L366F_drome-ACHE

General

Gene Locus : drome-ACHE

Mode of mutation : Site directed mutagenesis

Disease :

Summary : Insecticide sensitivity Boublik_2002_Protein.Eng_15_43 || Binding of Triton X-100 studies mutation mimic the torpedo enzyme, no effect Marcel_2000_J.Biol.Chem_275_11603

AAA Change :

Allelic Variant :

Risk Factor :

Inhibitor :

Structure :

Disease by interaction :

Interact Gene Locus :

Xenobiotic sensitivity :

Modification : Insecticide sensitivity || Binding of Triton X-100 studies

Torpedo_number : 288

Kinetic Parameter : No kinetic parameter

News : No news

Comment :
Mutation L328F in mature protein. Numbering in Boublik et al. 2002 || p.Leu366Phe

References (2)

Title : Acetylcholinesterase engineering for detection of insecticide residues - Boublik_2002_Protein.Eng_15_43
Author(s) : Boublik Y , Saint-Aguet P , Lougarre A , Arnaud M , Villatte F , Estrada-Mondaca S , Fournier D
Ref : Protein Engineering , 15 :43 , 2002
Abstract :
PubMedSearch : Boublik_2002_Protein.Eng_15_43
PubMedID: 11842237

Title : Exploration of the Drosophila acetylcholinesterase substrate activation site using a reversible inhibitor (Triton X-100) and mutated enzymes - Marcel_2000_J.Biol.Chem_275_11603
Author(s) : Marcel V , Estrada-Mondaca S , Magne F , Stojan J , Klaebe A , Fournier D
Ref : Journal of Biological Chemistry , 275 :11603 , 2000
Abstract :
PubMedSearch : Marcel_2000_J.Biol.Chem_275_11603
PubMedID: 10766776