Zakut H

General

Full name : Zakut Haim

First name : Haim

Mail : The Edith Wolfson Med. Center, Dept. of Obstetrics & Gynecology, P.O.B. 5, 58100 Holon

Zip Code :

City :

Country : Israel

Email :

Phone : (972) 3 5028712

Fax : (972) 3 5014111

Website :

Directory :

References (49)

Title : Normal and atypical butyrylcholinesterases in placental development, function, and malfunction - Sternfeld_1997_Cell.Mol.Neurobiol_17_315
Author(s) : Sternfeld M , Rachmilewitz J , Loewenstein-Lichtenstein Y , Andres C , Timberg R , Ben-Ari S , Glick C , Soreq H , Zakut H
Ref : Cellular Molecular Neurobiology , 17 :315 , 1997
PubMedID: 9187488

Title : Overlapping drug interaction sites of human butyrylcholinesterase dissected by site-directed mutagenesis - Loewenstein-Lichtenstein_1996_Mol.Pharmacol_50_1423
Author(s) : Loewenstein-Lichtenstein Y , Glick D , Gluzman N , Sternfeld M , Zakut H , Soreq H
Ref : Molecular Pharmacology , 50 :1423 , 1996
PubMedID: 8967962
Gene_locus related to this paper: human-BCHE

Title : Genetic predisposition to adverse consequences of anti-cholinesterases in 'atypical' BCHE carriers - Loewenstein-Lichtenstein_1995_Nat.Med_1_1082
Author(s) : Loewenstein-Lichtenstein Y , Schwarz M , Glick D , Norgaard-Pedersen B , Zakut H , Soreq H
Ref : Nat Med , 1 :1082 , 1995
PubMedID: 7489367

Title : Genetic Predisposition for Variable Response to Anticholinesterase Therapy Anticipated in Carriers of the Butyrylcholinesterase Atypical Mutation -
Author(s) : Loewenstein Y , Schwarz M , Glick D , Norgaard-Pedersen B , Zakut H , Soreq H
Ref : In Enzyme of the Cholinesterase Family - Proceedings of Fifth International Meeting on Cholinesterases , (Quinn, D.M., Balasubramanian, A.S., Doctor, B.P., Taylor, P., Eds) Plenum Publishing Corp. :471 , 1995
PubMedID:

Title : Antisense Oligonucleotides Suppressing Expression of Cholinesterase Genes Modulate Hematopoiesis in Vivo and ex Vivo -
Author(s) : Soreq H , Lev-Lehman E , Patinkin D , Grifman M , Ehrlich G , Ginzberg D , Eckstein F , Zakut H
Ref : In Enzyme of the Cholinesterase Family - Proceedings of Fifth International Meeting on Cholinesterases , (Quinn, D.M., Balasubramanian, A.S., Doctor, B.P., Taylor, P., Eds) Plenum Publishing Corp. :1 , 1995
PubMedID:

Title : HER-2 amplification but not butyrylcholinesterase multability reflects aggressiveness of European-originated ovarian tumors - Dobianer_1995_Gynecol.Oncol_56_200
Author(s) : Dobianer K , Hruza C , Ehrlich G , Sevelda P , Czerwenka K , Soreq H , Spona J , Zakut H
Ref : Gynecologic Oncology , 56 :200 , 1995
PubMedID: 7896186

Title : Antisense inhibition of acetylcholinesterase gene expression causes transient hematopoietic alterations in vivo - Lev-Lehman_1994_Gene.Ther_1_127
Author(s) : Lev-Lehman E , Ginzberg D , Hornreich G , Ehrlich G , Meshorer A , Eckstein F , Soreq H , Zakut H
Ref : Gene Therapy , 1 :127 , 1994
PubMedID: 7584068

Title : Use of partially phosphorothioated antisense oligodeoxynucleotides for sequence-dependent modulation of hematopoiesis in culture - Ehrlich_1994_Antisense.Res.Dev_4_173
Author(s) : Ehrlich G , Patinkin D , Ginzberg D , Zakut H , Eckstein F , Soreq H
Ref : Antisense Research Development , 4 :173 , 1994
PubMedID: 7849488

