Full name : Hammock Bruce D
First name : Bruce D
Mail : Department of Entomology, University of California, Davis, One Shields Avenue, Davis, CA 95616-8584
Zip Code :
City :
Country : USA
Email : bdhammock@ucdavis.edu
Phone :
Fax :
Website : \/\/www.biopestlab.ucdavis.edu\/
Directory :
Comment
| Title : Soluble epoxide hydrolase inhibition impairs triggering receptor expressed on myeloid cells-1 in periodontal tissue - Vargas_2024_J.Periodontal.Res__ |
| Author(s) : Vargas BDS , Vargas BSF , Clemente-Napimoga JT , Hammock BD , Abdalla HB , Van Dyke TE , Napimoga MH |
| Ref : J Periodontal Res , : , 2024 |
| Abstract : |
| PubMedSearch : Vargas_2024_J.Periodontal.Res__ |
| PubMedID: 39343738 |
| Title : Role of the soluble epoxide hydrolase in keratinocyte proliferation and sensitivity of skin to inflammatory stimuli - Naeem_2024_Biomed.Pharmacother_171_116127 |
| Author(s) : Naeem Z , Zukunft S , Huard A , Hu J , Hammock BD , Weigert A , Fromel T , Fleming I |
| Ref : Biomed Pharmacother , 171 :116127 , 2024 |
| Abstract : |
| PubMedSearch : Naeem_2024_Biomed.Pharmacother_171_116127 |
| PubMedID: 38198951 |
| Title : 4-Phenyl-thiazole-based dual inhibitors of fatty acid amide hydrolase and soluble epoxide hydrolase do not alleviate orofacial inflammatory pain in female rats - Carr_2024_BBA.Adv_6_100119 |
| Author(s) : Carr D , Chin C , Chacon T , Herawi MK , Gonzalez M , West R , Morisseau C , Hammock BD , Pecic S , Kandasamy R |
| Ref : BBA Adv , 6 :100119 , 2024 |
| Abstract : |
| PubMedSearch : Carr_2024_BBA.Adv_6_100119 |
| PubMedID: 39246819 |
| Title : Design and Synthesis of Dual-Targeting Inhibitors of sEH and HDAC6 for the Treatment of Neuropathic Pain and Lipopolysaccharide-Induced Mortality - Chen_2024_J.Med.Chem__ |
| Author(s) : Chen Y , Sun J , Tong H , Wang J , Cao R , Xu H , Chen L , Morisseau C , Zhang M , Shi Y , Han C , Zhuang J , Jing Y , Liu Z , Hammock BD , Chen G |
| Ref : Journal of Medicinal Chemistry , : , 2024 |
| Abstract : |
| PubMedSearch : Chen_2024_J.Med.Chem__ |
| PubMedID: 38236416 |
| Title : Effects of sEH inhibition on the eicosanoid and cytokine storms in SARS-CoV-2-infected mice - Edin_2024_Faseb.j_38_e23692 |
| Author(s) : Edin ML , Gruzdev A , Graves JP , Lih FB , Morisseau C , Ward JM , Hammock BD , Bosio CM , Zeldin DC |
| Ref : Faseb j , 38 :e23692 , 2024 |
| Abstract : |
| PubMedSearch : Edin_2024_Faseb.j_38_e23692 |
| PubMedID: 38786655 |
| Title : Enhancing cancer immunotherapy via inhibition of soluble epoxide hydrolase - Kelly_2024_Proc.Natl.Acad.Sci.U.S.A_121_e2314085121 |
| Author(s) : Kelly AG , Wang W , Rothenberger E , Yang J , Gilligan MM , Kipper FC , Attaya A , Gartung A , Hwang SH , Gillespie MJ , Bayer RL , Quinlivan KM , Torres KL , Huang S , Mitsiades N , Yang H , Hammock BD , Panigrahy D |
| Ref : Proc Natl Acad Sci U S A , 121 :e2314085121 , 2024 |
| Abstract : |
| PubMedSearch : Kelly_2024_Proc.Natl.Acad.Sci.U.S.A_121_e2314085121 |
| PubMedID: 38330013 |
| Title : Randomized, double-blind, phase 1a single-ascending dose and food effect studies assessing safety and pharmacokinetics of EC5026 in healthy volunteers - Schmidt_2024_Clin.Transl.Sci_17_e70033 |
| Author(s) : Schmidt WK , Cortes-Puch I , McReynolds CB , Croston GE , Hwang SH , Yang J , Pedersen TL , Wagner KM , Pham TT , Hunt T , Hammock BD |
| Ref : Clin Transl Sci , 17 :e70033 , 2024 |
| Abstract : |
| PubMedSearch : Schmidt_2024_Clin.Transl.Sci_17_e70033 |
| PubMedID: 39300734 |
| Title : In vivo -Active Soluble Epoxide Hydrolase-targeting PROTACs with Improved Potency and Stability - Nakane_2024_bioRxiv__ |
| Author(s) : Nakane K , Morisseau C , Dowker-Key PD , Benitez G , Aguilan JT , Nagai E , Sidoli S , Hammock BD , Bettaieb A , Shinoda K , Kitamura S |
| Ref : Biorxiv , : , 2024 |
| Abstract : |
| PubMedSearch : Nakane_2024_bioRxiv__ |
| PubMedID: 39211216 |
| Title : Design and Synthesis of sEH\/HDAC6 Dual-Targeting Inhibitors for the Treatment of Inflammatory Pain - Xu_2024_J.Med.Chem__ |
| Author(s) : Xu H , Chen Y , Tong H , Chen L , Morisseau C , Zhou Z , Zhuang J , Song C , Cai P , Liu Z , Hammock BD , Chen G |
| Ref : Journal of Medicinal Chemistry , : , 2024 |
| Abstract : |
| PubMedSearch : Xu_2024_J.Med.Chem__ |
| PubMedID: 39033411 |
| Title : Insect immune resolution with EpOME\/DiHOME and its dysregulation by their analogs leading to pathogen hypersensitivity - Hossain_2024_Insect.Biochem.Mol.Biol__104104 |
| Author(s) : Hossain Hrithik MT , Shahmohammadi N , Jin G , Lee DH , Singh N , Vik A , Hammock BD , Kim Y |
| Ref : Insect Biochemistry & Molecular Biology , :104104 , 2024 |
| Abstract : |
| PubMedSearch : Hossain_2024_Insect.Biochem.Mol.Biol__104104 |
| PubMedID: 38494144 |
| Title : Quinolinyl-based multitarget-directed ligands with soluble epoxide hydrolase and fatty acid amide hydrolase inhibitory activities: Synthetic studies and pharmacological evaluations - Angelia_2024_Heliyon_10_e32262 |
| Author(s) : Angelia J , Duong L , Yun F , Mesic A , Yuan C , Carr D , Gunari S , Hudson PK , Morisseau C , Hammock BD , Kandasamy R , Pecic S |
| Ref : Heliyon , 10 :e32262 , 2024 |
| Abstract : |
| PubMedSearch : Angelia_2024_Heliyon_10_e32262 |
| PubMedID: 38912512 |
| Title : Preclinical Evaluation of Soluble Epoxide Hydrolase Inhibitor AMHDU against Neuropathic Pain - Babkov_2024_Int.J.Mol.Sci_25_8841 |
| Author(s) : Babkov D , Eliseeva N , Adzhienko K , Bagmetova V , Danilov D , McReynolds CB , Morisseau C , Hammock BD , Burmistrov V |
| Ref : Int J Mol Sci , 25 :8841 , 2024 |
| Abstract : |
| PubMedSearch : Babkov_2024_Int.J.Mol.Sci_25_8841 |
| PubMedID: 39201526 |
| Gene_locus related to this paper: human-EPHX2 |
| Title : Inhibition of Soluble Epoxide Hydrolase Ameliorates Cerebral Blood Flow Autoregulation and Cognition in Alzheimer's Disease and Diabetes-Related Dementia Rat Models - Tang_2024_bioRxiv__ |
| Author(s) : Tang C , Border JJ , Zhang H , Gregory A , Bai S , Fang X , Liu Y , Wang S , Hwang SH , Gao W , Morgan GC , Smith J , Bunn D , Cantwell C , Wagner KM , Morisseau C , Yang J , Shin SM , O'Herron P , Bagi Z , Filosa JA , Dong Y , Yu H , Hammock BD , Roman RJ , Fan F |
| Ref : Biorxiv , : , 2024 |
| Abstract : |
| PubMedSearch : Tang_2024_bioRxiv__ |
| PubMedID: 39257786 |
| Title : Genetic deletion or pharmacological inhibition of soluble epoxide hydrolase attenuated particulate matter 2.5 exposure mediated lung injury - Zhang_2023_J.Hazard.Mater_458_131890 |
| Author(s) : Zhang J , Zhang WH , Morisseau C , Zhang M , Dong HJ , Zhu QM , Huo XK , Sun CP , Hammock BD , Ma XC |
| Ref : J Hazard Mater , 458 :131890 , 2023 |
| Abstract : |
| PubMedSearch : Zhang_2023_J.Hazard.Mater_458_131890 |
| PubMedID: 37406527 |
| Title : Adamantyl-ureas with pyrazoles substituted by fluoroalkanes as soluble epoxide hydrolase inhibitors - Burmistrov_2023_J.Fluor.Chem_266_ |
| Author(s) : Burmistrov VV , Morisseau C , Shkineva TK , Danilov DV , Gladkikh B , Butov GM , Fayzullin RR , Dutova TY , Hammock BD , Dalinger IL |
| Ref : J Fluor Chem , 266 : , 2023 |
| Abstract : |
| PubMedSearch : Burmistrov_2023_J.Fluor.Chem_266_ |
| PubMedID: 37638129 |
| Title : Soluble Epoxide Hydrolase Contributes to Cell Senescence and ER Stress in Aging Mice Colon - Wang_2023_Int.J.Mol.Sci_24_4570 |
| Author(s) : Wang W , Wagner KM , Wang Y , Singh N , Yang J , He Q , Morisseau C , Hammock BD |
| Ref : Int J Mol Sci , 24 :4570 , 2023 |
| Abstract : |
| PubMedSearch : Wang_2023_Int.J.Mol.Sci_24_4570 |
| PubMedID: 36901999 |
| Title : Macrophage Inactivation by Small Molecule Wedelolactone via Targeting sEH for the Treatment of LPS-Induced Acute Lung Injury - Zhang_2023_ACS.Cent.Sci_9_440 |
| Author(s) : Zhang J , Zhang M , Huo XK , Ning J , Yu ZL , Morisseau C , Sun CP , Hammock BD , Ma XC |
| Ref : ACS Cent Sci , 9 :440 , 2023 |
| Abstract : |
| PubMedSearch : Zhang_2023_ACS.Cent.Sci_9_440 |
| PubMedID: 36968547 |
| Title : Soluble epoxide hydrolase inhibitor blockage microglial cell activation in subnucleus caudalis in a persistent model of arthritis - Tarkany_2023_Int.Immunopharmacol_120_110320 |
| Author(s) : Tarkany Basting R , Henrique Napimoga M , Antonio Trindade Silva C , Ballassini Abdalla H , Campos Durso B , Henrique Barboza Martins L , de Abreu Cavalcanti H , Hammock BD , Trindade Clemente-Napimoga J |
| Ref : Int Immunopharmacol , 120 :110320 , 2023 |
| Abstract : |
| PubMedSearch : Tarkany_2023_Int.Immunopharmacol_120_110320 |
| PubMedID: 37230034 |
| Title : The soluble epoxide hydrolase inhibitor TPPU improves comorbidity of chronic pain and depression via the AHR and TSPO signaling - Luo_2023_J.Transl.Med_21_71 |
| Author(s) : Luo A , Wu Z , Li S , McReynolds CB , Wang D , Liu H , Huang C , He T , Zhang X , Wang Y , Liu C , Hammock BD , Hashimoto K , Yang C |
| Ref : J Transl Med , 21 :71 , 2023 |
| Abstract : |
| PubMedSearch : Luo_2023_J.Transl.Med_21_71 |
| PubMedID: 36732752 |
| Title : Quantification of soluble epoxide hydrolase inhibitors in experimental and clinical samples using the nanobody-based ELISA - Yang_2023_J.Pharm.Anal_13_1013 |
| Author(s) : Yang H , Qi M , He Q , Hwang SH , Yang J , McCoy M , Morisseau C , Zhao S , Hammock BD |
| Ref : J Pharm Anal , 13 :1013 , 2023 |
| Abstract : |
| PubMedSearch : Yang_2023_J.Pharm.Anal_13_1013 |
| PubMedID: 37842656 |
| Title : Soluble epoxide hydrolase-targeting PROTAC activates AMPK and inhibits endoplasmic reticulum stress - Peyman_2023_Biomed.Pharmacother_168_115667 |
| Author(s) : Peyman M , Barroso E , Turcu AL , Estrany F, Jr. , Smith D , Jurado-Aguilar J , Rada P , Morisseau C , Hammock BD , Valverde A M , Palomer X , Galdeano C , Vazquez S , Vazquez-Carrera M |
| Ref : Biomed Pharmacother , 168 :115667 , 2023 |
| Abstract : |
| PubMedSearch : Peyman_2023_Biomed.Pharmacother_168_115667 |
| PubMedID: 37826940 |
| Gene_locus related to this paper: human-EPHX2 |
| Title : Role of soluble epoxide hydrolase in the abnormal activation of fibroblast-like synoviocytes from patients with rheumatoid arthritis - Pu_2023_Clin.Immunol__109850 |
| Author(s) : Pu Y , Cheng R , Zhang Q , Huang T , Lu C , Tang Z , Zhong Y , Wu L , Hammock BD , Hashimoto K , Luo Y , Liu Y |
| Ref : Clin Immunol , :109850 , 2023 |
| Abstract : |
| PubMedSearch : Pu_2023_Clin.Immunol__109850 |
| PubMedID: 38013165 |
| Title : PROTAC-Mediated Selective Degradation of Cytosolic Soluble Epoxide Hydrolase Enhances ER Stress Reduction - Wang_2023_ACS.Chem.Biol__ |
| Author(s) : Wang Y , Morisseau C , Takamura A , Wan D , Li D , Sidoli S , Yang J , Wolan DW , Hammock BD , Kitamura S |
| Ref : ACS Chemical Biology , : , 2023 |
| Abstract : |
| PubMedSearch : Wang_2023_ACS.Chem.Biol__ |
| PubMedID: 36947831 |
| Gene_locus related to this paper: human-EPHX2 |
| Title : Fluorine and chlorine substituted adamantyl-urea as molecular tools for inhibition of human soluble epoxide hydrolase with picomolar efficacy - Burmistrov_2023_J.Enzyme.Inhib.Med.Chem_38_2274797 |
| Author(s) : Burmistrov VV , Morisseau C , Danilov DV , Gladkikh BP , D'Yachenko V S , Zefirov NA , Zefirova ON , Butov GM , Hammock BD |
| Ref : J Enzyme Inhib Med Chem , 38 :2274797 , 2023 |
| Abstract : |
| PubMedSearch : Burmistrov_2023_J.Enzyme.Inhib.Med.Chem_38_2274797 |
| PubMedID: 37975322 |
| Title : Insect immune resolution with EpOME\/DiHOME and its dysregulation by their analogs leading to pathogen hypersensitivity - Hrithrik_2023_bioRxiv__ |
| Author(s) : Hrithrik MTH , Lee DH , Singh N , Vik A , Hammock BD , Kim Y |
| Ref : Biorxiv , : , 2023 |
| Abstract : |
| PubMedSearch : Hrithrik_2023_bioRxiv__ |
| PubMedID: 37461499 |
| Title : Eicosanoid profiles in an arthritis model: Effects of a soluble epoxide hydrolase inhibitor - Trindade-da-Silva_2023_Biochim.Biophys.Acta.Mol.Cell.Biol.Lipids_1869_159432 |
| Author(s) : Trindade-da-Silva CA , Yang J , Fonseca F , Pham H , Napimoga MH , Abdalla HB , Aver G , De Oliveira MJA , Hammock BD , Clemente-Napimoga JT |
| Ref : Biochimica & Biophysica Acta Molecular & Cellular Biology Lipids , 1869 :159432 , 2023 |
| Abstract : |
| PubMedSearch : Trindade-da-Silva_2023_Biochim.Biophys.Acta.Mol.Cell.Biol.Lipids_1869_159432 |
| PubMedID: 37984607 |
| Title : Neuroprotective effect of herbal extracts inhibiting soluble epoxide hydrolase (sEH) and cyclooxygenase (COX) against chemotherapy-induced cognitive impairment in mice - Kulkarni_2023_Biochem.Biophys.Res.Commun_667_64 |
| Author(s) : Kulkarni R , Mehta R , Goswami SK , Hammock BD , Morisseau C , Hwang SH , Mallappa O , Azeemuddin MM , Rafiq M , S NM |
| Ref : Biochemical & Biophysical Research Communications , 667 :64 , 2023 |
| Abstract : |
| PubMedSearch : Kulkarni_2023_Biochem.Biophys.Res.Commun_667_64 |
| PubMedID: 37209564 |
| Title : Direct targeting of sEH with alisol B alleviated the apoptosis, inflammation, and oxidative stress in cisplatin-induced acute kidney injury - Zhang_2023_Int.J.Biol.Sci_19_294 |
| Author(s) : Zhang J , Luan ZL , Huo XK , Zhang M , Morisseau C , Sun CP , Hammock BD , Ma XC |
| Ref : Int J Biol Sci , 19 :294 , 2023 |
| Abstract : |
| PubMedSearch : Zhang_2023_Int.J.Biol.Sci_19_294 |
| PubMedID: 36594097 |
