Gene Locus : human-NLGN3
Mode of mutation : Natural mutant
Disease : Neuroligin 3 Autism AUTSX1 Asperger syndrome ASPGX1
Summary :
AAA Change :
Allelic Variant :
Risk Factor :
Inhibitor :
Structure :
Disease by interaction :
Interact Gene Locus :
Xenobiotic sensitivity :
Modification :
Torpedo_number : No torpedo number
Kinetic Parameter : No kinetic parameter
News : No news
Comment :
p.R175W c.523 C>T De Novo Female
| Title : NLGN3 autism variants have distinct functional impact on synapses and sleep behavior in Drosophila - Townsley_2026_bioRxiv__ |
| Author(s) : Townsley R , Andrews J , Srivastav S , Jangam S , Hannan S , Kanca O , Yamamoto S , Wangler MF |
| Ref : bioRxiv , : , 2026 |
| Abstract : |
| PubMedSearch : Townsley_2026_bioRxiv__ |
| PubMedID: 41929011 |
| Gene_locus related to this paper: human-NLGN3 |
| Title : The contribution of de novo coding mutations to autism spectrum disorder - Iossifov_2014_Nature_515_216 |
| Author(s) : Iossifov I , O'Roak BJ , Sanders SJ , Ronemus M , Krumm N , Levy D , Stessman HA , Witherspoon KT , Vives L , Patterson KE , Smith JD , Paeper B , Nickerson DA , Dea J , Dong S , Gonzalez LE , Mandell JD , Mane SM , Murtha MT , Sullivan CA , Walker MF , Waqar Z , Wei L , Willsey AJ , Yamrom B , Lee YH , Grabowska E , Dalkic E , Wang Z , Marks S , Andrews P , Leotta A , Kendall J , Hakker I , Rosenbaum J , Ma B , Rodgers L , Troge J , Narzisi G , Yoon S , Schatz MC , Ye K , McCombie WR , Shendure J , Eichler EE , State MW , Wigler M |
| Ref : Nature , 515 :216 , 2014 |
| Abstract : |
| PubMedSearch : Iossifov_2014_Nature_515_216 |
| PubMedID: 25363768 |
| Gene_locus related to this paper: human-NLGN3 |