Title : Testicular amplification and impaired transmission of human butyrylcholinesterase cDNA in transgenic mice - Beeri_1994_Hum.Reprod_9_284
Author(s) : Beeri R , Gnatt A , Lapidot-Lifson Y , Ginzberg D , Shani M , Soreq H , Zakut H
Ref : Hum Reprod , 9 :284 , 1994
PubMedID: 8027285

Title : Population diversity and distinct haplotype frequencies associated with ACHE and BCHE genes of Israeli Jews from trans-Caucasian Georgia and from Europe - Ehrlich_1994_Genomics_22_288
Author(s) : Ehrlich G , Ginzberg D , Loewenstein Y , Glick D , Kerem B , Ben-Ari S , Zakut H , Soreq H
Ref : Genomics , 22 :288 , 1994
PubMedID: 7806214

Title : Expression of three alternative acetylcholinesterase messenger RNAs in human tumor cell lines of different tissue origins - Karpel_1994_Exp.Cell.Res_210_268
Author(s) : Karpel R , Ben-Aziz-Aloya R , Sternfeld M , Ehrlich G , Ginzberg D , Tarroni P , Clementi F , Zakut H , Soreq H
Ref : Experimental Cell Research , 210 :268 , 1994
PubMedID: 8299725

Title : Mutations and impaired expression in the ACHE and BCHE genes: neurological implications - Soreq_1994_Biomed.Pharmacother_48_253
Author(s) : Soreq H , Ehrlich G , Schwarz M , Loewenstein Y , Glick D , Zakut H
Ref : Biomed Pharmacother , 48 :253 , 1994
PubMedID: 7999987

Title : Antisense oligonucleotide inhibition of acetylcholinesterase gene expression induces progenitor cell expansion and suppresses hematopoietic apoptosis ex vivo - Soreq_1994_Proc.Natl.Acad.Sci.U.S.A_91_7907
Author(s) : Soreq H , Patinkin D , Lev-Lehman E , Grifman M , Ginzberg D , Eckstein F , Zakut H
Ref : Proc Natl Acad Sci U S A , 91 :7907 , 1994
PubMedID: 8058733

Title : Antisense inhibition of butyrylcholinesterase gene expression predicts adverse hematopoietic consequences to cholinesterase inhibitors - Patinkin_1994_Cell.Mol.Neurobiol_14_459
Author(s) : Patinkin D , Lev-Lehman E , Zakut H , Eckstein F , Soreq H
Ref : Cellular Molecular Neurobiology , 14 :459 , 1994
PubMedID: 7621507

Title : Expression of a human acetylcholinesterase promoter-reporter construct in developing neuromuscular junctions of Xenopus embryos - Ben-Aziz-Aloya_1993_Proc.Natl.Acad.Sci.U.S.A_90_2471
Author(s) : Ben-Aziz-Aloya R , Seidman S , Timberg R , Sternfeld M , Zakut H , Soreq H
Ref : Proceedings of the National Academy of Sciences of the United States of America , 90 :2471 , 1993
PubMedID: 8460160

Title : Molecular dissection of cholinesterase domains responsible for carbamate toxicity - Loewenstein_1993_Chem.Biol.Interact_87_209
Author(s) : Loewenstein Y , Denarie M , Zakut H , Soreq H
Ref : Chemico-Biological Interactions , 87 :209 , 1993
PubMedID: 8343977

Title : Structure-function relationship studies in human cholinesterases reveal genomic origins for individual variations in cholinergic drug responses. - Loewenstein_1993_Prog.Neuropsychopharmacol.Biol.Psychiatry_17_905
Author(s) : Loewenstein Y , Gnatt A , Neville LF , Zakut H , Soreq H
Ref : Prog Neuropsychopharmacol Biological Psychiatry , 17 :905 , 1993
PubMedID: 8278601

Title : In vivo gene amplification in non-cancerous cells: cholinesterase genes and oncogenes amplify in thrombocytopenia associated with lupus erythematosus - Zakut_1992_Mut.Res_276_275
Author(s) : Zakut H , Lapidot-Lifson Y , Beeri R , Ballin A , Soreq H
Ref : Mutation Research , 276 :275 , 1992
PubMedID: 1374519

Title : Mapping the human acetylcholinesterase gene to chromosome 7q22 by fluorescent in situ hybridization coupled with selective PCR amplification from a somatic hybrid cell panel and chromosome-sorted DNA libraries - Ehrlich_1992_Genomics_13_1192
Author(s) : Ehrlich G , Viegas-Pequignot E , Ginzberg D , Sindel L , Soreq H , Zakut H
Ref : Genomics , 13 :1192 , 1992
PubMedID: 1380483

Title : Clinical Implications of Cholinesterase Aberrations in Syndromes of Hemopoietic Cell Division -
Author(s) : Zakut H , Lapidot-Lifson Y
Ref : In Multidisciplinary approaches to cholinesterase functions - Proceedings of Fourth International Meeting on Cholinesterases , (Shafferman, A. and Velan, B., Eds) Plenum Press, New York :269 , 1992
PubMedID:

Title : [Medical aspects and structural implications of cholinesterase inhibitors] -
Author(s) : Soreq H , Meir R , Zakut H
Ref : Harefuah , 123 :100 , 1992
PubMedID: 1516859

Title : Cloning and antisense oligodeoxynucleotide inhibition of a human homolog of cdc2 required in hematopoiesis - Lapidot-Lifson_1992_Proc.Natl.Acad.Sci.U.S.A_89_579
Author(s) : Lapidot-Lifson Y , Patinkin D , Prody CA , Ehrlich G , Seidman S , Ben-Aziz R , Benseler F , Eckstein F , Zakut H , Soreq H
Ref : Proc Natl Acad Sci U S A , 89 :579 , 1992
PubMedID: 1731328

Title : A role for cholinesterases in tumorigenesis?. [Review] [48 refs] - Soreq_1991_Cancer.Cells_3_511
Author(s) : Soreq H , Lapidot-Lifson Y , Zakut H
Ref : Cancer Cells , 3 :511 , 1991
PubMedID: 1820094

Title : Human acetylcholinesterase and butyrylcholinesterase are encoded by two distinct genes - Gnatt_1991_Cell.Mol.Neurobiol_11_91
Author(s) : Gnatt A , Ginzberg D , Lieman-Hurwitz J , Zamir R , Zakut H , Soreq H
Ref : Cellular Molecular Neurobiology , 11 :91 , 1991
PubMedID: 2013062

Title : Search for the Molecular Origins of Butyrylcholinesterase Polymorphism by cDNA Screening, Deletion Mutagenesis, and Xenopus Oocyte Co-Injections -
Author(s) : Dreyfus PA , Pincon-Raymond M , Zakut H , Seidman S , Soreq H
Ref : In: Cholinesterases: Structure, Function, Mechanism, Genetics, and Cell Biology , (Massoulie J, Barnard EA, Chatonnet A, Bacou F, Doctor BP, Quinn DM) American Chemical Society, Washington, DC :162 , 1991
PubMedID:

Title : Differential Codon Usage and Distinct Surface Probabilities in Human Acetylcholinesterase and Butyrylcholinesterase -
Author(s) : Ben-Aziz R , Gnatt A , Prody C , Lev-Lehman E , Neville LF , Seidman S , Ginzberg D , Soreq H , Lapidot-Lifson Y , Zakut H
Ref : In: Cholinesterases: Structure, Function, Mechanism, Genetics, and Cell Biology , (Massoulie J, Barnard EA, Chatonnet A, Bacou F, Doctor BP, Quinn DM) American Chemical Society, Washington, DC :172 , 1991
PubMedID:

Title : Chorionic villus cDNA library displays expression of butyrylcholinesterase: putative genetic disposition for ecological danger - Zakut_1991_Prenat.Diagnos_11_597
Author(s) : Zakut H , Lieman-Hurwitz J , Zamir R , Sindell L , Ginzberg D , Soreq H
Ref : Prenat Diagnos , 11 :597 , 1991
PubMedID: 1722578