| Title : COX-2\/sEH-mediated macrophage activation is a target for pulmonary protection in mouse models of chronic obstructive pulmonary disease - Duan_2023_Lab.Invest__100319 |
| Author(s) : Duan JX , Guan XX , Cheng W , Deng DD , Chen P , Liu C , Zhou Y , Hammock BD , Yang HH |
| Ref : Lab Invest , :100319 , 2023 |
| Abstract : |
| PubMedSearch : Duan_2023_Lab.Invest__100319 |
| PubMedID: 38158123 |
| Title : Hepatic Transcriptome and Its Regulation Following Soluble Epoxide Hydrolase Inhibition in Alcohol-Associated Liver Disease - Warner_2023_Am.J.Pathol__ |
| Author(s) : Warner JB , Hardesty JE , Song YL , Floyd AT , Deng Z , Jebet A , He L , Zhang X , McClain CJ , Hammock BD , Warner DR , Kirpich IA |
| Ref : American Journal of Pathology , : , 2023 |
| Abstract : |
| PubMedSearch : Warner_2023_Am.J.Pathol__ |
| PubMedID: 37925018 |
| Title : Aflatoxin B(1) Increases Soluble Epoxide Hydrolase in the Brain and Induces Neuroinflammation and Dopaminergic Neurotoxicity - Wang_2023_Int.J.Mol.Sci_24_9938 |
| Author(s) : Wang W , Wang Y , Wagner KM , Lee RD , Hwang SH , Morisseau C , Wulff H , Hammock BD |
| Ref : Int J Mol Sci , 24 :9938 , 2023 |
| Abstract : |
| PubMedSearch : Wang_2023_Int.J.Mol.Sci_24_9938 |
| PubMedID: 37373086 |
| Title : Inhibition of Soluble Epoxide Hydrolase Reduces Paraquat Neurotoxicity in Rodents - Atone_2023_Environ.Toxicol.Pharmacol__104070 |
| Author(s) : Atone J , Wagner K , Koike S , Yang J , Hwang SH , Hammock BD |
| Ref : Environ Toxicol Pharmacol , :104070 , 2023 |
| Abstract : |
| PubMedSearch : Atone_2023_Environ.Toxicol.Pharmacol__104070 |
| PubMedID: 36682504 |
| Title : Structure-Directed Discovery of Potent Soluble Epoxide Hydrolase Inhibitors for the Treatment of Inflammatory Diseases - Chen_2023_J.Med.Chem__ |
| Author(s) : Chen Y , Chen L , Xu H , Cao R , Morisseau C , Zhang M , Shi Y , Hammock BD , Wang J , Zhuang J , Liu Z , Chen G |
| Ref : Journal of Medicinal Chemistry , : , 2023 |
| Abstract : |
| PubMedSearch : Chen_2023_J.Med.Chem__ |
| PubMedID: 36689364 |
| Title : Screening and Biological Evaluation of Soluble Epoxide Hydrolase Inhibitors: Assessing the Role of Hydrophobicity in the Pharmacophore-Guided Search of Novel Hits - Vazquez_2023_J.Chem.Inf.Model__ |
| Author(s) : Vazquez J , Ginex T , Herrero A , Morisseau C , Hammock BD , Luque FJ |
| Ref : J Chem Inf Model , : , 2023 |
| Abstract : |
| PubMedSearch : Vazquez_2023_J.Chem.Inf.Model__ |
| PubMedID: 37141492 |
| Title : Modulating the sEH\/EETs Axis Restrains Specialized Proresolving Mediator Impairment and Regulates T Cell Imbalance in Experimental Periodontitis - Abdalla_2023_J.Immunol__ |
| Author(s) : Abdalla HB , Puhl L , Rivas CA , Wu YC , Rojas P , Trindade-da-Silva CA , Hammock BD , Maddipati KR , Soares MQS , Clemente-Napimoga JT , Kantarci A , Napimoga MH , Van Dyke TE |
| Ref : J Immunol , : , 2023 |
| Abstract : |
| PubMedSearch : Abdalla_2023_J.Immunol__ |
| PubMedID: 38117781 |
| Title : The Generation of a Nanobody-Based ELISA for Human Microsomal Epoxide Hydrolase - He_2023_Int.J.Mol.Sci_24_ |
| Author(s) : He Q , McCoy MR , Qi M , Morisseau C , Yang H , Xu C , Shey R , Goodman MC , Zhao S , Hammock BD |
| Ref : Int J Mol Sci , 24 : , 2023 |
| Abstract : |
| PubMedSearch : He_2023_Int.J.Mol.Sci_24_ |
| PubMedID: 37834144 |
| Title : Effects of chronic secondhand smoke exposure on cardiovascular regulation and the role of soluble epoxide hydrolase in mice - Pan_2023_Front.Physiol_14_1185744 |
| Author(s) : Pan S , Karey E , Nieves-Cintron M , Chen YJ , Hwang SH , Hammock BD , Pinkerton KE , Chen CY |
| Ref : Front Physiol , 14 :1185744 , 2023 |
| Abstract : |
| PubMedSearch : Pan_2023_Front.Physiol_14_1185744 |
| PubMedID: 37362438 |
| Title : Mix-and-Read Nanobody-Based Sandwich Homogeneous Split-Luciferase Assay for the Rapid Detection of Human Soluble Epoxide Hydrolase - He_2023_Anal.Chem__ |
| Author(s) : He Q , McCoy MR , Yang H , Lin M , Cui X , Zhao S , Morisseau C , Li D , Hammock BD |
| Ref : Analytical Chemistry , : , 2023 |
| Abstract : |
| PubMedSearch : He_2023_Anal.Chem__ |
| PubMedID: 36972550 |
| Title : Hepatocyte-specific disruption of soluble epoxide hydrolase attenuates abdominal aortic aneurysm formation: novel role of the liver in aneurysm pathogenesis - Kim_2023_bioRxiv__ |
| Author(s) : Kim D , Horimatsu T , Ogbi M , Goo B , Shi H , Veerapaneni P , Chouhaita R , Moses M , Prasad R , Benson TW , Harb R , Aboud G , Seller H , Haigh S , Fulton DJ , Csanyi G , Huo Y , Long X , Coffey P , Lee R , Guha A , Zeldin D , Hwang SH , Hammock BD , Weintraub NL , Kim HW |
| Ref : Biorxiv , : , 2023 |
| Abstract : |
| PubMedSearch : Kim_2023_bioRxiv__ |
| PubMedID: 37503031 |
| Title : Soluble epoxide hydrolase inhibition alleviates chemotherapy induced neuropathic pain - Takeshita_2022_Front.Pain.Res.(Lausanne)_3_1100524 |
| Author(s) : Takeshita AA , Hammock BD , Wagner KM |
| Ref : Front Pain Res (Lausanne) , 3 :1100524 , 2022 |
| Abstract : |
| PubMedSearch : Takeshita_2022_Front.Pain.Res.(Lausanne)_3_1100524 |
| PubMedID: 36700145 |
| Title : Synthesis, In Vitro Profiling, and In Vivo Evaluation of Benzohomoadamantane-Based Ureas for Visceral Pain: A New Indication for Soluble Epoxide Hydrolase Inhibitors - Codony_2022_J.Med.Chem_65_13660 |
| Author(s) : Codony S , Entrena JM , Calvo-Tusell C , Jora B , Gonzalez-Cano R , Osuna S , Corpas R , Morisseau C , Perez B , Barniol-Xicota M , Grinan-Ferre C , Perez C , Rodriguez-Franco MI , Martinez AL , Loza MI , Pallas M , Verhelst SHL , Sanfeliu C , Feixas F , Hammock BD , Brea J , Cobos EJ , Vazquez S |
| Ref : Journal of Medicinal Chemistry , 65 :13660 , 2022 |
| Abstract : |
| PubMedSearch : Codony_2022_J.Med.Chem_65_13660 |
| PubMedID: 36222708 |
| Title : Structure-activity relationship studies of benzothiazole-phenyl analogs as multi-target ligands to alleviate pain without affecting normal behavior - Angelia_2022_Prostaglandins.Other.Lipid.Mediat__106702 |
| Author(s) : Angelia J , Weng X , Solomatov A , Chin C , Fernandez A , Hudson PK , Morisseau C , Hammock BD , Kandasamy R , Pecic S |
| Ref : Prostaglandins Other Lipid Mediat , :106702 , 2022 |
| Abstract : |
| PubMedSearch : Angelia_2022_Prostaglandins.Other.Lipid.Mediat__106702 |
| PubMedID: 36529320 |
| Title : Soluble epoxide hydrolase inhibition avoid formalin-induced inflammatory hyperalgesia in the temporomandibular joint - Abdalla_2022_Inflammopharmacology__ |
| Author(s) : Abdalla HB , Napimoga MH , Teixeira JM , Trindade-da-Silva CA , Pieroni VL , Dos Santos Araujo FSM , Hammock BD , Clemente-Napimoga JT |
| Ref : Inflammopharmacology , : , 2022 |
| Abstract : |
| PubMedSearch : Abdalla_2022_Inflammopharmacology__ |
| PubMedID: 35303234 |
| Title : Novel aerosol treatment of airway hyper-reactivity and inflammation in a murine model of asthma with a soluble epoxide hydrolase inhibitor - Zhang_2022_PLoS.One_17_e0266608 |
| Author(s) : Zhang C , Li W , Li X , Wan D , Mack S , Zhang J , Wagner K , Wang C , Tan B , Chen J , Wu CW , Tsuji K , Takeuchi M , Chen Z , Hammock BD , Pinkerton KE , Yang J |
| Ref : PLoS ONE , 17 :e0266608 , 2022 |
| Abstract : |
| PubMedSearch : Zhang_2022_PLoS.One_17_e0266608 |
| PubMedID: 35443010 |
| Title : sEH-derived metabolites of linoleic acid drive pathologic inflammation while impairing key innate immune cell function in burn injury - Bergmann_2022_Proc.Natl.Acad.Sci.U.S.A_119_e2120691119 |
| Author(s) : Bergmann CB , McReynolds CB , Wan D , Singh N , Goetzman H , Caldwell CC , Supp DM , Hammock BD |
| Ref : Proc Natl Acad Sci U S A , 119 :e2120691119 , 2022 |
| Abstract : |
| PubMedSearch : Bergmann_2022_Proc.Natl.Acad.Sci.U.S.A_119_e2120691119 |
| PubMedID: 35312372 |
| Title : Structure-guided discovery of potent and oral soluble epoxide hydrolase inhibitors for the treatment of neuropathic pain - Du_2022_Acta.Pharm.Sin.B_12_1377 |
| Author(s) : Du F , Cao R , Chen L , Sun J , Shi Y , Fu Y , Hammock BD , Zheng Z , Liu Z , Chen G |
| Ref : Acta Pharm Sin B , 12 :1377 , 2022 |
| Abstract : |
| PubMedSearch : Du_2022_Acta.Pharm.Sin.B_12_1377 |
| PubMedID: 35530144 |
| Title : Soluble Epoxide Hydrolase Is Associated with Postprandial Anxiety Decrease in Healthy Adult Women - Nguyen_2022_Int.J.Mol.Sci_23_ |
| Author(s) : Nguyen N , Morisseau C , Li D , Yang J , Lam E , Woodside DB , Hammock BD , Shih PB |
| Ref : Int J Mol Sci , 23 : , 2022 |
| Abstract : |
| PubMedSearch : Nguyen_2022_Int.J.Mol.Sci_23_ |
| PubMedID: 36233100 |
| Title : Kurarinone alleviated Parkinson's disease via stabilization of epoxyeicosatrienoic acids in animal model - Sun_2022_Proc.Natl.Acad.Sci.U.S.A_119_ |
| Author(s) : Sun CP , Zhou JJ , Yu ZL , Huo XK , Zhang J , Morisseau C , Hammock BD , Ma XC |
| Ref : Proc Natl Acad Sci U S A , 119 : , 2022 |
| Abstract : |
| PubMedSearch : Sun_2022_Proc.Natl.Acad.Sci.U.S.A_119_ |
| PubMedID: 35217618 |
| Gene_locus related to this paper: human-EPHX2 |
| Title : Soluble epoxide hydrolase inhibition enhances Specialized Pro-resolving Lipid Mediator production and promotes macrophage plasticity - Abdalla_2022_Br.J.Pharmacol__ |
| Author(s) : Abdalla HB , Alvarez C , Wu YC , Rojas P , Hammock BD , Maddipati KR , Trindade-da-Silva CA , Soares MQS , Clemente-Napimoga JT , Kantarci A , Napimoga MH , Van Dyke TE |
| Ref : British Journal of Pharmacology , : , 2022 |
| Abstract : |
| PubMedSearch : Abdalla_2022_Br.J.Pharmacol__ |
| PubMedID: 36508312 |
| Title : Aflatoxin B(1) exposure disrupts the intestinal immune function via a soluble epoxide hydrolase-mediated manner - Wang_2022_Ecotoxicol.Environ.Saf_249_114417 |
| Author(s) : Wang W , Wang Y , Yang J , Wagner KM , Hwang SH , Cheng J , Singh N , Edwards P , Morisseau C , Zhang G , Panigrahy D , Hammock BD |
| Ref : Ecotoxicology & Environmental Safety , 249 :114417 , 2022 |
| Abstract : |
| PubMedSearch : Wang_2022_Ecotoxicol.Environ.Saf_249_114417 |
| PubMedID: 36525946 |
| Title : Role of the soluble epoxide hydrolase in the hair follicle stem cell homeostasis and hair growth - Naeem_2022_Pflugers.Arch__ |
| Author(s) : Naeem Z , Zukunft S , Gunther S , Liebner S , Weigert A , Hammock BD , Fromel T , Fleming I |
| Ref : Pflugers Arch , : , 2022 |
| Abstract : |
| PubMedSearch : Naeem_2022_Pflugers.Arch__ |
| PubMedID: 35648219 |
| Title : Anti-Inflammatory Activity of Soluble Epoxide Hydrolase Inhibitors Based on Selenoureas Bearing an Adamantane Moiety - Burmistrov_2022_Int.J.Mol.Sci_23_ |
| Author(s) : Burmistrov V , Morisseau C , Babkov DA , Golubeva T , Pitushkin D , Sokolova EV , Vasipov V , Kuznetsov Y , Bazhenov SV , Novoyatlova US , Bondarev NA , Manukhov IV , Osipova V , Berberova N , Spasov AA , Butov GM , Hammock BD |
| Ref : Int J Mol Sci , 23 : , 2022 |
| Abstract : |
| PubMedSearch : Burmistrov_2022_Int.J.Mol.Sci_23_ |
| PubMedID: 36142611 |
| Title : Discovery and In Vivo Proof of Concept of a Highly Potent Dual Inhibitor of Soluble Epoxide Hydrolase and Acetylcholinesterase for the Treatment of Alzheimer's Disease - Codony_2022_J.Med.Chem_65_4909 |
| Author(s) : Codony S , Pont C , Grinan-Ferre C , Di Pede-Mattatelli A , Calvo-Tusell C , Feixas F , Osuna S , Jarne-Ferrer J , Naldi M , Bartolini M , Loza MI , Brea J , Perez B , Bartra C , Sanfeliu C , Juarez-Jimenez J , Morisseau C , Hammock BD , Pallas M , Vazquez S , Munoz-Torrero D |
| Ref : Journal of Medicinal Chemistry , 65 :4909 , 2022 |
| Abstract : |
| PubMedSearch : Codony_2022_J.Med.Chem_65_4909 |
| PubMedID: 35271276 |
| Title : Differential Effects of 17,18-EEQ and 19,20-EDP Combined with Soluble Epoxide Hydrolase Inhibitor t-TUCB on Diet-Induced Obesity in Mice - Yang_2021_Int.J.Mol.Sci_22_ |
| Author(s) : Yang Y , Xu X , Wu H , Yang J , Chen J , Morisseau C , Hammock BD , Bettaieb A , Zhao L |
| Ref : Int J Mol Sci , 22 : , 2021 |
| Abstract : |
| PubMedSearch : Yang_2021_Int.J.Mol.Sci_22_ |
| PubMedID: 34361032 |
| Title : Inhibition of the Soluble Epoxide Hydrolase as an Analgesic Strategy: A Review of Preclinical Evidence - Wang_2021_J.Pain.Res_14_61 |
| Author(s) : Wang Y , Wagner KM , Morisseau C , Hammock BD |
| Ref : J Pain Res , 14 :61 , 2021 |
| Abstract : |
| PubMedSearch : Wang_2021_J.Pain.Res_14_61 |
| PubMedID: 33488116 |
| Title : Ibuprofen alters epoxide hydrolase activity and epoxy-oxylipin metabolites associated with different metabolic pathways in murine livers - Tiwari_2021_Sci.Rep_11_7042 |
| Author(s) : Tiwari S , Yang J , Morisseau C , Durbin-Johnson B , Hammock BD , Gomes AV |
| Ref : Sci Rep , 11 :7042 , 2021 |
| Abstract : |
| PubMedSearch : Tiwari_2021_Sci.Rep_11_7042 |
| PubMedID: 33782432 |
| Title : Further exploration of the structure-activity relationship of dual soluble epoxide hydrolase\/fatty acid amide hydrolase inhibitors - Wilt_2021_Bioorg.Med.Chem_51_116507 |
| Author(s) : Wilt S , Kodani S , Valencia L , Hudson PK , Sanchez S , Quintana T , Morisseau C , Hammock BD , Kandasamy R , Pecic S |
| Ref : Bioorganic & Medicinal Chemistry , 51 :116507 , 2021 |
| Abstract : |
| PubMedSearch : Wilt_2021_Bioorg.Med.Chem_51_116507 |
| PubMedID: 34794001 |
| Title : Role of epoxide hydrolases and cytochrome P450s on metabolism of KZR-616, a first-in-class selective inhibitor of the immunoproteasome - Fang_2021_Drug.Metab.Dispos__ |
