Gene Locus : human-BCHE
Mode of mutation : Site directed mutagenesis
Disease :
Summary : Oxyanion hole no activity Loewenstein-Lichtenstein_1996_Mol.Pharmacol_50_1423
AAA Change :
Allelic Variant :
Risk Factor :
Inhibitor :
Structure :
Disease by interaction :
Interact Gene Locus :
Xenobiotic sensitivity :
Modification : Oxyanion hole
Torpedo_number : 118
Kinetic Parameter : Butyrylthiocholine_G116E_human-BCHE
News : No news
Comment :
p.G116E Gly116Glu (p.G144E Gly144Glu in primary sequence with 28 amino-acids signal peptide) Oxyanion hole\; no activity
| Title : Overlapping drug interaction sites of human butyrylcholinesterase dissected by site-directed mutagenesis - Loewenstein-Lichtenstein_1996_Mol.Pharmacol_50_1423 |
| Author(s) : Loewenstein-Lichtenstein Y , Glick D , Gluzman N , Sternfeld M , Zakut H , Soreq H |
| Ref : Molecular Pharmacology , 50 :1423 , 1996 |
| Abstract : |
| PubMedSearch : Loewenstein-Lichtenstein_1996_Mol.Pharmacol_50_1423 |
| PubMedID: 8967962 |
| Gene_locus related to this paper: human-BCHE |