W251A_luccu-E3aest7

General

Gene Locus : luccu-E3aest7

Mode of mutation : Site directed mutagenesis

Disease :

Summary : OP-resistance search for OP hydrolase and MCE activities Heidari_2004_Insect.Biochem.Mol.Biol_34_353 || Pyrethroids hydrolysis search for Pyrethroids hydrolysis activities Heidari_2005_Insect.Biochem.Mol.Biol_35_597 || Pyrethroids hydrolysis Hydrolysis of individual isomers of fluorogenic pyrethroid analogs by mutant carboxylesterases Devonshire_2007_Insect.Biochem.Mol.Biol_37_891

AAA Change :

Allelic Variant :

Risk Factor :

Inhibitor :

Structure :

Disease by interaction :

Interact Gene Locus :

Xenobiotic sensitivity :

Modification : OP-resistance || Pyrethroids hydrolysis

Torpedo_number : 233

Kinetic Parameter : No kinetic parameter

News : No news

Comment :
p.Trp251Ala

References (3)

Title : Hydrolysis of individual isomers of fluorogenic pyrethroid analogs by mutant carboxylesterases from Lucilia cuprina - Devonshire_2007_Insect.Biochem.Mol.Biol_37_891
Author(s) : Devonshire AL , Heidari R , Huang HZ , Hammock BD , Russell RJ , Oakeshott JG
Ref : Insect Biochemistry & Molecular Biology , 37 :891 , 2007
PubMedID: 17681228
Gene_locus related to this paper: luccu-E3aest7

Title : Hydrolysis of pyrethroids by carboxylesterases from Lucilia cuprina and Drosophila melanogaster with active sites modified by in vitro mutagenesis - Heidari_2005_Insect.Biochem.Mol.Biol_35_597
Author(s) : Heidari R , Devonshire AL , Campbell BE , Dorrian SJ , Oakeshott JG , Russell RJ
Ref : Insect Biochemistry & Molecular Biology , 35 :597 , 2005
PubMedID: 15857765
Gene_locus related to this paper: drome-EST23aes07 , luccu-E3aest7

Title : Hydrolysis of organophosphorus insecticides by in vitro modified carboxylesterase E3 from Lucilia cuprina - Heidari_2004_Insect.Biochem.Mol.Biol_34_353
Author(s) : Heidari R , Devonshire AL , Campbell BE , Bell KL , Dorrian SJ , Oakeshott JG , Russell RJ
Ref : Insect Biochemistry & Molecular Biology , 34 :353 , 2004
PubMedID: 15041019
Gene_locus related to this paper: luccu-E3aest7