| Author(s) : Fang Y , Johnson H , Anderl JL , Muchamuel T , McMinn D , Morisseau C , Hammock BD , Kirk C , Wang J |
| Ref : Drug Metabolism & Disposition: The Biological Fate of Chemicals , : , 2021 |
| Abstract : |
| PubMedSearch : Fang_2021_Drug.Metab.Dispos__ |
| PubMedID: 34234005 |
| Gene_locus related to this paper: human-EPHX1 |
| Title : Inhibition of sEH via stabilizing the level of EETs alleviated Alzheimer's disease through GSK3beta signaling pathway - Sun_2021_Food.Chem.Toxicol_156_112516 |
| Author(s) : Sun CP , Zhang XY , Zhou JJ , Huo XK , Yu ZL , Morisseau C , Hammock BD , Ma XC |
| Ref : Food & Chemical Toxicology , 156 :112516 , 2021 |
| Abstract : |
| PubMedSearch : Sun_2021_Food.Chem.Toxicol_156_112516 |
| PubMedID: 34411643 |
| Title : TPPU treatment of burned mice dampens inflammation and generation of bioactive DHET which impairs neutrophil function - Bergmann_2021_Sci.Rep_11_16555 |
| Author(s) : Bergmann CB , Hammock BD , Wan D , Gogolla F , Goetzman H , Caldwell CC , Supp DM |
| Ref : Sci Rep , 11 :16555 , 2021 |
| Abstract : |
| PubMedSearch : Bergmann_2021_Sci.Rep_11_16555 |
| PubMedID: 34400718 |
| Title : Activity of sEH and Oxidant Status during Systemic Bovine Coliform Mastitis - Mavangira_2021_Antioxidants.(Basel)_10_ |
| Author(s) : Mavangira V , Kuhn MJ , Abuelo A , Morisseau C , Hammock BD , Sordillo LM |
| Ref : Antioxidants (Basel) , 10 : , 2021 |
| Abstract : |
| PubMedSearch : Mavangira_2021_Antioxidants.(Basel)_10_ |
| PubMedID: 34065244 |
| Title : Relative Importance of Soluble and Microsomal Epoxide Hydrolases for the Hydrolysis of Epoxy-Fatty Acids in Human Tissues - Morisseau_2021_Int.J.Mol.Sci_22_ |
| Author(s) : Morisseau C , Kodani SD , Kamita SG , Yang J , Lee KSS , Hammock BD |
| Ref : Int J Mol Sci , 22 : , 2021 |
| Abstract : |
| PubMedSearch : Morisseau_2021_Int.J.Mol.Sci_22_ |
| PubMedID: 34066758 |
| Title : Dual sEH\/COX-2 Inhibition Using PTUPB-A Promising Approach to Antiangiogenesis-Induced Nephrotoxicity - Jankiewicz_2021_Front.Pharmacol_12_744776 |
| Author(s) : Jankiewicz WK , Barnett SD , Stavniichuk A , Hwang SH , Hammock BD , Belayet JB , Khan AH , Imig JD |
| Ref : Front Pharmacol , 12 :744776 , 2021 |
| Abstract : |
| PubMedSearch : Jankiewicz_2021_Front.Pharmacol_12_744776 |
| PubMedID: 34955823 |
| Title : Soluble Epoxide Hydrolase Deletion Limits High-Fat Diet-Induced Inflammation - Wagner_2021_Front.Pharmacol_12_778470 |
| Author(s) : Wagner KM , Yang J , Morisseau C , Hammock BD |
| Ref : Front Pharmacol , 12 :778470 , 2021 |
| Abstract : |
| PubMedSearch : Wagner_2021_Front.Pharmacol_12_778470 |
| PubMedID: 34975481 |
| Gene_locus related to this paper: mouse-hyes |
| Title : Adrenic Acid-Derived Epoxy Fatty Acids Are Naturally Occurring Lipids and Their Methyl Ester Prodrug Reduces Endoplasmic Reticulum Stress and Inflammatory Pain - Singh_2021_ACS.Omega_6_7165 |
| Author(s) : Singh N , Barnych B , Wagner KM , Wan D , Morisseau C , Hammock BD |
| Ref : ACS Omega , 6 :7165 , 2021 |
| Abstract : |
| PubMedSearch : Singh_2021_ACS.Omega_6_7165 |
| PubMedID: 33748630 |
| Title : Multitarget molecule,PTUPB, to treat diabetic nephropathy in rats - Hye_2021_Br.J.Pharmacol_178_4468 |
| Author(s) : Hye Khan MA , Hwang SH , Barnett SD , Stavniichuk A , Jankiewicz WK , Hammock BD , Imig JD |
| Ref : British Journal of Pharmacology , 178 :4468 , 2021 |
| Abstract : |
| PubMedSearch : Hye_2021_Br.J.Pharmacol_178_4468 |
| PubMedID: 34255857 |
| Title : Soluble Epoxide Hydrolase in Aged Female Mice and Human Explanted Hearts Following Ischemic Injury - Jamieson_2021_Int.J.Mol.Sci_22_ |
| Author(s) : Jamieson KL , Darwesh AM , Sosnowski DK , Zhang H , Shah S , Zhabyeyev P , Yang J , Hammock BD , Edin ML , Zeldin DC , Oudit GY , Kassiri Z , Seubert JM |
| Ref : Int J Mol Sci , 22 : , 2021 |
| Abstract : |
| PubMedSearch : Jamieson_2021_Int.J.Mol.Sci_22_ |
| PubMedID: 33567578 |
| Title : COX-2\/sEH Dual Inhibitor PTUPB Alleviates CCl (4) -Induced Liver Fibrosis and Portal Hypertension - Zhao_2021_Front.Med.(Lausanne)_8_761517 |
| Author(s) : Zhao Z , Zhang C , Lin J , Zheng L , Li H , Qi X , Huo H , Lou X , Hammock BD , Hwang SH , Bao Y , Luo M |
| Ref : Front Med (Lausanne) , 8 :761517 , 2021 |
| Abstract : |
| PubMedSearch : Zhao_2021_Front.Med.(Lausanne)_8_761517 |
| PubMedID: 35004731 |
| Title : Discovery of memantyl urea derivatives as potent soluble epoxide hydrolase inhibitors against lipopolysaccharide-induced sepsis - Du_2021_Eur.J.Med.Chem_223_113678 |
| Author(s) : Du F , Sun W , Morisseau C , Hammock BD , Bao X , Liu Q , Wang C , Zhang T , Yang H , Zhou J , Xiao W , Liu Z , Chen G |
| Ref : Eur Journal of Medicinal Chemistry , 223 :113678 , 2021 |
| Abstract : |
| PubMedSearch : Du_2021_Eur.J.Med.Chem_223_113678 |
| PubMedID: 34218083 |
| Title : Discovery of Soluble Epoxide Hydrolase Inhibitors from Chemical Synthesis and Natural Products - Sun_2021_J.Med.Chem_64_184 |
| Author(s) : Sun CP , Zhang XY , Morisseau C , Hwang SH , Zhang ZJ , Hammock BD , Ma XC |
| Ref : Journal of Medicinal Chemistry , 64 :184 , 2021 |
| Abstract : |
| PubMedSearch : Sun_2021_J.Med.Chem_64_184 |
| PubMedID: 33369424 |
| Title : Movement to the Clinic of Soluble Epoxide Hydrolase Inhibitor EC5026 as an Analgesic for Neuropathic Pain and for Use as a Nonaddictive Opioid Alternative - Hammock_2021_J.Med.Chem__ |
| Author(s) : Hammock BD , McReynolds CB , Wagner K , Buckpitt A , Cortes-Puch I , Croston G , Lee KSS , Yang J , Schmidt WK , Hwang SH |
| Ref : Journal of Medicinal Chemistry , : , 2021 |
| Abstract : |
| PubMedSearch : Hammock_2021_J.Med.Chem__ |
| PubMedID: 33550801 |
| Title : Ingestion of Faecalibaculum rodentium causes depression-like phenotypes in resilient Ephx2 knock-out mice: A role of brain-gut-microbiota axis via the subdiaphragmatic vagus nerve - Wang_2021_J.Affect.Disord_292_565 |
| Author(s) : Wang S , Ishima T , Qu Y , Shan J , Chang L , Wei Y , Zhang J , Pu Y , Fujita Y , Tan Y , Wang X , Ma L , Wan X , Hammock BD , Hashimoto K |
| Ref : J Affect Disord , 292 :565 , 2021 |
| Abstract : |
| PubMedSearch : Wang_2021_J.Affect.Disord_292_565 |
| PubMedID: 34147969 |
| Title : From the Design to the In Vivo Evaluation of Benzohomoadamantane-Derived Soluble Epoxide Hydrolase Inhibitors for the Treatment of Acute Pancreatitis - Codony_2021_J.Med.Chem__ |
| Author(s) : Codony S , Calvo-Tusell C , Valverde E , Osuna S , Morisseau C , Loza MI , Brea J , Perez C , Rodriguez-Franco MI , Pizarro-Delgado J , Corpas R , Grinan-Ferre C , Pallas M , Sanfeliu C , Vazquez-Carrera M , Hammock BD , Feixas F , Vazquez S |
| Ref : Journal of Medicinal Chemistry , : , 2021 |
| Abstract : |
| PubMedSearch : Codony_2021_J.Med.Chem__ |
| PubMedID: 33945278 |
| Title : New Alkoxy- Analogues of Epoxyeicosatrienoic Acids Attenuate Cisplatin Nephrotoxicity In Vitro via Reduction of Mitochondrial Dysfunction, Oxidative Stress, Mitogen-Activated Protein Kinase Signaling, and Caspase Activation - Singh_2021_Chem.Res.Toxicol__ |
| Author(s) : Singh N , Vik A , Lybrand DB , Morisseau C , Hammock BD |
| Ref : Chemical Research in Toxicology , : , 2021 |
| Abstract : |
| PubMedSearch : Singh_2021_Chem.Res.Toxicol__ |
| PubMedID: 34817988 |
| Title : Genetic deficiency or pharmacological inhibition of soluble epoxide hydrolase ameliorates high fat diet-induced pancreatic beta-cell dysfunction and loss - Koike_2021_Free.Radic.Biol.Med__ |
| Author(s) : Koike S , Hsu MF , Bettaieb A , Chu B , Matsumoto N , Morisseau C , Havel PJ , Huising MO , Hammock BD , Haj FG |
| Ref : Free Radic Biol Med , : , 2021 |
| Abstract : |
| PubMedSearch : Koike_2021_Free.Radic.Biol.Med__ |
| PubMedID: 34038767 |
| Title : A Soluble Epoxide Hydrolase Inhibitor, 1-TrifluoromethoxyPhenyl-3-(1-Propionylpiperidin-4-yl) Urea, Ameliorates Experimental Autoimmune Encephalomyelitis - Jonnalagadda_2021_Int.J.Mol.Sci_22_ |
| Author(s) : Jonnalagadda D , Wan D , Chun J , Hammock BD , Kihara Y |
| Ref : Int J Mol Sci , 22 : , 2021 |
| Abstract : |
| PubMedSearch : Jonnalagadda_2021_Int.J.Mol.Sci_22_ |
| PubMedID: 33925035 |
| Title : 2-(Piperidin-4-yl)acetamides as Potent Inhibitors of Soluble Epoxide Hydrolase with Anti-Inflammatory Activity - Martin-Lopez_2021_Pharmaceuticals.(Basel)_14_ |
| Author(s) : Martin-Lopez J , Codony S , Bartra C , Morisseau C , Loza MI , Sanfeliu C , Hammock BD , Brea J , Vazquez S |
| Ref : Pharmaceuticals (Basel) , 14 : , 2021 |
| Abstract : |
| PubMedSearch : Martin-Lopez_2021_Pharmaceuticals.(Basel)_14_ |
| PubMedID: 34959721 |
| Title : EPHX1 mutations cause a lipoatrophic diabetes syndrome due to impaired epoxide hydrolysis and increased cellular senescence - Gautheron_2021_Elife_10_ |
| Author(s) : Gautheron J , Morisseau C , Chung WK , Zammouri J , Auclair M , Baujat G , Capel E , Moulin C , Wang Y , Yang J , Hammock BD , Cerame B , Phan F , Feve B , Vigouroux C , Andreelli F , Jeru I |
| Ref : Elife , 10 : , 2021 |
| Abstract : |
| PubMedSearch : Gautheron_2021_Elife_10_ |
| PubMedID: 34342583 |
| Gene_locus related to this paper: human-EPHX1 |
| Title : Plasma Linoleate Diols Are Potential Biomarkers for Severe COVID-19 Infections - McReynolds_2021_Front.Physiol_12_663869 |
| Author(s) : McReynolds CB , Cortes-Puch I , Ravindran R , Khan IH , Hammock BG , Shih PB , Hammock BD , Yang J |
| Ref : Front Physiol , 12 :663869 , 2021 |
| Abstract : |
| PubMedSearch : McReynolds_2021_Front.Physiol_12_663869 |
| PubMedID: 33868029 |
| Title : Species Differences in Metabolism of Soluble Epoxide Hydrolase Inhibitor, EC1728, Highlight the Importance of Clinically Relevant Screening Mechanisms in Drug Development - McReynolds_2021_Molecules_26_ |
| Author(s) : McReynolds CB , Yang J , Guedes A , Morisseau C , Garcia R , Knych H , Tearney C , Hamamoto B , Hwang SH , Wagner K , Hammock BD |
| Ref : Molecules , 26 : , 2021 |
| Abstract : |
| PubMedSearch : McReynolds_2021_Molecules_26_ |
| PubMedID: 34443621 |
| Title : Soluble Epoxide Hydrolase Hepatic Deficiency Ameliorates Alcohol-Associated Liver Disease - Mello_2021_Cell.Mol.Gastroenterol.Hepatol_11_815 |
| Author(s) : Mello A , Hsu MF , Koike S , Chu B , Cheng J , Yang J , Morisseau C , Torok NJ , Hammock BD , Haj FG |
| Ref : Cell Mol Gastroenterol Hepatol , 11 :815 , 2021 |
| Abstract : |
| PubMedSearch : Mello_2021_Cell.Mol.Gastroenterol.Hepatol_11_815 |
| PubMedID: 33068774 |
| Title : Target-Mediated Drug Disposition-A Class Effect of Soluble Epoxide Hydrolase Inhibitors - An_2021_J.Clin.Pharmacol_61_531 |
| Author(s) : An G , Lee KSS , Yang J , Hammock BD |
| Ref : Journal of Clinical Pharmacology , 61 :531 , 2021 |
| Abstract : |
| PubMedSearch : An_2021_J.Clin.Pharmacol_61_531 |
| PubMedID: 33078430 |
| Title : Pharmacological Inhibition of Soluble Epoxide Hydrolase as a New Therapy for Alzheimer's Disease - Grinan-Ferre_2020_Neurotherapeutics__ |
| Author(s) : Grinan-Ferre C , Codony S , Pujol E , Yang J , Leiva R , Escolano C , Puigoriol-Illamola D , Companys-Alemany J , Corpas R , Sanfeliu C , Perez B , Loza MI , Brea J , Morisseau C , Hammock BD , Vazquez S , Pallas M , Galdeano C |
| Ref : Neurotherapeutics , : , 2020 |
| Abstract : |
| PubMedSearch : Grinan-Ferre_2020_Neurotherapeutics__ |
| PubMedID: 32488482 |
| Title : Preparation and evaluation of soluble epoxide hydrolase inhibitors with improved physical properties and potencies for treating diabetic neuropathic pain - Lee_2020_Bioorg.Med.Chem_28_115735 |
| Author(s) : Lee KSS , Ng JC , Yang J , Hwang SH , Morisseau C , Wagner K , Hammock BD |
| Ref : Bioorganic & Medicinal Chemistry , 28 :115735 , 2020 |
| Abstract : |
| PubMedSearch : Lee_2020_Bioorg.Med.Chem_28_115735 |
| PubMedID: 33007552 |
| Title : Soluble Epoxide Hydrolase Inhibition Improves Cognitive Function and Parenchymal Artery Dilation in a Hypertensive Model of Chronic Cerebral Hypoperfusion - Matin_2020_Microcirculation__e12653 |
| Author(s) : Matin N , Fisher C , Lansdell TA , Hammock BD , Yang J , Jackson WF , Dorrance AM |
| Ref : Microcirculation , :e12653 , 2020 |
| Abstract : |
| PubMedSearch : Matin_2020_Microcirculation__e12653 |
| PubMedID: 32767848 |
| Title : Increased expression of soluble epoxide hydrolase in the brain and liver from patients with major psychiatric disorders: A role of brain - liver axis - Zhang_2020_J.Affect.Disord_270_131 |
| Author(s) : Zhang J , Tan Y , Chang L , Hammock BD , Hashimoto K |
| Ref : J Affect Disord , 270 :131 , 2020 |
| Abstract : |
| PubMedSearch : Zhang_2020_J.Affect.Disord_270_131 |
| PubMedID: 32339103 |
| Title : Vascular Lipidomic Profiling of Potential Endogenous Fatty Acid PPAR Ligands Reveals the Coronary Artery as Major Producer of CYP450-Derived Epoxy Fatty Acids - Edin_2020_Cells_9_ |
| Author(s) : Edin ML , Lih FB , Hammock BD , Thomson S , Zeldin DC , Bishop-Bailey D |
| Ref : Cells , 9 : , 2020 |
| Abstract : |
| PubMedSearch : Edin_2020_Cells_9_ |
| PubMedID: 32365470 |
| Title : Protostane-type triterpenoids as natural soluble epoxide hydrolase inhibitors: Inhibition potentials and molecular dynamics - Sun_2020_Bioorg.Chem_96_103637 |
| Author(s) : Sun CP , Zhang J , Zhao WY , Yi J , Yan JK , Wang YL , Morisseau C , Liu ZB , Hammock BD , Ma XC |
