedID: 12009416

Title : Transient kinetic approach to the study of acetylcholinesterase reversible inhibition by eseroline - Golicnik_2002_J.Enzyme.Inhib.Med.Chem_17_279
Author(s) : Golicnik M , Stojan J
Ref : J Enzyme Inhib Med Chem , 17 :279 , 2002
PubMedID: 12683744

Title : Acceleration of Drosophila melanogaster acetylcholinesterase methanesulfonylation: peripheral ligand D-tubocurarine enhances the affinity for small methanesulfonylfluoride - Golicnik_2002_Chem.Biol.Interact_139_145
Author(s) : Golicnik M , Fournier D , Stojan J
Ref : Chemico-Biological Interactions , 139 :145 , 2002
PubMedID: 11823003

Title : Kinetic Model of Ethopropazine Interaction with Horse Serum Butyrylcholinesterase and Its Docking into the Active Site - Golicnik_2002_Arch.Biochem.Biophys_398_23
Author(s) : Golicnik M , Sinko G , Simeon-Rudolf V , Grubic Z , Stojan J
Ref : Archives of Biochemistry & Biophysics , 398 :23 , 2002
PubMedID: 11811945

Title : Interaction of Drosophila acetylcholinesterases with D-tubocurarine: an explanation of the activation by an inhibitor - Golicnik_2001_Biochemistry_40_1214
Author(s) : Golicnik M , Fournier D , Stojan J
Ref : Biochemistry , 40 :1214 , 2001
PubMedID: 11170446

Title : Slow detection reaction can mimic initial inhibition of an enzymic reaction - Stojan_2001_J.Enzyme.Inhib_16_89
Author(s) : Stojan J
Ref : J Enzyme Inhib , 16 :89 , 2001
PubMedID: 11342277

Title : Exploration of the Drosophila acetylcholinesterase substrate activation site using a reversible inhibitor (Triton X-100) and mutated enzymes - Marcel_2000_J.Biol.Chem_275_11603
Author(s) : Marcel V , Estrada-Mondaca S , Magne F , Stojan J , Klaebe A , Fournier D
Ref : Journal of Biological Chemistry , 275 :11603 , 2000
PubMedID: 10766776

Title : Inhibition of Drosophila acetylcholinesterase by 7-(methylethoxyphosphinyloxy)1-methyl-quinolinium iodide - Stojan_1999_Chem.Biol.Interact_119-120_147
Author(s) : Stojan J , Marcel V , Fournier D
Ref : Chemico-Biological Interactions , 119-120 :147 , 1999
PubMedID: 10421448

Title : Electron paramagnetic resonance reveals altered topography of the active center gorge of acetylcholinesterase after binding of fasciculin to the peripheral site - Sentjurc_1999_Biochim.Biophys.Acta_1430_349
Author(s) : Sentjurc M , Pecar S , Stojan J , Marchot P , Radic Z , Grubic Z
Ref : Biochimica & Biophysica Acta , 1430 :349 , 1999
PubMedID: 10082962

Title : Homology built model of acetylcholinesterase from Drosophila melanogaster - Stojan_1999_J.Enzyme.Inhib_14_193
Author(s) : Stojan J
Ref : J Enzyme Inhib , 14 :193 , 1999
PubMedID: 10445043

Title : Effect of tetramethylammonium, choline and edrophonium on insect acetylcholinesterase: test of a kinetic model - Stojan_1999_Chem.Biol.Interact_119-120_137
Author(s) : Stojan J , Marcel V , Fournier D
Ref : Chemico-Biological Interactions , 119-120 :137 , 1999
PubMedID: 10421447

Title : A putative kinetic model for substrate metabolisation by Drosophila acetylcholinesterase - Stojan_1998_FEBS.Lett_440_85
Author(s) : Stojan J , Marcel V , Estrada-Mondaca S , Klaebe A , Masson P , Fournier D
Ref : FEBS Letters , 440 :85 , 1998
PubMedID: 9862431

Title : Kinetic characterization of all steps of the interaction between acetylcholinesterase and eserine - Stojan_1997_Biochim.Biophys.Acta_1337_75
Author(s) : Stojan J , Zorko M
Ref : Biochimica & Biophysica Acta , 1337 :75 , 1997
PubMedID: 9003439

Title : Mechanism of eserine action on the hydrolysis of butyrylthiocholine by butyrylcholinesterase - Stojan_1997_J.Enzyme.Inhib_11_199
Author(s) : Stojan J , Pavlic MR
Ref : J Enzyme Inhib , 11 :199 , 1997
PubMedID: 9204388

Title : The influence of an organosulfonate on the reaction between Ellman's reagent and thiocholine - Stojan_1994_J.Analyt.Toxico_18_165
Author(s) : Stojan J , Pavlic MR
Ref : Journal of Analytical Toxicology , 18 :165 , 1994
PubMedID: 8065127

Title : Velocity of Ellman's reaction and its implication for kinetic studies in the millisecond time range - Stojan_1992_Neurochem.Res_17_1207
Author(s) : Stojan J , Pavlic MR
Ref : Neurochem Res , 17 :1207 , 1992
PubMedID: 1461367

Title : On the inhibition of cholinesterase by D-tubocurarine - Stojan_1991_Biochim.Biophys.Acta_1079_96
Author(s) : Stojan J , Pavlic MR
Ref : Biochimica & Biophysica Acta , 1079 :96 , 1991
PubMedID: 1888768

Title : Poster 5. Time course of inhibition of cholinesterase by D-tubocurarine -
Author(s) : Stojan J , Zorko M , Pavlic MR
Ref : In: Cholinesterases, fundamental and applied aspects : proceedings of the Second International Meeting on Cholinesterases , (Brzin M, Barnard EA, Sket D, Eds) De Gruyter , 1984
PubMedID: