G121A_human-ACHE

General

Gene Locus : human-ACHE

Mode of mutation : Site directed mutagenesis

Disease :

Summary : Oxyanion hole\;Alteration of oxyanion hole structure\;Ordentlich_1998_J.Biol.Chem_273_19509

AAA Change :

Allelic Variant :

Risk Factor :

Inhibitor :

Structure :

Disease by interaction :

Interact Gene Locus :

Xenobiotic sensitivity :

Modification : Oxyanion hole

Torpedo_number : 118

Kinetic Parameter : No kinetic parameter

News : No news

Comment : "p.Gly121Ala (p.G152A Gly152Ala in primary sequence with 31 amino-acids signal peptide) Oxyanion hole\;Alteration of oxyanion hole structure"

References (1)

Title : Functional characteristics of the oxyanion hole in human acetylcholinesterase - Ordentlich_1998_J.Biol.Chem_273_19509
Author(s) : Ordentlich A , Barak D , Kronman C , Ariel N , Segall Y , Velan B , Shafferman A
Ref : Journal of Biological Chemistry , 273 :19509 , 1998
Abstract : Ordentlich_1998_J.Biol.Chem_273_19509
ESTHER : Ordentlich_1998_J.Biol.Chem_273_19509
PubMedSearch : Ordentlich_1998_J.Biol.Chem_273_19509
PubMedID: 9677373