| Ref : Bioorg Chem , 96 :103637 , 2020 |
| Abstract : |
| PubMedSearch : Sun_2020_Bioorg.Chem_96_103637 |
| PubMedID: 32032849 |
| Title : Development of potent inhibitors of the human microsomal epoxide hydrolase - Barnych_2020_Eur.J.Med.Chem_193_112206 |
| Author(s) : Barnych B , Singh N , Negrel S , Zhang Y , Magis D , Roux C , Hua X , Ding Z , Morisseau C , Tantillo DJ , Siegel JB , Hammock BD |
| Ref : Eur Journal of Medicinal Chemistry , 193 :112206 , 2020 |
| Abstract : |
| PubMedSearch : Barnych_2020_Eur.J.Med.Chem_193_112206 |
| PubMedID: 32203787 |
| Gene_locus related to this paper: human-EPHX1 , mouse-EPHX1 |
| Title : Assessment of Soluble Epoxide Hydrolase Activity In Vivo: A Metabolomic Approach - Stefanovski_2020_Prostaglandins.Other.Lipid.Mediat__106410 |
| Author(s) : Stefanovski D , Shih PB , Hammock BD , Watanabe RM , Youn JH |
| Ref : Prostaglandins Other Lipid Mediat , :106410 , 2020 |
| Abstract : |
| PubMedSearch : Stefanovski_2020_Prostaglandins.Other.Lipid.Mediat__106410 |
| PubMedID: 31931080 |
| Title : Maternal glyphosate exposure causes autism-like behaviors in offspring through increased expression of soluble epoxide hydrolase - Pu_2020_Proc.Natl.Acad.Sci.U.S.A__ |
| Author(s) : Pu Y , Yang J , Chang L , Qu Y , Wang S , Zhang K , Xiong Z , Zhang J , Tan Y , Wang X , Fujita Y , Ishima T , Wan D , Hwang SH , Hammock BD , Hashimoto K |
| Ref : Proc Natl Acad Sci U S A , : , 2020 |
| Abstract : |
| PubMedSearch : Pu_2020_Proc.Natl.Acad.Sci.U.S.A__ |
| PubMedID: 32398374 |
| Title : Soluble epoxide hydrolase inhibitor mediated analgesia lacks tolerance in rat models - Wagner_2020_Brain.Res_1728_146573 |
| Author(s) : Wagner KM , Atone J , Hammock BD |
| Ref : Brain Research , 1728 :146573 , 2020 |
| Abstract : |
| PubMedSearch : Wagner_2020_Brain.Res_1728_146573 |
| PubMedID: 31790682 |
| Title : An epoxide hydrolase inhibitor reduces neuroinflammation in a mouse model of Alzheimer's disease - Ghosh_2020_Sci.Transl.Med_12_ |
| Author(s) : Ghosh A , Comerota MM , Wan D , Chen F , Propson NE , Hwang SH , Hammock BD , Zheng H |
| Ref : Sci Transl Med , 12 : , 2020 |
| Abstract : |
| PubMedSearch : Ghosh_2020_Sci.Transl.Med_12_ |
| PubMedID: 33298560 |
| Title : Soluble epoxide hydrolase inhibitor, TPPU, increases regulatory T cells pathway in an arthritis model - Trindade-da-Silva_2020_FASEB.J__ |
| Author(s) : Trindade-da-Silva CA , Clemente-Napimoga JT , Abdalla HB , Rosa SM , Ueira-Vieira C , Morisseau C , Verri WA, Jr. , Montalli VAM , Hammock BD , Napimoga MH |
| Ref : FASEB Journal , : , 2020 |
| Abstract : |
| PubMedSearch : Trindade-da-Silva_2020_FASEB.J__ |
| PubMedID: 32400048 |
| Title : 1-trifluoromethoxyphenyl-3-(1-propionylpiperidin-4-yl) urea (TPPU), a soluble epoxide hydrolase inhibitor, lowers L-NAME-induced hypertension through suppression of angiotensin-converting enzyme in rats - Bukhari_2020_Eur.Rev.Med.Pharmacol.Sci_24_8143 |
| Author(s) : Bukhari IA , Alorainey BI , Al-Motrefi AA , Mahmoud A , Campbell WB , Hammock BD |
| Ref : Eur Rev Med Pharmacol Sci , 24 :8143 , 2020 |
| Abstract : |
| PubMedSearch : Bukhari_2020_Eur.Rev.Med.Pharmacol.Sci_24_8143 |
| PubMedID: 32767352 |
| Title : Selection of Potent Inhibitors of Soluble Epoxide Hydrolase for Usage in Veterinary Medicine - Shihadih_2020_Front.Vet.Sci_7_580 |
| Author(s) : Shihadih DS , Harris TR , Kodani SD , Hwang SH , Lee KSS , Mavangira V , Hamamoto B , Guedes A , Hammock BD , Morisseau C |
| Ref : Front Vet Sci , 7 :580 , 2020 |
| Abstract : |
| PubMedSearch : Shihadih_2020_Front.Vet.Sci_7_580 |
| PubMedID: 33005645 |
| Title : PTUPB ameliorates high-fat diet-induced non-alcoholic fatty liver disease via inhibiting NLRP3 inflammasome activation in mice - Sun_2020_Biochem.Biophys.Res.Commun__ |
| Author(s) : Sun CC , Zhang CY , Duan JX , Guan XX , Yang HH , Jiang HL , Hammock BD , Hwang SH , Zhou Y , Guan CX , Liu SK , Zhang J |
| Ref : Biochemical & Biophysical Research Communications , : , 2020 |
| Abstract : |
| PubMedSearch : Sun_2020_Biochem.Biophys.Res.Commun__ |
| PubMedID: 31973813 |
| Title : Soluble Epoxide Hydrolase Regulation of Lipid Mediators Limits Pain - Wagner_2020_Neurotherapeutics_17_900 |
| Author(s) : Wagner KM , Gomes A , McReynolds CB , Hammock BD |
| Ref : Neurotherapeutics , 17 :900 , 2020 |
| Abstract : |
| PubMedSearch : Wagner_2020_Neurotherapeutics_17_900 |
| PubMedID: 32875445 |
| Title : A COX-2\/sEH dual inhibitor PTUPB alleviates lipopolysaccharide-induced acute lung injury in mice by inhibiting NLRP3 inflammasome activation - Yang_2020_Theranostics_10_4749 |
| Author(s) : Yang HH , Duan JX , Liu SK , Xiong JB , Guan XX , Zhong WJ , Sun CC , Zhang CY , Luo XQ , Zhang YF , Chen P , Hammock BD , Hwang SH , Jiang JX , Zhou Y , Guan CX |
| Ref : Theranostics , 10 :4749 , 2020 |
| Abstract : |
| PubMedSearch : Yang_2020_Theranostics_10_4749 |
| PubMedID: 32308747 |
| Title : A COX-2\/sEH dual inhibitor PTUPB ameliorates cecal ligation and puncture-induced sepsis in mice via anti-inflammation and anti-oxidative stress - Zhang_2020_Biomed.Pharmacother_126_109907 |
| Author(s) : Zhang YF , Sun CC , Duan JX , Yang HH , Zhang CY , Xiong JB , Zhong WJ , Zu C , Guan XX , Jiang HL , Hammock BD , Hwang SH , Zhou Y , Guan CX |
| Ref : Biomed Pharmacother , 126 :109907 , 2020 |
| Abstract : |
| PubMedSearch : Zhang_2020_Biomed.Pharmacother_126_109907 |
| PubMedID: 32114358 |
| Title : N-Benzyl-linoleamide, a Constituent of Lepidium meyenii (Maca), Is an Orally Bioavailable Soluble Epoxide Hydrolase Inhibitor That Alleviates Inflammatory Pain - Singh_2020_J.Nat.Prod_83_3689 |
| Author(s) : Singh N , Barnych B , Morisseau C , Wagner KM , Wan D , Takeshita A , Pham H , Xu T , Dandekar A , Liu JY , Hammock BD |
| Ref : Journal of Natural Products , 83 :3689 , 2020 |
| Abstract : |
| PubMedSearch : Singh_2020_J.Nat.Prod_83_3689 |
| PubMedID: 33320645 |
| Title : Suppression of inflammation and fibrosis using soluble epoxide hydrolase inhibitors enhances cardiac stem cell-based therapy - Sirish_2020_Stem.Cells.Transl.Med_9_1570 |
| Author(s) : Sirish P , Thai PN , Lee JH , Yang J , Zhang XD , Ren L , Li N , Timofeyev V , Lee KSS , Nader CE , Rowland DJ , Yechikov S , Ganaga S , Young N , Lieu DK , Yamoah EN , Hammock BD , Chiamvimonvat N |
| Ref : Stem Cells Transl Med , 9 :1570 , 2020 |
| Abstract : |
| PubMedSearch : Sirish_2020_Stem.Cells.Transl.Med_9_1570 |
| PubMedID: 32790136 |
| Title : COX-2\/sEH dual inhibitor PTUPB alleviates bleomycin-induced pulmonary fibrosis in mice via inhibiting senescence - Zhang_2020_FEBS.J_287_1666 |
| Author(s) : Zhang CY , Duan JX , Yang HH , Sun CC , Zhong WJ , Tao JH , Guan XX , Jiang HL , Hammock BD , Hwang SH , Zhou Y , Guan CX |
| Ref : Febs J , 287 :1666 , 2020 |
| Abstract : |
| PubMedSearch : Zhang_2020_FEBS.J_287_1666 |
| PubMedID: 31646730 |
| Title : 2-Oxaadamant-1-yl Ureas as Soluble Epoxide Hydrolase Inhibitors: In Vivo Evaluation in a Murine Model of Acute Pancreatitis - Codony_2020_J.Med.Chem_63_9237 |
| Author(s) : Codony S , Pujol E , Pizarro J , Feixas F , Valverde E , Loza MI , Brea JM , Saez E , Oyarzabal J , Pineda-Lucena A , Perez B , Perez C , Rodriguez-Franco MI , Leiva R , Osuna S , Morisseau C , Hammock BD , Vazquez-Carrera M , Vazquez S |
| Ref : Journal of Medicinal Chemistry , 63 :9237 , 2020 |
| Abstract : |
| PubMedSearch : Codony_2020_J.Med.Chem_63_9237 |
| PubMedID: 32787085 |
| Title : Soluble epoxide hydrolase is an endogenous regulator of obesity-induced intestinal barrier dysfunction and bacterial translocation - Wang_2020_Proc.Natl.Acad.Sci.U.S.A_117_8431 |
| Author(s) : Wang Y , Yang J , Wang W , Sanidad KZ , Cinelli MA , Wan D , Hwang SH , Kim D , Lee KSS , Xiao H , Hammock BD , Zhang G |
| Ref : Proc Natl Acad Sci U S A , 117 :8431 , 2020 |
| Abstract : |
| PubMedSearch : Wang_2020_Proc.Natl.Acad.Sci.U.S.A_117_8431 |
| PubMedID: 32220957 |
| Gene_locus related to this paper: human-EPHX2 |
| Title : Inflammation resolution: a dual-pronged approach to averting cytokine storms in COVID-19? - Panigrahy_2020_Cancer.Metastasis.Rev__ |
| Author(s) : Panigrahy D , Gilligan MM , Huang S , Gartung A , Cortes-Puch I , Sime PJ , Phipps RP , Serhan CN , Hammock BD |
| Ref : Cancer Metastasis Rev , : , 2020 |
| Abstract : |
| PubMedSearch : Panigrahy_2020_Cancer.Metastasis.Rev__ |
| PubMedID: 32385712 |
| Title : Development of Improved Double Nanobody Sandwich ELISAs for Human Soluble Epoxide Hydrolase Detection in PBMCs of Diabetic and Pre-frontal Cortex of Multiple Sclerosis Patients - Li_2020_Anal.Chem_92_7334 |
| Author(s) : Li D , Morisseau C , McReynolds CB , Duflot T , Bellien J , Nagra RM , Taha AY , Hammock BD |
| Ref : Analytical Chemistry , 92 :7334 , 2020 |
| Abstract : |
| PubMedSearch : Li_2020_Anal.Chem_92_7334 |
| PubMedID: 32253910 |
| Title : Lack of rewarding effects of a soluble epoxide hydrolase inhibitor TPPU in mice: Comparison with morphine - Wan_2020_Neuropsychopharmacol.Rep_40_412 |
| Author(s) : Wan X , Fujita Y , Chang L , Wei Y , Ma L , Wuyun G , Pu Y , Hammock BD , Hashimoto K |
| Ref : Neuropsychopharmacol Rep , 40 :412 , 2020 |
| Abstract : |
| PubMedSearch : Wan_2020_Neuropsychopharmacol.Rep_40_412 |
| PubMedID: 32896112 |
| Title : Soluble Epoxide Hydrolase Inhibition by t-TUCB Promotes Brown Adipogenesis and Reduces Serum Triglycerides in Diet-Induced Obesity - Overby_2020_Int.J.Mol.Sci_21_ |
| Author(s) : Overby H , Yang Y , Xu X , Graham K , Hildreth K , Choi S , Wan D , Morisseau C , Zeldin DC , Hammock BD , Wang S , Bettaieb A , Zhao L |
| Ref : Int J Mol Sci , 21 : , 2020 |
| Abstract : |
| PubMedSearch : Overby_2020_Int.J.Mol.Sci_21_ |
| PubMedID: 32987880 |
| Title : Eicosanoids: The Overlooked Storm in Coronavirus Disease 2019 (COVID-19)? - Hammock_2020_Am.J.Pathol_190_1782 |
| Author(s) : Hammock BD , Wang W , Gilligan MM , Panigrahy D |
| Ref : American Journal of Pathology , 190 :1782 , 2020 |
| Abstract : |
| PubMedSearch : Hammock_2020_Am.J.Pathol_190_1782 |
| PubMedID: 32650004 |
| Title : Imidazolidine-2,4,5- and pirimidine-2,4,6-triones - New primary pharmacophore for soluble epoxide hydrolase inhibitors with enhanced water solubility - Burmistrov_2020_Bioorg.Med.Chem.Lett_30_126908 |
| Author(s) : Burmistrov V , Morisseau C , D'Yachenko V , Karlov D , Butov GM , Hammock BD |
| Ref : Bioorganic & Medicinal Chemistry Lett , 30 :126908 , 2020 |
| Abstract : |
| PubMedSearch : Burmistrov_2020_Bioorg.Med.Chem.Lett_30_126908 |
| PubMedID: 31870649 |
| Title : Bioisosteric substitution of adamantane with bicyclic lipophilic groups improves water solubility of human soluble epoxide hydrolase inhibitors - Burmistrov_2020_Bioorg.Med.Chem.Lett_30_127430 |
| Author(s) : Burmistrov V , Morisseau C , Karlov D , Pitushkin D , Vernigora A , Rasskazova E , Butov GM , Hammock BD |
| Ref : Bioorganic & Medicinal Chemistry Lett , 30 :127430 , 2020 |
| Abstract : |
| PubMedSearch : Burmistrov_2020_Bioorg.Med.Chem.Lett_30_127430 |
| PubMedID: 32736212 |
| Title : Cytochrome P450-derived linoleic acid metabolites EpOMEs and DiHOMEs: A review of recent studies - Hildreth_2020_J.Nutr.Biochem__108484 |
| Author(s) : Hildreth K , Kodani SD , Hammock BD , Zhao L |
| Ref : J Nutr Biochem , :108484 , 2020 |
| Abstract : |
| PubMedSearch : Hildreth_2020_J.Nutr.Biochem__108484 |
| PubMedID: 32827665 |
| Title : Carcinogenesis: Failure of resolution of inflammation? - Fishbein_2020_Pharmacol.Ther__107670 |
| Author(s) : Fishbein A , Hammock BD , Serhan CN , Panigrahy D |
| Ref : Pharmacol Ther , :107670 , 2020 |
| Abstract : |
| PubMedSearch : Fishbein_2020_Pharmacol.Ther__107670 |
| PubMedID: 32891711 |
| Title : Development of a Highly Sensitive Enzyme-Linked Immunosorbent Assay for Mouse Soluble Epoxide Hydrolase Detection by Combining a Polyclonal Capture Antibody with a Nanobody Tracer - Li_2020_Anal.Chem_92_11654 |
| Author(s) : Li D , Cui Y , Morisseau C , Wagner KM , Cho YS , Hammock BD |
| Ref : Analytical Chemistry , 92 :11654 , 2020 |
| Abstract : |
| PubMedSearch : Li_2020_Anal.Chem_92_11654 |
| PubMedID: 32786492 |
| Title : Development of multitarget inhibitors for the treatment of pain: Design, synthesis, biological evaluation and molecular modeling studies - Wilt_2020_Bioorg.Chem_103_104165 |
| Author(s) : Wilt S , Kodani S , Le TNH , Nguyen L , Vo N , Ly T , Rodriguez M , Hudson PK , Morisseau C , Hammock BD , Pecic S |
| Ref : Bioorg Chem , 103 :104165 , 2020 |
| Abstract : |
| PubMedSearch : Wilt_2020_Bioorg.Chem_103_104165 |
| PubMedID: 32891856 |
| Title : Discovery of the First in Vivo Active Inhibitors of the Soluble Epoxide Hydrolase Phosphatase Domain - Kramer_2019_J.Med.Chem_62_8443 |
| Author(s) : Kramer JS , Woltersdorf S , Duflot T , Hiesinger K , Lillich FF , Knoll F , Wittmann SK , Klingler FM , Brunst S , Chaikuad A , Morisseau C , Hammock BD , Buccellati C , Sala A , Rovati GE , Leuillier M , Fraineau S , Rondeaux J , Hernandez-Olmos V , Heering J , Merk D , Pogoryelov D , Steinhilber D , Knapp S , Bellien J , Proschak E |
| Ref : Journal of Medicinal Chemistry , 62 :8443 , 2019 |
| Abstract : |
| PubMedSearch : Kramer_2019_J.Med.Chem_62_8443 |
| PubMedID: 31436984 |
