Q281R_human-PLA2G7

General

Gene Locus : human-PLA2G7

Mode of mutation : Natural mutant

Disease : Suceptibility to asthma and atopy, Platelet-activating factor acetylhydrolase (PLA2G7) deficiency (PAFAD) coronary artery disease risk factor

Summary :

AAA Change :

Allelic Variant :

Risk Factor :

Inhibitor :

Structure :

Disease by interaction :

Interact Gene Locus :

Xenobiotic sensitivity :

Modification :

Torpedo_number : No torpedo number

Kinetic Parameter : No kinetic parameter

News : No news

Comment :
p.Q281R Gln281Arg rs201256712

References (3)

Title : Structural Modeling of Wild and Mutant Forms of Human Plasma Platelet Activating Factor-Acetyl Hydrolase Enzyme - Khan_2020_J.Inflamm.Res_13_1125
Author(s) : Khan MI , Hariprasad G
Ref : J Inflamm Res , 13 :1125 , 2020
PubMedID: 33364808
Gene_locus related to this paper: human-PLA2G7

Title : Deficiency of platelet-activating factor acetylhydrolase is a severity factor for asthma - Stafforini_1999_J.Clin.Invest_103_989
Author(s) : Stafforini DM , Numao T , Tsodikov A , Vaitkus D , Fukuda T , Watanabe N , Fueki N , McIntyre TM , Zimmerman GA , Makino S , Prescott SM
Ref : J Clinical Investigation , 103 :989 , 1999
PubMedID: 10194471
Gene_locus related to this paper: human-PLA2G7

Title : Loss of activity of plasma platelet-activating factor acetylhydrolase due to a novel Gln281-->Arg mutation - Yamada_1997_Biochem.Biophys.Res.Commun_236_772
Author(s) : Yamada Y , Yokota M
Ref : Biochemical & Biophysical Research Communications , 236 :772 , 1997
PubMedID: 9245731
Gene_locus related to this paper: human-PLA2G7