Title : Expression of alternatively terminated unusual human butyrylcholinesterase messenger RNA transcripts, mapping to chromosome 3q26-ter, in nervous system tumors - Gnatt_1990_Cancer.Res_50_1983
Author(s) : Gnatt A , Prody CA , Zamir R , Lieman-Hurwitz J , Zakut H , Soreq H
Ref : Cancer Research , 50 :1983 , 1990
PubMedID: 2317787

Title : Acetylcholinesterase and butyrylcholinesterase genes coamplify in primary ovarian carcinomas - Zakut_1990_J.Clin.Invest_86_900
Author(s) : Zakut H , Ehrlich G , Ayalon A , Prody CA , Malinger G , Seidman S , Ginzberg D , Kehlenbach R , Soreq H
Ref : Journal of Clinical Investigation , 86 :900 , 1990
PubMedID: 2394839

Title : Amplification of butyrylcholinesterase and acetylcholinesterase genes in normal and tumor tissues: putative relationship to organophosphorous poisoning - Soreq_1990_Pharm.Res_7_1
Author(s) : Soreq H , Zakut H
Ref : Pharm Res , 7 :1 , 1990
PubMedID: 2405380

Title : Expression and in vivo amplification of the human acetylcholinesterase and butyrylcholinesterase genes -
Author(s) : Soreq H , Zakut H
Ref : Prog Brain Res , 84 :51 , 1990
PubMedID: 2267318

Title : Manipulations of cholinesterase gene expression modulate murine megakaryocytopoiesis in vitro - Patinkin_1990_Mol.Cell.Biol_10_6046
Author(s) : Patinkin D , Seidman S , Eckstein F , Benseler F , Zakut H , Soreq H
Ref : Molecular & Cellular Biology , 10 :6046 , 1990
PubMedID: 2233731

Title : Tissue-specific processing and polarized compartmentalization of clone-produced cholinesterase in microinjected Xenopus oocytes - Dreyfus_1989_Cell.Mol.Neurobiol_9_323
Author(s) : Dreyfus PA , Seidman S , Pincon-Raymond M , Murawsky M , Rieger F , Schejter E , Zakut H , Soreq H
Ref : Cellular Molecular Neurobiology , 9 :323 , 1989
PubMedID: 2692828

Title : De novo amplification within a silent human cholinesterase gene in a family subjected to prolonged exposure to organophosphorous insecticides - Prody_1989_Proc.Natl.Acad.Sci.U.S.A_86_690
Author(s) : Prody CA , Dreyfus PA , Zamir R , Zakut H , Soreq H
Ref : Proceedings of the National Academy of Sciences of the United States of America , 86 :690 , 1989
PubMedID: 2911599

Title : Definition, at the molecular level, of a thyroglobulin- acetylcholinesterase shared epitope: study of its pathophysiological significance in patients with Graves' ophthalmopathy - Ludgate_1989_Autoimmunity_3_167
Author(s) : Ludgate M , Dong Q , Dreyfus PA , Zakut H , Taylor P , Vassart G , Soreq H
Ref : Autoimmunity , 3 :167 , 1989
PubMedID: 2485081

Title : Gene mapping on chorionic villi chromosomes by hybridization in situ: localization of cholinesterase cDNA binding sites to chromosomes 3q21, 3q26-ter and 16q21 - Zakut_1989_Hum.Reprod_4_941
Author(s) : Zakut H , Zamir R , Sindel L , Soreq H
Ref : Hum Reprod , 4 :941 , 1989
PubMedID: 2613865

Title : [In-situ hybridization on chorionic villi chromosomes]. [Hebrew] - Zakut_1989_Harefuah_116_81
Author(s) : Zakut H , Zamir R , Soreq H
Ref : Harefuah , 116 :81 , 1989
PubMedID: 2707673

Title : Expression and tissue-specific assembly of human butyrylcholine esterase in microinjected Xenopus laevis oocytes - Soreq_1989_J.Biol.Chem_264_10608
Author(s) : Soreq H , Seidman S , Dreyfus PA , Zevin-Sonkin D , Zakut H
Ref : Journal of Biological Chemistry , 264 :10608 , 1989
PubMedID: 2732242