| Title : The molecular structure of an epoxide hydrolase from Trichoderma reesei in complex with urea or amide-based inhibitors - de Oliveira_2019_Int.J.Biol.Macromol_129_653 |
| Author(s) : de Oliveira GS , Adriani PP , Ribeiro JA , Morisseau C , Hammock BD , Dias MVB , Chambergo FS |
| Ref : Int J Biol Macromol , 129 :653 , 2019 |
| Abstract : |
| PubMedSearch : de Oliveira_2019_Int.J.Biol.Macromol_129_653 |
| PubMedID: 30771398 |
| Gene_locus related to this paper: hypjq-g0r7e2 |
| Title : Substrate and inhibitor selectivity, and biological activity of an epoxide hydrolase from Trichoderma reesei - de Oliveira_2019_Mol.Biol.Rep_46_371 |
| Author(s) : de Oliveira GS , Adriani PP , Wu H , Morisseau C , Hammock BD , Chambergo FS |
| Ref : Mol Biol Rep , 46 :371 , 2019 |
| Abstract : |
| PubMedSearch : de Oliveira_2019_Mol.Biol.Rep_46_371 |
| PubMedID: 30426381 |
| Gene_locus related to this paper: hypjq-g0r7e2 |
| Title : Inhibition of soluble epoxide hydrolase attenuates a high-fat diet-mediated renal injury by activating PAX2 and AMPK - Luo_2019_Proc.Natl.Acad.Sci.U.S.A_116_5154 |
| Author(s) : Luo Y , Wu MY , Deng BQ , Huang J , Hwang SH , Li MY , Zhou CY , Zhang QY , Yu HB , Zhao DK , Zhang G , Qin L , Peng A , Hammock BD , Liu JY |
| Ref : Proc Natl Acad Sci U S A , 116 :5154 , 2019 |
| Abstract : |
| PubMedSearch : Luo_2019_Proc.Natl.Acad.Sci.U.S.A_116_5154 |
| PubMedID: 30804206 |
| Title : In vitro and in vivo Metabolism of a Potent Inhibitor of Soluble Epoxide Hydrolase, 1-(1-Propionylpiperidin-4-yl)-3-(4-(trifluoromethoxy)phenyl)urea - Wan_2019_Front.Pharmacol_10_464 |
| Author(s) : Wan D , Yang J , McReynolds CB , Barnych B , Wagner KM , Morisseau C , Hwang SH , Sun J , Blocher R , Hammock BD |
| Ref : Front Pharmacol , 10 :464 , 2019 |
| Abstract : |
| PubMedSearch : Wan_2019_Front.Pharmacol_10_464 |
| PubMedID: 31143115 |
| Title : Development of multitarget agents possessing soluble epoxide hydrolase inhibitory activity - Hiesinger_2019_Prostaglandins.Other.Lipid.Mediat_140_31 |
| Author(s) : Hiesinger K , Wagner KM , Hammock BD , Proschak E , Hwang SH |
| Ref : Prostaglandins Other Lipid Mediat , 140 :31 , 2019 |
| Abstract : |
| PubMedSearch : Hiesinger_2019_Prostaglandins.Other.Lipid.Mediat_140_31 |
| PubMedID: 30593866 |
| Title : N-Substituted amino acid inhibitors of the phosphatase domain of the soluble epoxide hydrolase - Matsumoto_2019_Biochem.Biophys.Res.Commun_515_248 |
| Author(s) : Matsumoto N , Kataoka M , Hirosaki H , Morisseau C , Hammock BD , Suzuki E , Hasumi K |
| Ref : Biochemical & Biophysical Research Communications , 515 :248 , 2019 |
| Abstract : |
| PubMedSearch : Matsumoto_2019_Biochem.Biophys.Res.Commun_515_248 |
| PubMedID: 31146915 |
| Title : Anti-inflammatory treatment with a soluble epoxide hydrolase inhibitor attenuates seizures and epilepsy-associated depression in the LiCl-pilocarpine post-status epilepticus rat model - Shen_2019_Brain.Behav.Immun_81_535 |
| Author(s) : Shen Y , Peng W , Chen Q , Hammock BD , Liu J , Li D , Yang J , Ding J , Wang X |
| Ref : Brain Behavior & Immunity , 81 :535 , 2019 |
| Abstract : |
| PubMedSearch : Shen_2019_Brain.Behav.Immun_81_535 |
| PubMedID: 31306773 |
| Title : Suppression of chemotherapy-induced cytokine\/lipid mediator surge and ovarian cancer by a dual COX-2\/sEH inhibitor - Gartung_2019_Proc.Natl.Acad.Sci.U.S.A_116_1698 |
| Author(s) : Gartung A , Yang J , Sukhatme VP , Bielenberg DR , Fernandes D , Chang J , Schmidt BA , Hwang SH , Zurakowski D , Huang S , Kieran MW , Hammock BD , Panigrahy D |
| Ref : Proc Natl Acad Sci U S A , 116 :1698 , 2019 |
| Abstract : |
| PubMedSearch : Gartung_2019_Proc.Natl.Acad.Sci.U.S.A_116_1698 |
| PubMedID: 30647111 |
| Title : Exploring the size of the lipophilic unit of the soluble epoxide hydrolase inhibitors - Codony_2019_Bioorg.Med.Chem_27_115078 |
| Author(s) : Codony S , Valverde E , Leiva R , Brea J , Isabel Loza M , Morisseau C , Hammock BD , Vazquez S |
| Ref : Bioorganic & Medicinal Chemistry , 27 :115078 , 2019 |
| Abstract : |
| PubMedSearch : Codony_2019_Bioorg.Med.Chem_27_115078 |
| PubMedID: 31488357 |
| Title : Phytochemical constituents from Scutellaria baicalensis in soluble epoxide hydrolase inhibition: Kinetics and interaction mechanism merged with simulations - Liu_2019_Int.J.Biol.Macromol_133_1187 |
| Author(s) : Liu ZB , Sun CP , Xu JX , Morisseau C , Hammock BD , Qiu F |
| Ref : Int J Biol Macromol , 133 :1187 , 2019 |
| Abstract : |
| PubMedSearch : Liu_2019_Int.J.Biol.Macromol_133_1187 |
| PubMedID: 30980876 |
| Title : Key role of soluble epoxide hydrolase in the neurodevelopmental disorders of offspring after maternal immune activation - Ma_2019_Proc.Natl.Acad.Sci.U.S.A_116_7083 |
| Author(s) : Ma M , Ren Q , Yang J , Zhang K , Xiong Z , Ishima T , Pu Y , Hwang SH , Toyoshima M , Iwayama Y , Hisano Y , Yoshikawa T , Hammock BD , Hashimoto K |
| Ref : Proc Natl Acad Sci U S A , 116 :7083 , 2019 |
| Abstract : |
| PubMedSearch : Ma_2019_Proc.Natl.Acad.Sci.U.S.A_116_7083 |
| PubMedID: 30890645 |
| Title : Inhibition of soluble epoxide hydrolase ameliorates hyperhomocysteinemia-induced hepatic steatosis by enhancing beta-oxidation of fatty acid in mice - Yao_2019_Am.J.Physiol.Gastrointest.Liver.Physiol_316_G527 |
| Author(s) : Yao L , Cao B , Cheng Q , Cai W , Ye C , Liang J , Liu W , Tan L , Yan M , Li B , He J , Hwang SH , Zhang X , Wang C , Ai D , Hammock BD , Zhu Y |
| Ref : American Journal of Physiology Gastrointest Liver Physiol , 316 :G527 , 2019 |
| Abstract : |
| PubMedSearch : Yao_2019_Am.J.Physiol.Gastrointest.Liver.Physiol_316_G527 |
| PubMedID: 30789748 |
| Title : 1-Trifluoromethoxyphenyl-3-(1-propionylpiperidin-4-yl) Urea, a Selective and Potent Dual Inhibitor of Soluble Epoxide Hydrolase and p38 Kinase Intervenes in Alzheimer's Signaling in Human Nerve Cells - Liang_2019_ACS.Chem.Neurosci_10_4018 |
| Author(s) : Liang Z , Zhang B , Xu M , Morisseau C , Hwang SH , Hammock BD , Li QX |
| Ref : ACS Chem Neurosci , 10 :4018 , 2019 |
| Abstract : |
| PubMedSearch : Liang_2019_ACS.Chem.Neurosci_10_4018 |
| PubMedID: 31378059 |
| Title : Effect Of Dual sEH\/COX-2 Inhibition on Allergen-Induced Airway Inflammation - Dileepan_2019_Front.Pharmacol_10_1118 |
| Author(s) : Dileepan M , Rastle-Simpson S , Greenberg Y , Wijesinghe DS , Kumar NG , Yang J , Hwang SH , Hammock BD , Sriramarao P , Rao SP |
| Ref : Front Pharmacol , 10 :1118 , 2019 |
| Abstract : |
| PubMedSearch : Dileepan_2019_Front.Pharmacol_10_1118 |
| PubMedID: 31611798 |
| Title : Pharmacological Blockade of Soluble Epoxide Hydrolase Attenuates the Progression of Congestive Heart Failure Combined With Chronic Kidney Disease: Insights From Studies With Fawn-Hooded Hypertensive Rats - Vackova_2019_Front.Pharmacol_10_18 |
| Author(s) : Vackova S , Kopkan L , Kikerlova S , Huskova Z , Sadowski J , Kompanowska-Jezierska E , Hammock BD , Imig JD , Taborsky M , Melenovsky V , Cervenka L |
| Ref : Front Pharmacol , 10 :18 , 2019 |
| Abstract : |
| PubMedSearch : Vackova_2019_Front.Pharmacol_10_18 |
| PubMedID: 30728778 |
| Title : Docosahexaenoic Acid Increases the Potency of Soluble Epoxide Hydrolase Inhibitor in Alleviating Streptozotocin-Induced Alzheimer's Disease-Like Complications of Diabetes - Pardeshi_2019_Front.Pharmacol_10_288 |
| Author(s) : Pardeshi R , Bolshette N , Gadhave K , Arfeen M , Ahmed S , Jamwal R , Hammock BD , Lahkar M , Goswami SK |
| Ref : Front Pharmacol , 10 :288 , 2019 |
| Abstract : |
| PubMedSearch : Pardeshi_2019_Front.Pharmacol_10_288 |
| PubMedID: 31068802 |
| Title : Brain oxylipin concentrations following hypercapnia\/ischemia: effects of brain dissection and dissection time - Hennebelle_2019_J.Lipid.Res_60_671 |
| Author(s) : Hennebelle M , Metherel AH , Kitson AP , Otoki Y , Yang J , Lee KSS , Hammock BD , Bazinet RP , Taha AY |
| Ref : J Lipid Res , 60 :671 , 2019 |
| Abstract : |
| PubMedSearch : Hennebelle_2019_J.Lipid.Res_60_671 |
| PubMedID: 30463986 |
| Title : Humble beginnings with big goals: Small molecule soluble epoxide hydrolase inhibitors for treating CNS disorders - Zarriello_2019_Prog.Neurobiol_172_23 |
| Author(s) : Zarriello S , Tuazon JP , Corey S , Schimmel S , Rajani M , Gorsky A , Incontri D , Hammock BD , Borlongan CV |
| Ref : Prog Neurobiol , 172 :23 , 2019 |
| Abstract : |
| PubMedSearch : Zarriello_2019_Prog.Neurobiol_172_23 |
| PubMedID: 30447256 |
| Title : Pharmaceutical Effects of Inhibiting the Soluble Epoxide Hydrolase in Canine Osteoarthritis - McReynolds_2019_Front.Pharmacol_10_533 |
| Author(s) : McReynolds CB , Hwang SH , Yang J , Wan D , Wagner K , Morisseau C , Li D , Schmidt WK , Hammock BD |
| Ref : Front Pharmacol , 10 :533 , 2019 |
| Abstract : |
| PubMedSearch : McReynolds_2019_Front.Pharmacol_10_533 |
| PubMedID: 31214021 |
| Title : Computer-Aided Selective Optimization of Side Activities of Talinolol - Hiesinger_2019_ACS.Med.Chem.Lett_10_899 |
| Author(s) : Hiesinger K , Kramer JS , Achenbach J , Moser D , Weber J , Wittmann SK , Morisseau C , Angioni C , Geisslinger G , Kahnt AS , Kaiser A , Proschak A , Steinhilber D , Pogoryelov D , Wagner K , Hammock BD , Proschak E |
| Ref : ACS Med Chem Lett , 10 :899 , 2019 |
| Abstract : |
| PubMedSearch : Hiesinger_2019_ACS.Med.Chem.Lett_10_899 |
| PubMedID: 31223445 |
| Gene_locus related to this paper: human-EPHX2 |
| Title : Prophylactic inhibition of soluble epoxide hydrolase delays onset of nephritis and ameliorates kidney damage in NZB\/W F1 mice - Klocke_2019_Sci.Rep_9_8993 |
| Author(s) : Klocke J , Ulu A , Wu K , Rudolph B , Dragun D , Gollasch M , Schunck WH , Hammock BD , Riemekasten G , Enghard P |
| Ref : Sci Rep , 9 :8993 , 2019 |
| Abstract : |
| PubMedSearch : Klocke_2019_Sci.Rep_9_8993 |
| PubMedID: 31222024 |
| Title : Effect of angiotensin-converting enzyme blockade, alone or combined with blockade of soluble epoxide hydrolase, on the course of congestive heart failure and occurrence of renal dysfunction in Ren-2 transgenic hypertensive rats with aorto-caval fistula - Kala_2018_Physiol.Res_67_401 |
| Author(s) : Kala P , Sedlakova L , Skaroupkova P , Kopkan L , Vanourkova Z , Taborsky M , Nishiyama A , Hwang SH , Hammock BD , Sadowski J , Melenovsky V , Imig JD , Cervenka L |
| Ref : Physiol Res , 67 :401 , 2018 |
| Abstract : |
| PubMedSearch : Kala_2018_Physiol.Res_67_401 |
| PubMedID: 29527914 |
| Title : Novel piperidine-derived amide sEH inhibitors as mediators of lipid metabolism with improved stability - Pecic_2018_Prostaglandins.Other.Lipid.Mediat_136_90 |
| Author(s) : Pecic S , Zeki AA , Xu X , Jin GY , Zhang S , Kodani S , Halim M , Morisseau C , Hammock BD , Deng SX |
| Ref : Prostaglandins Other Lipid Mediat , 136 :90 , 2018 |
| Abstract : |
| PubMedSearch : Pecic_2018_Prostaglandins.Other.Lipid.Mediat_136_90 |
| PubMedID: 29567338 |
| Title : Soluble epoxide hydrolase inhibitor, APAU, protects dopaminergic neurons against rotenone induced neurotoxicity: Implications for Parkinson's disease - Lakkappa_2018_Neurotoxicol_70_135 |
| Author(s) : Lakkappa N , Krishnamurthy PT , M DP , Hammock BD , Hwang SH |
| Ref : Neurotoxicology , 70 :135 , 2018 |
| Abstract : |
| PubMedSearch : Lakkappa_2018_Neurotoxicol_70_135 |
| PubMedID: 30472438 |
| Title : Evaluation of antiparkinson activity of PTUPB by measuring dopamine and its metabolites in Drosophila melanogaster: LC-MS\/MS method development - Lakkappa_2018_J.Pharm.Biomed.Anal_149_457 |
| Author(s) : Lakkappa N , Krishnamurthy PT , Yamjala K , Hwang SH , Hammock BD , Babu B |
| Ref : J Pharm Biomed Anal , 149 :457 , 2018 |
| Abstract : |
| PubMedSearch : Lakkappa_2018_J.Pharm.Biomed.Anal_149_457 |
| PubMedID: 29169114 |
| Title : An inhibitor of soluble epoxide hydrolase ameliorates diabetes-induced learning and memory impairment in rats - Minaz_2018_Prostaglandins.Other.Lipid.Mediat_136_84 |
| Author(s) : Minaz N , Razdan R , Hammock BD , Goswami SK |
| Ref : Prostaglandins Other Lipid Mediat , 136 :84 , 2018 |
| Abstract : |
| PubMedSearch : Minaz_2018_Prostaglandins.Other.Lipid.Mediat_136_84 |
| PubMedID: 29751149 |
| Title : Orally Available Soluble Epoxide Hydrolase\/Phosphodiesterase 4 Dual Inhibitor Treats Inflammatory Pain - Blocher_2018_J.Med.Chem_61_3541 |
| Author(s) : Blocher R , Wagner KM , Gopireddy RR , Harris TR , Wu H , Barnych B , Hwang SH , Xiang YK , Proschak E , Morisseau C , Hammock BD |
| Ref : Journal of Medicinal Chemistry , 61 :3541 , 2018 |
| Abstract : |
| PubMedSearch : Blocher_2018_J.Med.Chem_61_3541 |
| PubMedID: 29614224 |
| Title : COX-2\/sEH Dual Inhibitor PTUPB Potentiates the Antitumor Efficacy of Cisplatin - Wang_2018_Mol.Cancer.Ther_17_474 |
| Author(s) : Wang F , Zhang H , Ma AH , Yu W , Zimmermann M , Yang J , Hwang SH , Zhu D , Lin TY , Malfatti M , Turteltaub KW , Henderson PT , Airhart S , Hammock BD , Yuan J , de Vere White RW , Pan CX |
| Ref : Mol Cancer Ther , 17 :474 , 2018 |
| Abstract : |
| PubMedSearch : Wang_2018_Mol.Cancer.Ther_17_474 |
| PubMedID: 29284644 |
| Title : Combined Inhibition of Soluble Epoxide Hydrolase and Renin-Angiotensin System Exhibits Superior Renoprotection to Renin-Angiotensin System Blockade in 5\/6 Nephrectomized Ren-2 Transgenic Hypertensive Rats with Established Chronic Kidney Disease - Certikova_2018_Kidney.Blood.Press.Res_43_329 |
| Author(s) : Certikova Chabova V , Kujal P , Skaroupkova P , Varnourkova Z , Vackova S , Huskova Z , Kikerlova S , Sadowski J , Kompanowska-Jezierska E , Baranowska I , Hwang SH , Hammock BD , Imig JD , Tesar V , Cervenka L |
| Ref : Kidney Blood Press Res , 43 :329 , 2018 |
| Abstract : |
| PubMedSearch : Certikova_2018_Kidney.Blood.Press.Res_43_329 |
| PubMedID: 29529602 |
| Title : Inhibition of soluble epoxide hydrolase attenuates eosinophil recruitment and food allergen-induced gastrointestinal inflammation - Bastan_2018_J.Leukoc.Biol_104_109 |
| Author(s) : Bastan I , Ge XN , Dileepan M , Greenberg YG , Guedes AG , Hwang SH , Hammock BD , Washabau RJ , Rao SP , Sriramarao P |
| Ref : J Leukoc Biol , 104 :109 , 2018 |
| Abstract : |
| PubMedSearch : Bastan_2018_J.Leukoc.Biol_104_109 |
| PubMedID: 29345370 |
| Title : Adamantyl thioureas as soluble epoxide hydrolase inhibitors - Burmistrov_2018_Bioorg.Med.Chem.Lett_28_2302 |
| Author(s) : Burmistrov V , Morisseau C , Pitushkin D , Karlov D , Fayzullin RR , Butov GM , Hammock BD |
| Ref : Bioorganic & Medicinal Chemistry Lett , 28 :2302 , 2018 |
| Abstract : |
| PubMedSearch : Burmistrov_2018_Bioorg.Med.Chem.Lett_28_2302 |
| PubMedID: 29803731 |
| Title : Identification and optimization of soluble epoxide hydrolase inhibitors with dual potency towards fatty acid amide hydrolase - Kodani_2018_Bioorg.Med.Chem.Lett_28_762 |
| Author(s) : Kodani SD , Bhakta S , Hwang SH , Pakhomova S , Newcomer ME , Morisseau C , Hammock BD |
| Ref : Bioorganic & Medicinal Chemistry Lett , 28 :762 , 2018 |
| Abstract : |
| PubMedSearch : Kodani_2018_Bioorg.Med.Chem.Lett_28_762 |
| PubMedID: 29366648 |
| Gene_locus related to this paper: human-EPHX2 |
| Title : Soluble epoxide hydrolase inhibition decreases reperfusion injury after focal cerebral ischemia - Tu_2018_Sci.Rep_8_5279 |
| Author(s) : Tu R , Armstrong J , Lee KSS , Hammock BD , Sapirstein A , Koehler RC |
| Ref : Sci Rep , 8 :5279 , 2018 |
| Abstract : |
| PubMedSearch : Tu_2018_Sci.Rep_8_5279 |
| PubMedID: 29588470 |
| Title : Metabolic\/inflammatory\/vascular comorbidity in psychiatric disorders\; soluble epoxide hydrolase (sEH) as a possible new target - Swardfager_2018_Neurosci.Biobehav.Rev_87_56 |
| Author(s) : Swardfager W , Hennebelle M , Yu D , Hammock BD , Levitt AJ , Hashimoto K , Taha AY |
| Ref : Neurosci Biobehav Rev , 87 :56 , 2018 |
| Abstract : |
| PubMedSearch : Swardfager_2018_Neurosci.Biobehav.Rev_87_56 |
| PubMedID: 29407524 |
| Title : Estrogen-dependent epigenetic regulation of soluble epoxide hydrolase via DNA methylation - Yang_2018_Proc.Natl.Acad.Sci.U.S.A_115_613 |
| Author(s) : Yang YM , Sun D , Kandhi S , Froogh G , Zhuge J , Huang W , Hammock BD , Huang A |
| Ref : Proc Natl Acad Sci U S A , 115 :613 , 2018 |
| Abstract : |
| PubMedSearch : Yang_2018_Proc.Natl.Acad.Sci.U.S.A_115_613 |
| PubMedID: 29295935 |
| Title : Pharmacokinetics and antinociceptive effects of the soluble epoxide hydrolase inhibitor t-TUCB in horses with experimentally induced radiocarpal synovitis - Guedes_2018_J.Vet.Pharmacol.Ther_41_230 |
| Author(s) : Guedes AGP , Aristizabal F , Sole A , Adedeji A , Brosnan R , Knych H , Yang J , Hwang SH , Morisseau C , Hammock BD |
| Ref : J Vet Pharmacol Ther , 41 :230 , 2018 |
| Abstract : |
| PubMedSearch : Guedes_2018_J.Vet.Pharmacol.Ther_41_230 |
| PubMedID: 29067696 |
| Title : Catalytic activities of mammalian epoxide hydrolases with cis and trans fatty acid epoxides relevant to skin barrier function - Yamanashi_2018_J.Lipid.Res_59_684 |
| Author(s) : Yamanashi H , Boeglin WE , Morisseau C , Davis RW , Sulikowski GA , Hammock BD , Brash AR |
| Ref : J Lipid Res , 59 :684 , 2018 |
| Abstract : |
| PubMedSearch : Yamanashi_2018_J.Lipid.Res_59_684 |
| PubMedID: 29459481 |
| Title : Design and Potency of Dual Soluble Epoxide Hydrolase\/Fatty Acid Amide Hydrolase Inhibitors - Kodani_2018_ACS.Omega_3_14076 |
| Author(s) : Kodani SD , Wan D , Wagner KM , Hwang SH , Morisseau C , Hammock BD |
| Ref : ACS Omega , 3 :14076 , 2018 |
| Abstract : |
| PubMedSearch : Kodani_2018_ACS.Omega_3_14076 |
| PubMedID: 30411058 |
| Title : Reduced carboxylesterase 1 is associated with endothelial injury in methamphetamine-induced pulmonary arterial hypertension - Orcholski_2017_Am.J.Physiol.Lung.Cell.Mol.Physiol_313_L252 |
| Author(s) : Orcholski ME , Khurshudyan A , Shamskhou EA , Yuan K , Chen IY , Kodani SD , Morisseau C , Hammock BD , Hong EM , Alexandrova L , Alastalo TP , Berry G , Zamanian RT , de Jesus Perez VA |
| Ref : American Journal of Physiology Lung Cell Mol Physiol , 313 :L252 , 2017 |
| Abstract : |
| PubMedSearch : Orcholski_2017_Am.J.Physiol.Lung.Cell.Mol.Physiol_313_L252 |
| PubMedID: 28473326 |
| Gene_locus related to this paper: human-CES1 |
| Title : Modulation of mitochondrial dysfunction and endoplasmic reticulum stress are key mechanisms for the wide-ranging actions of epoxy fatty acids and soluble epoxide hydrolase inhibitors - Inceoglu_2017_Prostaglandins.Other.Lipid.Mediat_133_68 |
| Author(s) : Inceoglu B , Bettaieb A , Haj FG , Gomes AV , Hammock BD |
| Ref : Prostaglandins Other Lipid Mediat , 133 :68 , 2017 |
| Abstract : |
| PubMedSearch : Inceoglu_2017_Prostaglandins.Other.Lipid.Mediat_133_68 |
| PubMedID: 28847566 |
| Title : Occurrence of urea-based soluble epoxide hydrolase inhibitors from the plants in the order Brassicales - Kitamura_2017_PLoS.One_12_e0176571 |
| Author(s) : Kitamura S , Morisseau C , Harris TR , Inceoglu B , Hammock BD |
| Ref : PLoS ONE , 12 :e0176571 , 2017 |
| Abstract : |
| PubMedSearch : Kitamura_2017_PLoS.One_12_e0176571 |
| PubMedID: 28472063 |
| Title : Pseudomonas aeruginosa sabotages the generation of host proresolving lipid mediators - Flitter_2017_Proc.Natl.Acad.Sci.U.S.A_114_136 |
| Author(s) : Flitter BA , Hvorecny KL , Ono E , Eddens T , Yang J , Kwak DH , Bahl CD , Hampton TH , Morisseau C , Hammock BD , Liu X , Lee JS , Kolls JK , Levy BD , Madden DR , Bomberger JM |
| Ref : Proc Natl Acad Sci U S A , 114 :136 , 2017 |
| Abstract : |
| PubMedSearch : Flitter_2017_Proc.Natl.Acad.Sci.U.S.A_114_136 |
| PubMedID: 27980032 |
| Gene_locus related to this paper: pseae-PA2934 |
| Title : Probing the orientation of inhibitor and epoxy-eicosatrienoic acid binding in the active site of soluble epoxide hydrolase - Lee_2017_Arch.Biochem.Biophys_613_1 |
| Author(s) : Lee KS , Henriksen NM , Ng CJ , Yang J , Jia W , Morisseau C , Andaya A , Gilson MK , Hammock BD |
| Ref : Archives of Biochemistry & Biophysics , 613 :1 , 2017 |
| Abstract : |
| PubMedSearch : Lee_2017_Arch.Biochem.Biophys_613_1 |
| PubMedID: 27983948 |
| Title : Soluble Epoxide Hydrolase Inhibitor Attenuates Lipopolysaccharide-Induced Acute Lung Injury and Improves Survival in Mice - Zhou_2017_Shock_47_638 |
| Author(s) : Zhou Y , Liu T , Duan JX , Li P , Sun GY , Liu YP , Zhang J , Dong L , Lee KSS , Hammock BD , Jiang JX , Guan CX |
| Ref : Shock , 47 :638 , 2017 |
| Abstract : |
| PubMedSearch : Zhou_2017_Shock_47_638 |
| PubMedID: 27753791 |
| Title : Soluble Epoxide Hydrolase Pharmacological Inhibition Decreases Alveolar Bone Loss by Modulating Host Inflammatory Response, RANK-Related Signaling, Endoplasmic Reticulum Stress, and Apoptosis - Trindade-da-Silva_2017_J.Pharmacol.Exp.Ther_361_408 |
| Author(s) : Trindade-da-Silva CA , Bettaieb A , Napimoga MH , Lee KSS , Inceoglu B , Ueira-Vieira C , Bruun D , Goswami SK , Haj FG , Hammock BD |
| Ref : Journal of Pharmacology & Experimental Therapeutics , 361 :408 , 2017 |
| Abstract : |
| PubMedSearch : Trindade-da-Silva_2017_J.Pharmacol.Exp.Ther_361_408 |
| PubMedID: 28356494 |
| Title : Altered soluble epoxide hydrolase-derived oxylipins in patients with seasonal major depression: An exploratory study - Hennebelle_2017_Psychiatry.Res_252_94 |
| Author(s) : Hennebelle M , Otoki Y , Yang J , Hammock BD , Levitt AJ , Taha AY , Swardfager W |
| Ref : Psychiatry Res , 252 :94 , 2017 |
| Abstract : |
| PubMedSearch : Hennebelle_2017_Psychiatry.Res_252_94 |
| PubMedID: 28259037 |
| Title : Soluble epoxide hydrolase in podocytes is a significant contributor to renal function under hyperglycemia - Bettaieb_2017_Biochim.Biophys.Acta_1861_2758 |
| Author(s) : Bettaieb A , Koike S , Hsu MF , Ito Y , Chahed S , Bachaalany S , Gruzdev A , Calvo-Rubio M , Lee KSS , Inceoglu B , Imig JD , Villalba JM , Zeldin DC , Hammock BD , Haj FG |
| Ref : Biochimica & Biophysica Acta , 1861 :2758 , 2017 |
| Abstract : |
| PubMedSearch : Bettaieb_2017_Biochim.Biophys.Acta_1861_2758 |
| PubMedID: 28757338 |
| Title : Endothelial Nox4-based NADPH oxidase regulates atherosclerosis via soluble epoxide hydrolase - Hu_2017_Biochim.Biophys.Acta_1863_1382 |
| Author(s) : Hu P , Wu X , Khandelwal AR , Yu W , Xu Z , Chen L , Yang J , Weisbrod RM , Lee KSS , Seta F , Hammock BD , Cohen RA , Zeng C , Tong X |
| Ref : Biochimica & Biophysica Acta , 1863 :1382 , 2017 |
| Abstract : |
| PubMedSearch : Hu_2017_Biochim.Biophys.Acta_1863_1382 |
| PubMedID: 28185955 |
| Title : Soluble epoxide hydrolase inhibition alleviates neuropathy in Akita (Ins2 Akita) mice - Wagner_2017_Behav.Brain.Res_326_69 |
| Author(s) : Wagner K , Gilda J , Yang J , Wan D , Morisseau C , Gomes AV , Hammock BD |
| Ref : Behavioural Brain Research , 326 :69 , 2017 |
| Abstract : |
| PubMedSearch : Wagner_2017_Behav.Brain.Res_326_69 |
| PubMedID: 28259677 |
| Title : Inhibition of soluble epoxide hydrolase augments astrocyte release of vascular endothelial growth factor and neuronal recovery after oxygen-glucose deprivation - Zhang_2017_J.Neurochem_140_814 |
| Author(s) : Zhang Y , Hong G , Lee KS , Hammock BD , Gebremedhin D , Harder DR , Koehler RC , Sapirstein A |
| Ref : Journal of Neurochemistry , 140 :814 , 2017 |
| Abstract : |
| PubMedSearch : Zhang_2017_J.Neurochem_140_814 |
| PubMedID: 28002622 |
| Title : Soluble epoxide hydrolase activity and pharmacologic inhibition in horses with chronic severe laminitis - Guedes_2017_Equine.Vet.J_49_345 |
| Author(s) : Guedes A , Galuppo L , Hood D , Hwang SH , Morisseau C , Hammock BD |
| Ref : Equine Vet J , 49 :345 , 2017 |
| Abstract : |
| PubMedSearch : Guedes_2017_Equine.Vet.J_49_345 |
| PubMedID: 27338788 |
| Title : Inhibitors of soluble epoxide hydrolase minimize ischemia-reperfusion-induced cardiac damage in normal, hypertensive, and diabetic rats - Islam_2017_Cardiovasc.Ther_35_ |
| Author(s) : Islam O , Patil P , Goswami SK , Razdan R , Inamdar MN , Rizwan M , Mathew J , Inceoglu B , Stephen Lee KS , Hwang SH , Hammock BD |
| Ref : Cardiovasc Ther , 35 : , 2017 |
| Abstract : |
| PubMedSearch : Islam_2017_Cardiovasc.Ther_35_ |
| PubMedID: 28296232 |
| Title : Soluble epoxide hydrolase as a therapeutic target for pain, inflammatory and neurodegenerative diseases - Wagner_2017_Pharmacol.Ther_180_62 |
| Author(s) : Wagner KM , McReynolds CB , Schmidt WK , Hammock BD |
| Ref : Pharmacol Ther , 180 :62 , 2017 |
| Abstract : |
| PubMedSearch : Wagner_2017_Pharmacol.Ther_180_62 |
| PubMedID: 28642117 |
| Title : Effects of adamantane alterations on soluble epoxide hydrolase inhibition potency, physical properties and metabolic stability - Burmistrov_2017_Bioorg.Chem_76_510 |
| Author(s) : Burmistrov V , Morisseau C , Harris TR , Butov G , Hammock BD |
| Ref : Bioorg Chem , 76 :510 , 2017 |
| Abstract : |
| PubMedSearch : Burmistrov_2017_Bioorg.Chem_76_510 |
| PubMedID: 29310082 |
| Title : Exploring adduct formation between human serum albumin and eleven organophosphate ester flame retardants and plasticizers using MALDI-TOF\/TOF and LC-Q\/TOF - Chu_2017_Chemosphere_180_169 |
| Author(s) : Chu S , Baker MR , Leong G , Letcher RJ , Gee SJ , Hammock BD , Li QX |
| Ref : Chemosphere , 180 :169 , 2017 |
| Abstract : |
| PubMedSearch : Chu_2017_Chemosphere_180_169 |
| PubMedID: 28407546 |
| Title : Inhibition of soluble epoxide hydrolase prevents diabetic retinopathy - Hu_2017_Nature_552_248 |
| Author(s) : Hu J , Dziumbla S , Lin J , Bibli SI , Zukunft S , de Mos J , Awwad K , Fromel T , Jungmann A , Devraj K , Cheng Z , Wang L , Fauser S , Eberhart CG , Sodhi A , Hammock BD , Liebner S , Muller OJ , Glaubitz C , Hammes HP , Popp R , Fleming I |
| Ref : Nature , 552 :248 , 2017 |
| Abstract : |
| PubMedSearch : Hu_2017_Nature_552_248 |
| PubMedID: 29211719 |
| Title : Active-Site Flexibility and Substrate Specificity in a Bacterial Virulence Factor: Crystallographic Snapshots of an Epoxide Hydrolase - Hvorecny_2017_Structure_25_697 |
| Author(s) : Hvorecny KL , Bahl CD , Kitamura S , Lee KSS , Hammock BD , Morisseau C , Madden DR |
| Ref : Structure , 25 :697 , 2017 |
| Abstract : |
| PubMedSearch : Hvorecny_2017_Structure_25_697 |
| PubMedID: 28392259 |
| Gene_locus related to this paper: pseae-PA2934 |
| Title : In Vitro Metabolism of Oprozomib, an Oral Proteasome Inhibitor: Role of Epoxide Hydrolases and Cytochrome P450s - Wang_2017_Drug.Metab.Dispos_45_712 |
| Author(s) : Wang Z , Fang Y , Teague J , Wong H , Morisseau C , Hammock BD , Rock DA |
| Ref : Drug Metabolism & Disposition: The Biological Fate of Chemicals , 45 :712 , 2017 |
| Abstract : |