Title : Coamplification of human acetylcholinesterase and butyrylcholinesterase genes in blood cells: correlation with various leukemias and abnormal megakaryocytopoiesis - Lapidot-Lifson_1989_Proc.Natl.Acad.Sci.U.S.A_86_4715
Author(s) : Lapidot-Lifson Y , Prody CA , Ginzberg D , Meytes D , Zakut H , Soreq H
Ref : Proceedings of the National Academy of Sciences of the United States of America , 86 :4715 , 1989
PubMedID: 2734315

Title : Cholinoceptive properties of human primordial, preantral, and antral oocytes: in situ hybridization and biochemical evidence for expression of cholinesterase genes - Malinger_1989_J.Mol.Neurosci_1_77
Author(s) : Malinger G , Zakut H , Soreq H
Ref : Journal of Molecular Neuroscience , 1 :77 , 1989
PubMedID: 2641279

Title : Modified properties of serum cholinesterases in primary carcinomas - Zakut_1988_Cancer_61_727
Author(s) : Zakut H , Even L , Birkenfeld S , Malinger G , Zisling R , Soreq H
Ref : Cancer , 61 :727 , 1988
PubMedID: 3338035

Title : Antibodies against acetylcholinesterase and low levels of cholinesterases in a patient with an atypical neuromuscular disorder - Livneh_1988_Clin.Immunol.Immunopath_48_119
Author(s) : Livneh A , Sarova I , Michaeli D , Pras M , Wagner K , Zakut H , Soreq H
Ref : Clinical Immunology & Immunopathology , 48 :119 , 1988
PubMedID: 3390968

Title : Cross-homologies and structural differences between human cholinesterases revealed by antibodies against cDNA-produced human butyrylcholinesterase peptides - Dreyfus_1988_J.Neurochem_51_1858
Author(s) : Dreyfus PA , Zevin-Sonkin D , Seidman S , Prody CA , Zisling R , Zakut H , Soreq H
Ref : Journal of Neurochemistry , 51 :1858 , 1988
PubMedID: 2460589

Title : Human cholinesterase genes localized by hybridization to chromosomes 3 and 16 - Soreq_1987_Hum.Genet_77_325
Author(s) : Soreq H , Zamir R , Zevin-Sonkin D , Zakut H
Ref : Hum Genet , 77 :325 , 1987
PubMedID: 3692476

Title : Expression of cholinesterase genes in human oocytes revealed by in-situ hybridization - Soreq_1987_Hum.Reprod_2_689
Author(s) : Soreq H , Malinger G , Zakut H
Ref : Hum Reprod , 2 :689 , 1987
PubMedID: 2830295

Title : Synthesis of plasma proteins in fetal, adult, and neoplastic human brain tissue - Dziegielewska_1986_Dev.Biol_115_93
Author(s) : Dziegielewska KM , Saunders NR , Schejter EJ , Zakut H , Zevin-Sonkin D , Zisling R , Soreq H
Ref : Developmental Biology , 115 :93 , 1986
PubMedID: 2422074

Title : Divergent regulation of muscarinic binding sites and acetylcholinesterase in discrete regions of the developing human fetal brain - Egozi_1986_Cell.Mol.Neurobiol_6_55
Author(s) : Egozi Y , Sokolovsky M , Schejter E , Blatt I , Zakut H , Matzkel A , Soreq H
Ref : Cellular Molecular Neurobiology , 6 :55 , 1986
PubMedID: 3719620

Title : The use of mRNA translation in vitro and in ovo followed by crossed immunoelectrophoretic autoradiography to study the biosynthesis of human cholinesterases - Soreq_1986_Cell.Mol.Neurobiol_6_227
Author(s) : Soreq H , Dziegielewska KM , Zevin-Sonkin D , Zakut H
Ref : Cellular Molecular Neurobiology , 6 :227 , 1986
PubMedID: 3802131

Title : Polymorphism of acetylcholinesterase in discrete regions of the developing human fetal brain - Zakut_1985_J.Neurochem_45_382
Author(s) : Zakut H , Matzkel A , Schejter E , Avni A , Soreq H
Ref : Journal of Neurochemistry , 45 :382 , 1985
PubMedID: 4009167