| PubMedSearch : Wang_2017_Drug.Metab.Dispos_45_712 |
| PubMedID: 28428366 |
| Title : Soluble epoxide hydrolase inhibitor 1-trifluoromethoxyphenyl-3- (1-propionylpiperidin-4-yl) urea attenuates bleomycin-induced pulmonary fibrosis in mice - Zhou_2016_Cell.Tissue.Res_363_399 |
| Author(s) : Zhou Y , Sun GY , Liu T , Duan JX , Zhou HF , Lee KS , Hammock BD , Fang X , Jiang JX , Guan CX |
| Ref : Cell Tissue Research , 363 :399 , 2016 |
| Abstract : |
| PubMedSearch : Zhou_2016_Cell.Tissue.Res_363_399 |
| PubMedID: 26310139 |
| Title : Gene deficiency and pharmacological inhibition of soluble epoxide hydrolase confers resilience to repeated social defeat stress - Ren_2016_Proc.Natl.Acad.Sci.U.S.A_113_E1944 |
| Author(s) : Ren Q , Ma M , Ishima T , Morisseau C , Yang J , Wagner KM , Zhang JC , Yang C , Yao W , Dong C , Han M , Hammock BD , Hashimoto K |
| Ref : Proc Natl Acad Sci U S A , 113 :E1944 , 2016 |
| Abstract : |
| PubMedSearch : Ren_2016_Proc.Natl.Acad.Sci.U.S.A_113_E1944 |
| PubMedID: 26976569 |
| Gene_locus related to this paper: mouse-hyes |
| Title : Anti-Ulcer Efficacy of Soluble Epoxide Hydrolase Inhibitor TPPU on Diclofenac-Induced Intestinal Ulcers - Goswami_2016_J.Pharmacol.Exp.Ther_357_529 |
| Author(s) : Goswami SK , Wan D , Yang J , Trindade da Silva CA , Morisseau C , Kodani SD , Yang GY , Inceoglu B , Hammock BD |
| Ref : Journal of Pharmacology & Experimental Therapeutics , 357 :529 , 2016 |
| Abstract : |
| PubMedSearch : Goswami_2016_J.Pharmacol.Exp.Ther_357_529 |
| PubMedID: 26989141 |
| Title : Ingestion of the epoxide hydrolase inhibitor AUDA modulates immune responses of the mosquito, Culex quinquefasciatus during blood feeding - Xu_2016_Insect.Biochem.Mol.Biol_76_62 |
| Author(s) : Xu J , Morisseau C , Yang J , Lee KS , Kamita SG , Hammock BD |
| Ref : Insect Biochemistry & Molecular Biology , 76 :62 , 2016 |
| Abstract : |
| PubMedSearch : Xu_2016_Insect.Biochem.Mol.Biol_76_62 |
| PubMedID: 27369469 |
| Title : Inhibition of soluble epoxide hydrolase alleviated atherosclerosis by reducing monocyte infiltration in Ldlr(-\/-) mice - Li_2016_J.Mol.Cell.Cardiol_98_128 |
| Author(s) : Li D , Liu Y , Zhang X , Lv H , Pang W , Sun X , Gan LM , Hammock BD , Ai D , Zhu Y |
| Ref : Journal of Molecular & Cellular Cardiology , 98 :128 , 2016 |
| Abstract : |
| PubMedSearch : Li_2016_J.Mol.Cell.Cardiol_98_128 |
| PubMedID: 27496380 |
| Title : Parabens inhibit fatty acid amide hydrolase: A potential role in paraben-enhanced 3T3-L1 adipocyte differentiation - Kodani_2016_Toxicol.Lett_262_92 |
| Author(s) : Kodani SD , Overby HB , Morisseau C , Chen J , Zhao L , Hammock BD |
| Ref : Toxicol Lett , 262 :92 , 2016 |
| Abstract : |
| PubMedSearch : Kodani_2016_Toxicol.Lett_262_92 |
| PubMedID: 27659731 |
| Title : Inhibition of soluble epoxide hydrolase as a novel approach to high dose diazepam induced hypotension - Ulu_2016_J.Clin.Toxicol_6_ |
| Author(s) : Ulu A , Inceoglu B , Yang J , Singh V , Vito S , Wulff H , Hammock BD |
| Ref : J Clinical Toxicology , 6 : , 2016 |
| Abstract : |
| PubMedSearch : Ulu_2016_J.Clin.Toxicol_6_ |
| PubMedID: 28255523 |
| Title : Screening of soluble epoxide hydrolase inhibitory ingredients from traditional Chinese medicines for anti-inflammatory use - Liu_2016_J.Ethnopharmacol_194_475 |
| Author(s) : Liu JY , Morisseau C , Huang H , Hammock BD |
| Ref : J Ethnopharmacol , 194 :475 , 2016 |
| Abstract : |
| PubMedSearch : Liu_2016_J.Ethnopharmacol_194_475 |
| PubMedID: 27702689 |
| Title : Effects of juvenile hormone (JH) analog insecticides on larval development and JH esterase activity in two spodopterans - El-Sheikh_2016_Pestic.Biochem.Physiol_128_30 |
| Author(s) : El-Sheikh el SA , Kamita SG , Hammock BD |
| Ref : Pestic Biochem Physiol , 128 :30 , 2016 |
| Abstract : |
| PubMedSearch : El-Sheikh_2016_Pestic.Biochem.Physiol_128_30 |
| PubMedID: 26969437 |
| Title : Dysregulation of soluble epoxide hydrolase and lipidomic profiles in anorexia nervosa - Shih_2016_Mol.Psychiatry_21_537 |
| Author(s) : Shih PB , Yang J , Morisseau C , German JB , Zeeland AA , Armando AM , Quehenberger O , Bergen AW , Magistretti P , Berrettini W , Halmi KA , Schork N , Hammock BD , Kaye W |
| Ref : Mol Psychiatry , 21 :537 , 2016 |
| Abstract : |
| PubMedSearch : Shih_2016_Mol.Psychiatry_21_537 |
| PubMedID: 25824304 |
| Gene_locus related to this paper: human-EPHX2 |
| Title : Rational Design of Potent and Selective Inhibitors of an Epoxide Hydrolase Virulence Factor from Pseudomonas aeruginosa - Kitamura_2016_J.Med.Chem_59_4790 |
| Author(s) : Kitamura S , Hvorecny KL , Niu J , Hammock BD , Madden DR , Morisseau C |
| Ref : Journal of Medicinal Chemistry , 59 :4790 , 2016 |
| Abstract : |
| PubMedSearch : Kitamura_2016_J.Med.Chem_59_4790 |
| PubMedID: 27120257 |
| Gene_locus related to this paper: pseae-PA2934 |
| Title : Models to identify treatments for the acute and persistent effects of seizure-inducing chemical threat agents - Pessah_2016_Ann.N.Y.Acad.Sci_1378_124 |
| Author(s) : Pessah IN , Rogawski MA , Tancredi DJ , Wulff H , Zolkowska D , Bruun DA , Hammock BD , Lein PJ |
| Ref : Annals of the New York Academy of Sciences , 1378 :124 , 2016 |
| Abstract : |
| PubMedSearch : Pessah_2016_Ann.N.Y.Acad.Sci_1378_124 |
| PubMedID: 27467073 |
| Title : Inhibition of soluble epoxide hydrolase does not improve the course of congestive heart failure and the development of renal dysfunction in rats with volume overload induced by aorto-caval fistula - Cervenka_2015_Physiol.Res_64_857 |
| Author(s) : Cervenka L , Melenovsky V , Huskova Z , Sporkova A , Burgelova M , Skaroupkova P , Hwang SH , Hammock BD , Imig JD , Sadowski J |
| Ref : Physiol Res , 64 :857 , 2015 |
| Abstract : |
| PubMedSearch : Cervenka_2015_Physiol.Res_64_857 |
| PubMedID: 26047375 |
| Title : Omeprazole increases the efficacy of a soluble epoxide hydrolase inhibitor in a PGE2 induced pain model - Goswami_2015_Toxicol.Appl.Pharmacol_289_419 |
| Author(s) : Goswami SK , Inceoglu B , Yang J , Wan D , Kodani SD , da Silva CA , Morisseau C , Hammock BD |
| Ref : Toxicol Appl Pharmacol , 289 :419 , 2015 |
| Abstract : |
| PubMedSearch : Goswami_2015_Toxicol.Appl.Pharmacol_289_419 |
| PubMedID: 26522832 |
| Title : Potent natural soluble epoxide hydrolase inhibitors from Pentadiplandra brazzeana baillon: synthesis, quantification, and measurement of biological activities in vitro and in vivo - Kitamura_2015_PLoS.One_10_e0117438 |
| Author(s) : Kitamura S , Morisseau C , Inceoglu B , Kamita SG , De Nicola GR , Nyegue M , Hammock BD |
| Ref : PLoS ONE , 10 :e0117438 , 2015 |
| Abstract : |
| PubMedSearch : Kitamura_2015_PLoS.One_10_e0117438 |
| PubMedID: 25659109 |
| Title : Peripheral FAAH and soluble epoxide hydrolase inhibitors are synergistically antinociceptive - Sasso_2015_Pharmacol.Res_97_7 |
| Author(s) : Sasso O , Wagner K , Morisseau C , Inceoglu B , Hammock BD , Piomelli D |
| Ref : Pharmacol Res , 97 :7 , 2015 |
| Abstract : |
| PubMedSearch : Sasso_2015_Pharmacol.Res_97_7 |
| PubMedID: 25882247 |
| Title : Inhibiting an Epoxide Hydrolase Virulence Factor from Pseudomonas aeruginosa Protects CFTR - Bahl_2015_Angew.Chem.Int.Ed.Engl_54_9881 |
| Author(s) : Bahl CD , Hvorecny KL , Bomberger JM , Stanton BA , Hammock BD , Morisseau C , Madden DR |
| Ref : Angew Chem Int Ed Engl , 54 :9881 , 2015 |
| Abstract : |
| PubMedSearch : Bahl_2015_Angew.Chem.Int.Ed.Engl_54_9881 |
| PubMedID: 26136396 |
| Gene_locus related to this paper: pseae-PA2934 |
| Title : 1,3-Disubstituted and 1,3,3-trisubstituted adamantyl-ureas with isoxazole as soluble epoxide hydrolase inhibitors - Burmistrov_2015_Bioorg.Med.Chem.Lett_25_5514 |
| Author(s) : Burmistrov V , Morisseau C , Danilov D , Harris TR , Dalinger I , Vatsadze I , Shkineva T , Butov GM , Hammock BD |
| Ref : Bioorganic & Medicinal Chemistry Lett , 25 :5514 , 2015 |
| Abstract : |
| PubMedSearch : Burmistrov_2015_Bioorg.Med.Chem.Lett_25_5514 |
| PubMedID: 26520661 |
| Title : Inhibition of soluble epoxide hydrolase in mice promotes reverse cholesterol transport and regression of atherosclerosis - Shen_2015_Atherosclerosis_239_557 |
| Author(s) : Shen L , Peng H , Peng R , Fan Q , Zhao S , Xu D , Morisseau C , Chiamvimonvat N , Hammock BD |
| Ref : Atherosclerosis , 239 :557 , 2015 |
| Abstract : |
| PubMedSearch : Shen_2015_Atherosclerosis_239_557 |
| PubMedID: 25733327 |
| Title : In vitro and in vivo metabolism of N-adamantyl substituted urea-based soluble epoxide hydrolase inhibitors - Liu_2015_Biochem.Pharmacol_98_718 |
| Author(s) : Liu JY , Tsai HJ , Morisseau C , Lango J , Hwang SH , Watanabe T , Kim IH , Hammock BD |
| Ref : Biochemical Pharmacology , 98 :718 , 2015 |
| Abstract : |
| PubMedSearch : Liu_2015_Biochem.Pharmacol_98_718 |
| PubMedID: 26494425 |
| Title : Soluble Epoxide Hydrolase Pharmacological Inhibition Ameliorates Experimental Acute Pancreatitis in Mice - Bettaieb_2015_Mol.Pharmacol_88_281 |
| Author(s) : Bettaieb A , Chahed S , Bachaalany S , Griffey S , Hammock BD , Haj FG |
| Ref : Molecular Pharmacology , 88 :281 , 2015 |
| Abstract : |
| PubMedSearch : Bettaieb_2015_Mol.Pharmacol_88_281 |
| PubMedID: 25993999 |
| Title : Oral treatment of rodents with soluble epoxide hydrolase inhibitor 1-(1-propanoylpiperidin-4-yl)-3-[4-(trifluoromethoxy)phenyl]urea (TPPU): Resulting drug levels and modulation of oxylipin pattern - Ostermann_2015_Prostaglandins.Other.Lipid.Mediat_121_131 |
| Author(s) : Ostermann AI , Herbers J , Willenberg I , Chen R , Hwang SH , Greite R , Morisseau C , Gueler F , Hammock BD , Schebb NH |
| Ref : Prostaglandins Other Lipid Mediat , 121 :131 , 2015 |
| Abstract : |
| PubMedSearch : Ostermann_2015_Prostaglandins.Other.Lipid.Mediat_121_131 |
| PubMedID: 26117215 |
| Title : Identification of potent inhibitors of the chicken soluble epoxide hydrolase - Shihadih_2015_Bioorg.Med.Chem.Lett_25_276 |
| Author(s) : Shihadih DS , Harris TR , Yang J , Merzlikin O , Lee KS , Hammock BD , Morisseau C |
| Ref : Bioorganic & Medicinal Chemistry Lett , 25 :276 , 2015 |
| Abstract : |
| PubMedSearch : Shihadih_2015_Bioorg.Med.Chem.Lett_25_276 |
| PubMedID: 25479771 |
| Title : Epoxide hydrolase activities and epoxy fatty acids in the mosquito Culex quinquefasciatus - Xu_2015_Insect.Biochem.Mol.Biol_59_41 |
| Author(s) : Xu J , Morisseau C , Yang J , Mamatha DM , Hammock BD |
| Ref : Insect Biochemistry & Molecular Biology , 59 :41 , 2015 |
| Abstract : |
| PubMedSearch : Xu_2015_Insect.Biochem.Mol.Biol_59_41 |
| PubMedID: 25686802 |
| Title : Juvenile hormone (JH) esterase activity but not JH epoxide hydrolase activity is downregulated in larval Adoxophyes honmai following nucleopolyhedroviruses infection - Saito_2015_J.Insect.Physiol_80_71 |
| Author(s) : Saito Y , Kamita SG , Hammock BD , Kunimi Y , Inoue MN , Nakai M |
| Ref : J Insect Physiol , 80 :71 , 2015 |
| Abstract : |
| PubMedSearch : Saito_2015_J.Insect.Physiol_80_71 |
| PubMedID: 25727179 |
| Gene_locus related to this paper: adoho-a0a0g4dcw7 |
| Title : A photorhabdus natural product inhibits insect juvenile hormone epoxide hydrolase - Nollmann_2015_Chembiochem_16_766 |
| Author(s) : Nollmann FI , Heinrich AK , Brachmann AO , Morisseau C , Mukherjee K , Casanova-Torres AM , Strobl F , Kleinhans D , Kinski S , Schultz K , Beeton ML , Kaiser M , Chu YY , Phan Ke L , Thanwisai A , Bozhuyuk KA , Chantratita N , Gotz F , Waterfield NR , Vilcinskas A , Stelzer EH , Goodrich-Blair H , Hammock BD , Bode HB |
| Ref : Chembiochem , 16 :766 , 2015 |
| Abstract : |
| PubMedSearch : Nollmann_2015_Chembiochem_16_766 |
| PubMedID: 25711603 |
| Title : Structure-activity relationships of amide-phosphonate derivatives as inhibitors of the human soluble epoxide hydrolase - Kim_2015_Bioorg.Med.Chem_23_7199 |
| Author(s) : Kim IH , Park YK , Nishiwaki H , Hammock BD , Nishi K |
| Ref : Bioorganic & Medicinal Chemistry , 23 :7199 , 2015 |
| Abstract : |
| PubMedSearch : Kim_2015_Bioorg.Med.Chem_23_7199 |
| PubMedID: 26507430 |
| Title : Heavy chain single-domain antibodies to detect native human soluble epoxide hydrolase - Cui_2015_Anal.Bioanal.Chem_407_7275 |
| Author(s) : Cui Y , Li D , Morisseau C , Dong JX , Yang J , Wan D , Rossotti MA , Gee SJ , Gonzalez-Sapienza GG , Hammock BD |
| Ref : Anal Bioanal Chem , 407 :7275 , 2015 |
| Abstract : |
| PubMedSearch : Cui_2015_Anal.Bioanal.Chem_407_7275 |
| PubMedID: 26229025 |
| Title : The 2014 bernard B. Brodie award lecture-epoxide hydrolases: drug metabolism to therapeutics for chronic pain - Kodani_2015_Drug.Metab.Dispos_43_788 |
| Author(s) : Kodani SD , Hammock BD |
| Ref : Drug Metabolism & Disposition: The Biological Fate of Chemicals , 43 :788 , 2015 |
| Abstract : |
| PubMedSearch : Kodani_2015_Drug.Metab.Dispos_43_788 |
| PubMedID: 25762541 |
| Title : Endoplasmic reticulum stress in the peripheral nervous system is a significant driver of neuropathic pain - Inceoglu_2015_Proc.Natl.Acad.Sci.U.S.A_112_9082 |
| Author(s) : Inceoglu B , Bettaieb A , Trindade da Silva CA , Lee KS , Haj FG , Hammock BD |
| Ref : Proc Natl Acad Sci U S A , 112 :9082 , 2015 |
| Abstract : |
| PubMedSearch : Inceoglu_2015_Proc.Natl.Acad.Sci.U.S.A_112_9082 |
| PubMedID: 26150506 |
| Title : Inhibition of soluble epoxide hydrolase attenuates hepatic fibrosis and endoplasmic reticulum stress induced by carbon tetrachloride in mice - Harris_2015_Toxicol.Appl.Pharmacol_286_102 |
| Author(s) : Harris TR , Bettaieb A , Kodani S , Dong H , Myers R , Chiamvimonvat N , Haj FG , Hammock BD |
| Ref : Toxicol Appl Pharmacol , 286 :102 , 2015 |
| Abstract : |
| PubMedSearch : Harris_2015_Toxicol.Appl.Pharmacol_286_102 |
| PubMedID: 25827057 |
| Title : Inhibition of soluble epoxide hydrolase modulates inflammation and autophagy in obese adipose tissue and liver: role for omega-3 epoxides - Lopez-Vicario_2015_Proc.Natl.Acad.Sci.U.S.A_112_536 |
| Author(s) : Lopez-Vicario C , Alcaraz-Quiles J , Garcia-Alonso V , Rius B , Hwang SH , Titos E , Lopategi A , Hammock BD , Arroyo V , Claria J |
| Ref : Proc Natl Acad Sci U S A , 112 :536 , 2015 |
| Abstract : |
| PubMedSearch : Lopez-Vicario_2015_Proc.Natl.Acad.Sci.U.S.A_112_536 |
| PubMedID: 25550510 |
| Title : Effects of soluble epoxide hydrolase deficiency on acute pancreatitis in mice - Bettaieb_2014_PLoS.One_9_e113019 |
| Author(s) : Bettaieb A , Chahed S , Tabet G , Yang J , Morisseau C , Griffey S , Hammock BD , Haj FG |
| Ref : PLoS ONE , 9 :e113019 , 2014 |
| Abstract : |
| PubMedSearch : Bettaieb_2014_PLoS.One_9_e113019 |
| PubMedID: 25402489 |
| Title : Expression and characterization of an epoxide hydrolase from Anopheles gambiae with high activity on epoxy fatty acids - Xu_2014_Insect.Biochem.Mol.Biol_54C_42 |
| Author(s) : Xu J , Morisseau C , Hammock BD |
| Ref : Insect Biochemistry & Molecular Biology , 54C :42 , 2014 |
| Abstract : |
| PubMedSearch : Xu_2014_Insect.Biochem.Mol.Biol_54C_42 |
| PubMedID: 25173592 |
| Title : The role of long chain fatty acids and their epoxide metabolites in nociceptive signaling - Wagner_2014_Prostaglandins.Other.Lipid.Mediat_113-115_2 |
| Author(s) : Wagner K , Vito S , Inceoglu B , Hammock BD |
| Ref : Prostaglandins Other Lipid Mediat , 113-115 :2 , 2014 |
| Abstract : |
| PubMedSearch : Wagner_2014_Prostaglandins.Other.Lipid.Mediat_113-115_2 |
| PubMedID: 25240260 |
| Title : Effect of soluble epoxide hydrolase polymorphism on substrate and inhibitor selectivity and dimer formation - Morisseau_2014_J.Lipid.Res_55_1131 |
| Author(s) : Morisseau C , Wecksler AT , Deng C , Dong H , Yang J , Lee KS , Kodani SD , Hammock BD |
| Ref : J Lipid Res , 55 :1131 , 2014 |
| Abstract : |
| PubMedSearch : Morisseau_2014_J.Lipid.Res_55_1131 |
| PubMedID: 24771868 |
| Title : Pharmacological inhibition of soluble epoxide hydrolase prevents renal interstitial fibrogenesis in obstructive nephropathy - Kim_2014_Am.J.Physiol.Renal.Physiol__ajprenal 00531 2014 |
| Author(s) : Kim J , Yoon SP , Toews ML , Imig JD , Hwang SH , Hammock BD , Padanilam BJ |
| Ref : American Journal of Physiology Renal Physiol , :ajprenal 00531 2014 , 2014 |
| Abstract : |
| PubMedSearch : Kim_2014_Am.J.Physiol.Renal.Physiol__ajprenal 00531 2014 |
| PubMedID: 25377915 |
| Title : Aberrant soluble epoxide hydrolase and oxylipin levels in a porcine arteriovenous graft stenosis model - Terry_2014_J.Vasc.Res_51_269 |
| Author(s) : Terry CM , Carlson ML , He Y , Ulu A , Morisseau C , Blumenthal DK , Hammock BD , Cheung AK |
| Ref : J Vasc Res , 51 :269 , 2014 |
| Abstract : |
| PubMedSearch : Terry_2014_J.Vasc.Res_51_269 |
| PubMedID: 25196102 |
| Title : Structure-activity relationships of substituted oxyoxalamides as inhibitors of the human soluble epoxide hydrolase - Kim_2014_Bioorg.Med.Chem_22_1163 |
| Author(s) : Kim IH , Lee IH , Nishiwaki H , Hammock BD , Nishi K |
| Ref : Bioorganic & Medicinal Chemistry , 22 :1163 , 2014 |
| Abstract : |
| PubMedSearch : Kim_2014_Bioorg.Med.Chem_22_1163 |
| PubMedID: 24433964 |
| Title : Symmetric adamantyl-diureas as soluble epoxide hydrolase inhibitors - Burmistrov_2014_Bioorg.Med.Chem.Lett_24_2193 |
| Author(s) : Burmistrov V , Morisseau C , Lee KS , Shihadih DS , Harris TR , Butov GM , Hammock BD |
| Ref : Bioorganic & Medicinal Chemistry Lett , 24 :2193 , 2014 |
| Abstract : |
| PubMedSearch : Burmistrov_2014_Bioorg.Med.Chem.Lett_24_2193 |
| PubMedID: 24685540 |
| Title : Novel sorafenib-based structural analogues: in-vitro anticancer evaluation of t-MTUCB and t-AUCMB - Wecksler_2014_Anticancer.Drugs_25_433 |
| Author(s) : Wecksler AT , Hwang SH , Wettersten HI , Gilda JE , Patton A , Leon LJ , Carraway KL, 3rd , Gomes AV , Baar K , Weiss RH , Hammock BD |
| Ref : Anticancer Drugs , 25 :433 , 2014 |
| Abstract : |
| PubMedSearch : Wecksler_2014_Anticancer.Drugs_25_433 |
| PubMedID: 24525589 |
| Title : Dual inhibition of cyclooxygenase-2 and soluble epoxide hydrolase synergistically suppresses primary tumor growth and metastasis - Zhang_2014_Proc.Natl.Acad.Sci.U.S.A_111_11127 |
| Author(s) : Zhang G , Panigrahy D , Hwang SH , Yang J , Mahakian LM , Wettersten HI , Liu JY , Wang Y , Ingham ES , Tam S , Kieran MW , Weiss RH , Ferrara KW , Hammock BD |
| Ref : Proc Natl Acad Sci U S A , 111 :11127 , 2014 |
| Abstract : |
| PubMedSearch : Zhang_2014_Proc.Natl.Acad.Sci.U.S.A_111_11127 |
| PubMedID: 25024195 |
| Title : Optimized inhibitors of soluble epoxide hydrolase improve in vitro target residence time and in vivo efficacy - Lee_2014_J.Med.Chem_57_7016 |
| Author(s) : Lee KS , Liu JY , Wagner KM , Pakhomova S , Dong H , Morisseau C , Fu SH , Yang J , Wang P , Ulu A , Mate CA , Nguyen LV , Hwang SH , Edin ML , Mara AA , Wulff H , Newcomer ME , Zeldin DC , Hammock BD |
| Ref : Journal of Medicinal Chemistry , 57 :7016 , 2014 |
| Abstract : |
| PubMedSearch : Lee_2014_J.Med.Chem_57_7016 |
| PubMedID: 25079952 |
| Gene_locus related to this paper: human-EPHX2 |
| Title : Post-exposure administration of diazepam combined with soluble epoxide hydrolase inhibition stops seizures and modulates neuroinflammation in a murine model of acute TETS intoxication - Vito_2014_Toxicol.Appl.Pharmacol_281_185 |
| Author(s) : Vito ST , Austin AT , Banks CN , Inceoglu B , Bruun DA , Zolkowska D , Tancredi DJ , Rogawski MA , Hammock BD , Lein PJ |
| Ref : Toxicol Appl Pharmacol , 281 :185 , 2014 |
| Abstract : |
| PubMedSearch : Vito_2014_Toxicol.Appl.Pharmacol_281_185 |
| PubMedID: 25448683 |
| Title : Opposite effects of gene deficiency and pharmacological inhibition of soluble epoxide hydrolase on cardiac fibrosis - Li_2014_PLoS.One_9_e94092 |
| Author(s) : Li L , Li N , Pang W , Zhang X , Hammock BD , Ai D , Zhu Y |
| Ref : PLoS ONE , 9 :e94092 , 2014 |
| Abstract : |
| PubMedSearch : Li_2014_PLoS.One_9_e94092 |
| PubMedID: 24718617 |
| Title : Synthesis and functional survey of new Tacrine analogs modified with nitroxides or their precursors - Kalai_2014_Eur.J.Med.Chem_77C_343 |
| Author(s) : Kalai T , Altman R , Maezawa I , Balog M , Morisseau C , Petrlova J , Hammock BD , Jin LW , Trudell JR , Voss JC , Hideg K |
| Ref : Eur Journal of Medicinal Chemistry , 77C :343 , 2014 |
| Abstract : |
| PubMedSearch : Kalai_2014_Eur.J.Med.Chem_77C_343 |
| PubMedID: 24657571 |
| Title : Protection from hypertension in mice by the Mediterranean diet is mediated by nitro fatty acid inhibition of soluble epoxide hydrolase - Charles_2014_Proc.Natl.Acad.Sci.U.S.A_111_8167 |
| Author(s) : Charles RL , Rudyk O , Prysyazhna O , Kamynina A , Yang J , Morisseau C , Hammock BD , Freeman BA , Eaton P |
| Ref : Proc Natl Acad Sci U S A , 111 :8167 , 2014 |
| Abstract : |
| PubMedSearch : Charles_2014_Proc.Natl.Acad.Sci.U.S.A_111_8167 |
| PubMedID: 24843165 |
| Title : Frster resonance energy transfer competitive displacement assay for human soluble epoxide hydrolase - Lee_2013_Anal.Biochem_434_259 |
| Author(s) : Lee KS , Morisseau C , Yang J , Wang P , Hwang SH , Hammock BD |
| Ref : Analytical Biochemistry , 434 :259 , 2013 |
| Abstract : |
| PubMedSearch : Lee_2013_Anal.Biochem_434_259 |
| PubMedID: 23219719 |
| Title : Antihypertensive action of soluble epoxide hydrolase inhibition in Ren-2 transgenic rats is mediated by suppression of the intrarenal renin-angiotensin system - Varcabova_2013_Clin.Exp.Pharmacol.Physiol_40_273 |
| Author(s) : Varcabova S , Huskova Z , Kramer HJ , Hwang SH , Hammock BD , Imig JD , Kitada K , Cervenka L |
| Ref : Clinical & Experimental Pharmacology & Physiology , 40 :273 , 2013 |
| Abstract : |
| PubMedSearch : Varcabova_2013_Clin.Exp.Pharmacol.Physiol_40_273 |
| PubMedID: 23039246 |
| Title : Soluble epoxide hydrolase: Gene structure, expression and deletion - Harris_2013_Gene_526_61 |
| Author(s) : Harris TR , Hammock BD |
| Ref : Gene , 526 :61 , 2013 |
| Abstract : |
| PubMedSearch : Harris_2013_Gene_526_61 |
| PubMedID: 23701967 |
| Title : Soluble epoxide hydrolase inhibitor trans-4-[4-(3-adamantan-1-yl-ureido)-cyclohexyloxy]-benzoic acid is neuroprotective in rat model of ischemic stroke - Shaik_2013_Am.J.Physiol.Heart.Circ.Physiol_305_H1605 |
| Author(s) : Shaik JS , Ahmad M , Li W , Rose ME , Foley LM , Hitchens TK , Graham SH , Hwang SH , Hammock BD , Poloyac SM |
| Ref : American Journal of Physiology Heart Circ Physiol , 305 :H1605 , 2013 |
| Abstract : |
| PubMedSearch : Shaik_2013_Am.J.Physiol.Heart.Circ.Physiol_305_H1605 |
| PubMedID: 24043255 |
| Title : Characterization of HOVI-MEH1, a microsomal epoxide hydrolase from the glassy-winged sharpshooter Homalodisca vitripennis - Kamita_2013_Arch.Insect.Biochem.Physiol_83_171 |
| Author(s) : Kamita SG , Oshita GH , Wang P , Morisseau C , Hammock BD , Nandety RS , Falk BW |
| Ref : Archives of Insect Biochemistry & Physiology , 83 :171 , 2013 |
| Abstract : |
| PubMedSearch : Kamita_2013_Arch.Insect.Biochem.Physiol_83_171 |
| PubMedID: 23704009 |
| Title : Therapeutic activity of inhibition of the soluble epoxide hydrolase in a mouse model of scrapie - Poli_2013_Life.Sci_92_1145 |
| Author(s) : Poli G , Corda E , Martino PA , Dall'ara P , Bareggi SR , Bondiolotti G , Iulini B , Mazza M , Casalone C , Hwang SH , Hammock BD , Inceoglu B |
| Ref : Life Sciences , 92 :1145 , 2013 |
| Abstract : |
| PubMedSearch : Poli_2013_Life.Sci_92_1145 |
| PubMedID: 23651659 |
| Title : Development of On-line Liquid Chromatography-Biochemical Detection for Soluble Epoxide Hydrolase Inhibitors in Mixtures - Falck_2013_Chromatographia_76_13 |
| Author(s) : Falck D , Schebb NH , Prihatiningtyas S , Zhang J , Heus F , Morisseau C , Kool J , Hammock BD , Niessen WM |
| Ref : Chromatographia , 76 :13 , 2013 |
| Abstract : |
| PubMedSearch : Falck_2013_Chromatographia_76_13 |
| PubMedID: 23526703 |
| Title : Substituted phenyl groups improve the pharmacokinetic profile and anti-inflammatory effect of urea-based soluble epoxide hydrolase inhibitors in murine models - Liu_2013_Eur.J.Pharm.Sci_48_619 |
| Author(s) : Liu JY , Lin YP , Qiu H , Morisseau C , Rose TE , Hwang SH , Chiamvimonvat N , Hammock BD |
| Ref : Eur J Pharm Sci , 48 :619 , 2013 |
| Abstract : |
| PubMedSearch : Liu_2013_Eur.J.Pharm.Sci_48_619 |
| PubMedID: 23291046 |
| Title : Impact of soluble epoxide hydrolase and epoxyeicosanoids on human health - Morisseau_2013_Annu.Rev.Pharmacol.Toxicol_53_37 |
| Author(s) : Morisseau C , Hammock BD |
| Ref : Annual Review of Pharmacology & Toxicology , 53 :37 , 2013 |
| Abstract : |
| PubMedSearch : Morisseau_2013_Annu.Rev.Pharmacol.Toxicol_53_37 |
| PubMedID: 23020295 |
| Title : Soluble Epoxide Hydrolase Deficiency Inhibits Dextran Sulfate Sodium-induced Colitis and Carcinogenesis in Mice - Zhang_2013_Anticancer.Res_33_5261 |
| Author(s) : Zhang W , Li H , Dong H , Liao J , Hammock BD , Yang GY |
| Ref : Anticancer Research , 33 :5261 , 2013 |
| Abstract : |
| PubMedSearch : Zhang_2013_Anticancer.Res_33_5261 |
| PubMedID: 24324059 |
| Title : Beneficial effects of inhibition of soluble epoxide hydrolase on glucose homeostasis and islet damage in a streptozotocin-induced diabetic mouse model - Chen_2013_Prostaglandins.Other.Lipid.Mediat_104-105_42 |
| Author(s) : Chen L , Fan C , Zhang Y , Bakri M , Dong H , Morisseau C , Maddipati KR , Luo P , Wang CY , Hammock BD , Wang MH |
| Ref : Prostaglandins Other Lipid Mediat , 104-105 :42 , 2013 |
| Abstract : |
| PubMedSearch : Chen_2013_Prostaglandins.Other.Lipid.Mediat_104-105_42 |
| PubMedID: 23247129 |
| Title : Cloning and characterization of a microsomal epoxide hydrolase from Heliothis virescens - Kamita_2013_Insect.Biochem.Mol.Biol_43_219 |
| Author(s) : Kamita SG , Yamamoto K , Dadala MM , Pha K , Morisseau C , Escaich A , Hammock BD |
| Ref : Insect Biochemistry & Molecular Biology , 43 :219 , 2013 |
| Abstract : |
| PubMedSearch : Kamita_2013_Insect.Biochem.Mol.Biol_43_219 |
| PubMedID: 23276675 |
| Gene_locus related to this paper: helvi-l7r9x8 |
| Title : Soluble Epoxide Hydrolase Deficiency or Inhibition Attenuates Diet-induced Endoplasmic Reticulum Stress in Liver and Adipose Tissue - Bettaieb_2013_J.Biol.Chem_288_14189 |
| Author(s) : Bettaieb A , Nagata N , Aboubechara D , Chahed S , Morisseau C , Hammock BD , Haj FG |
| Ref : Journal of Biological Chemistry , 288 :14189 , 2013 |
| Abstract : |
| PubMedSearch : Bettaieb_2013_J.Biol.Chem_288_14189 |
| PubMedID: 23576437 |
| Title : Soluble epoxide hydrolase inhibitor, TUPS, protects against isoprenaline-induced cardiac hypertrophy - Althurwi_2013_Br.J.Pharmacol_168_1794 |